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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"CDC40 isoform 1"

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EMD-30637

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Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5 angstrom

Release date: March 17, 2021
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7dco
Q-score: 0.408

Bai R, Wan R, Yan C, Jia Q, Lei J, Shi Y

Science (2021) 371 [ DOI: doi:10.1126/science.abe8863 Pubmed: 33243853 ]

Sample:

U2 snrna (376 kDa, RNA from Saccharomyces cerevisiae)
Pre-mrna-processing factor 19 (56 kDa, Protein from Saccharomyces cerevisiae)
Brr2 isoform 1 (246 kDa, Protein from Saccharomyces cerevisiae)
Pre-mrna-splicing factor slt11 (40 kDa, Protein from Saccharomyces cerevisiae)
Cwc27 isoform 1 (35 kDa, Protein from Saccharomyces cerevisiae)
Bj4_g0056610.mrna.1.cds.1 (12 kDa, Protein from Saccharomyces cerevisiae)
Pre-mrna-splicing factor cwc21 (15 kDa, Protein from Saccharomyces cerevisiae)
Hlj1_g0053790.mrna.1.cds.1 (27 kDa, Protein from Saccharomyces cerevisiae)
Bj4_g0027490.mrna.1.cds.1 (12 kDa, Protein from Saccharomyces cerevisiae)
Rse1 isoform 1 (153 kDa, Protein from Saccharomyces cerevisiae)
Guanosine-5'-triphosphate (523 Da, Ligand)
Hsh49 isoform 1 (24 kDa, Protein from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein sm d3 (8 kDa, Protein from Saccharomyces cerevisiae)
Prp9 isoform 1 (63 kDa, Protein from Saccharomyces cerevisiae)
Inositol hexakisphosphate (660 Da, Ligand)
Prp11 isoform 1 (29 kDa, Protein from Saccharomyces cerevisiae)
Hlj1_g0054350.mrna.1.cds.1 (37 kDa, Protein from Saccharomyces cerevisiae)
Sx2_g0027210.mrna.1.cds.1 (14 kDa, Protein from Saccharomyces cerevisiae)
Cdc40 isoform 1 (52 kDa, Protein from Saccharomyces cerevisiae)
Pre-mrna-splicing factor cwc24 (29 kDa, Protein from Saccharomyces cerevisiae)
Snt309 isoform 1 (20 kDa, Protein from Saccharomyces cerevisiae)
Pre-mrna-splicing factor atp-dependent rna helicase-like protein prp2 (99 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Prp8 isoform 1 (279 kDa, Protein from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Bud31 isoform 1 (18 kDa, Protein from Saccharomyces cerevisiae)
Bj4_g0037700.mrna.1.cds.1 (12 kDa, Protein from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Saccharomyces cerevisiae)
Calcium ion (40 Da, Ligand)
Pre-mrna-splicing factor cwc2 (29 kDa, Protein from Saccharomyces cerevisiae)
Pre-mrna-splicing factor cwc26 (14 kDa, Protein from Saccharomyces cerevisiae)
Cwc22 isoform 1 (67 kDa, Protein from Saccharomyces cerevisiae)
Zinc ion (65 Da, Ligand)
Hlj1_g0043010.mrna.1.cds.1 (27 kDa, Protein from Saccharomyces cerevisiae)
Hsh155 isoform 1 (110 kDa, Protein from Saccharomyces cerevisiae)
Syf1 isoform 1 (100 kDa, Protein from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Saccharomyces cerevisiae)
Pre-mrna-splicing factor cwc15 (19 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Clf1 isoform 1 (82 kDa, Protein from Saccharomyces cerevisiae)
Bj4_g0014900.mrna.1.cds.1 (22 kDa, Protein from Saccharomyces cerevisiae)
Smd1 isoform 1 (16 kDa, Protein from Saccharomyces cerevisiae)
Water (18 Da, Ligand)
Magnesium ion (24 Da, Ligand)
U5 snrna (68 kDa, RNA from Saccharomyces cerevisiae)
Snu114 isoform 1 (114 kDa, Protein from Saccharomyces cerevisiae)
Pre-mrna-processing protein 45 (42 kDa, Protein from Saccharomyces cerevisiae)
Pre-mrna-splicing factor spp2 (20 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
The activated spliceosome bact complex (Complex from Saccharomyces cerevisiae)
Pre-mrna-splicing factor cef1 (67 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Rds3 complex subunit 10 (9 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Pre-mrna leakage protein 1 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Pre-mrna (44 kDa, RNA from Saccharomyces cerevisiae)
Pre-mrna-splicing factor prp21 (33 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Sm protein f (9 kDa, Protein from Saccharomyces cerevisiae)
U6 snrna (35 kDa, RNA from Saccharomyces cerevisiae)

