Cryo-EM Analysis of AE1 Structure in 100 mM NaHCO3 Buffer: Form1
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Carbonate ion (60 Da, Ligand)
- Ae1 (Complex from Homo sapiens)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Band 3 anion transport protein (101 kDa, Protein from Homo sapiens)
Cryo-EM Analysis of AE1 Structure in 100 mM NaHCO3 Buffer: Form3
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Carbonate ion (60 Da, Ligand)
- Ae1 (Complex from Homo sapiens)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Band 3 anion transport protein (101 kDa, Protein from Homo sapiens)
Cryo-EM Structure of the Sodium-driven Chloride/Bicarbonate Exchanger NDCBE (SLC4A8)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7rtm
Q-score: 0.251
Wang W, Tsirulnikov K, Zhekova HR, Kayik G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Zhou ZH, Pushkin A, Kurtz I
Nat Commun (2021) 12 pp. 5690-5690 [ Pubmed: 34584093 DOI: doi:10.1038/s41467-021-25998-2 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Carbonate ion (60 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Electroneutral sodium bicarbonate exchanger 1 (64 kDa, Protein from Oryctolagus cuniculus)
- Ndcbe(slc4a8) dimer (Complex from Oryctolagus cuniculus)
Plasmodium vivax M17 leucyl aminopeptidase Pv-M17
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 7k5k
Q-score: 0.618
Malcolm TR, Belousoff MJ, Venugopal H, Borg NA, Drinkwater N, Atkinson SC, McGowan S
J Biol Chem (2020) 296 pp. 100173-100173 [ Pubmed: 33303633 DOI: doi:10.1074/jbc.RA120.016313 ]
- Pvm17-hexamer (Complex from Plasmodium vivax)
- M17 leucyl aminopeptidase, putative (60 kDa, Protein from Plasmodium vivax)
- Carbonate ion (60 Da, Ligand)
- Manganese (ii) ion (54 Da, Ligand)
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 6d03
Q-score: 0.482
Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH
Nature (2018) 559 pp. 135-139 [ DOI: doi:10.1038/s41586-018-0249-1 Pubmed: 29950717 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Carbonate ion (60 Da, Ligand)
- Ternary complex between human transferrin receptor 1, transferrin and plasmodium vivax reticulocyte-binding protein 2b (Complex from homo sapiens)
- Reticulocyte binding protein 2, putative (96 kDa, Protein from Plasmodium vivax)
- Transferrin receptor protein 1 (73 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Fe (iii) ion (55 Da, Ligand)
- Serotransferrin (77 kDa, Protein from Human)
Resolution: 3.74 Å
EM Method: Single-particle
Fitted PDBs: 6d04
Q-score: 0.444
Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH
Nature (2018) 559 pp. 135-139 [ DOI: doi:10.1038/s41586-018-0249-1 Pubmed: 29950717 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Carbonate ion (60 Da, Ligand)
- Reticulocyte binding protein 2, putative (96 kDa, Protein from Plasmodium vivax)
- Transferrin receptor protein 1 (73 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Ternary complex between human transferrin receptor 1, transferrin and plasmodium vivax reticulocyte-binding protein 2b (Complex from Homo sapiens)
- Fe (iii) ion (55 Da, Ligand)
- Serotransferrin (77 kDa, Protein from Human)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6d05
Q-score: 0.419
Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH
Nature (2018) 559 pp. 135-139 [ Pubmed: 29950717 DOI: doi:10.1038/s41586-018-0249-1 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Carbonate ion (60 Da, Ligand)
- Ternary complex between human transferrin receptor 1, transferrin and plasmodium vivax reticulocyte-binding protein 2b (Complex from homo sapiens)
- Fe (iii) ion (55 Da, Ligand)
- Serotransferrin (77 kDa, Protein from Human)
- Reticulocyte binding protein 2, putative (96 kDa, Protein from Plasmodium vivax)
- Calcium ion (40 Da, Ligand)
- Transferrin receptor protein 1 (73 kDa, Protein from Homo sapiens)