Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"Cystinosin-Fab 3H5 complex in cytosol-open conformation" AND xref_links:"pfam"

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EMD-27488

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Cryo-EM structure of cystinosin in a cytosol-open state

Release date: Sept. 21, 2022
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8dke
Q-score: 0.532

Guo X, Schmiege P, Assafa TE, Wang R, Xu Y, Donnelly L, Fine M, Ni X, Jiang J, Millhauser G, Feng L, Li X

Cell (2022) 185 pp. 3739-3752.e18 [ DOI: doi:10.1016/j.cell.2022.08.020 Pubmed: 36113465 ]

Sample:

Isoform 2 of cystinosin (46 kDa, Protein from Homo sapiens)
Cystinosin (Complex from Homo sapiens)
Fab 3h5 heavy chain (26 kDa, Protein from Mus musculus)
Fab 3h5 (Complex from Mus musculus)
Fab 3h5 kappa chain (25 kDa, Protein from Mus musculus)
Cystinosin-fab 3h5 complex in cytosol-open conformation (Complex)

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