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EMD-12106

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Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound, composite map

Release date: March 10, 2021
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7b9v
Q-score: 0.378

Wilkinson ME, Fica SM, Galej WP, Nagai K

Mol Cell (2021) 81 pp. 1439- [ Pubmed: 33705709 DOI: doi:10.1016/j.molcel.2021.02.021 ]

Sample:

Clf1 isoform 1 (82 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor cwc21 (15 kDa, Protein from Baker's yeast)
Pre-mrna-splicing helicase brr2 (246 kDa, Protein from Baker's yeast)
5' exon of ubc4 mrna (15 kDa, RNA from Saccharomyces cerevisiae)
Pre-mrna-splicing factor snu114 (114 kDa, Protein from Baker's yeast)
Syf1 isoform 1 (100 kDa, Protein from Baker's yeast)
Guanosine-5'-triphosphate (523 Da, Ligand)
Pre-mrna-splicing factor cwc25 (20 kDa, Protein from Baker's yeast)
Bj4_g0054360.mrna.1.cds.1 (50 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor slt11 (40 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor syf2 (24 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor cwc15 (19 kDa, Protein from Baker's yeast)
Hlj1_g0053790.mrna.1.cds.1 (27 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Baker's yeast)
D-chiro inositol hexakisphosphate (660 Da, Ligand)
Snt309 isoform 1 (20 kDa, Protein from Baker's yeast)
Pre-mrna-processing factor 19 (56 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor isy1 (27 kDa, Protein from Baker's yeast)
Potassium ion (39 Da, Ligand)
Branched intron and 3' exon of ubc4 pre-mrna (30 kDa, RNA from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Baker's yeast)
Zinc ion (65 Da, Ligand)
Pre-mrna-splicing factor cwc2 (38 kDa, Protein from Baker's yeast)
Cwc22 isoform 1 (67 kDa, Protein from Baker's yeast)
Bj4_g0027490.mrna.1.cds.1 (12 kDa, Protein from Baker's yeast)
Ntc20 isoform 1 (15 kDa, Protein from Baker's yeast)
Pre-mrna-processing protein 45 (42 kDa, Protein from Baker's yeast)
Splicing factor yju2 (33 kDa, Protein from Baker's yeast)
Cdc40 isoform 1 (52 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein f (9 kDa, Protein from Baker's yeast)
Y55_g0042700.mrna.1.cds.1 (67 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor slu7 (44 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor 18 (28 kDa, Protein from Baker's yeast)
Magnesium ion (24 Da, Ligand)
Pre-mrna-splicing factor atp-dependent rna helicase prp16 (121 kDa, Protein from Baker's yeast)
U5 snrna (68 kDa, RNA from Saccharomyces cerevisiae)
Unassigned structure (20 kDa, Protein from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor 8 (279 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Baker's yeast)
Bud31 isoform 1 (18 kDa, Protein from Baker's yeast)
U2 snrna (376 kDa, RNA from Saccharomyces cerevisiae)
Yeast c complex spliceosome with prp18/slu7 bound (2 MDa, Complex from Saccharomyces cerevisiae)
U6 snrna (35 kDa, RNA from Saccharomyces cerevisiae)

[Show more]

Sort by: Download

Showing 1 - 2 of 2. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [2]

Format:

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Shell (Unix-based) Batch (Windows-based)

Preview first 10

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