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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"GUANOSINE-5'-TRIPHOSPHATE" AND author_orcid:"0000-0003-0930-4249" AND xref_links:"interpro"

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EMD-23936

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Cryo-EM structure of the human SSU processome, state pre-A1

Release date: Sept. 22, 2021
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7mq8
Q-score: 0.417

Singh S, Vanden Broeck A, Miller L, Chaker-Margot M, Klinge S

Science (2021) 373 pp. eabj5338-eabj5338 [ Pubmed: 34516797 DOI: doi:10.1126/science.abj5338 ]

Sample:

U3 small nucleolar rna-associated protein 18 homolog (62 kDa, Protein from Homo sapiens)
Small subunit processome component 20 homolog (318 kDa, Protein from Homo sapiens)
40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
Krr1 small subunit processome component homolog (43 kDa, Protein from Homo sapiens)
40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
Transducin beta-like protein 3 (89 kDa, Protein from Homo sapiens)
40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
5'ets rrna (4 kDa, RNA from Homo sapiens)
Guanosine-5'-triphosphate (523 Da, Ligand)
40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
Rna 3'-terminal phosphate cyclase-like protein (40 kDa, Protein from Homo sapiens)
40s ribosomal protein s18 (12 kDa, Protein from Homo sapiens)
40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
Nucleolar protein 58 (59 kDa, Protein from Homo sapiens)
Nucleolar protein 14 (68 kDa, Protein from Homo sapiens)
Wd repeat-containing protein 36 (105 kDa, Protein from Homo sapiens)
Probable u3 small nucleolar rna-associated protein 11 (30 kDa, Protein from Homo sapiens)
Something about silencing protein 10 (54 kDa, Protein from Homo sapiens)
U3 small nucleolar rna-interacting protein 2 (51 kDa, Protein from Homo sapiens)
Nucleolar protein 56 (66 kDa, Protein from Homo sapiens)
U3 small nucleolar ribonucleoprotein protein imp4 (33 kDa, Protein from Homo sapiens)
Nucleolar protein 11 (73 kDa, Protein from Homo sapiens)
Ribosomal rna-processing protein 7 homolog a (32 kDa, Protein from Homo sapiens)
Nucleolar protein 10 (80 kDa, Protein from Homo sapiens)
Nucleolar protein 6 (127 kDa, Protein from Homo sapiens)
Human ssu processome (5 MDa, Complex from Homo sapiens)
Protein aatf (63 kDa, Protein from Homo sapiens)
Nucleolar complex protein 4 homolog (50 kDa, Protein from Homo sapiens)
Rna cytidine acetyltransferase (115 kDa, Protein from Homo sapiens)
U3 small nucleolar rna-associated protein 14 homolog a (88 kDa, Protein from Homo sapiens)
Heat repeat-containing protein 1 (242 kDa, Protein from Homo sapiens)
5'ets rrna (1 MDa, RNA from Homo sapiens)
40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
Rna-binding protein pno1 (27 kDa, Protein from Homo sapiens)
Wd repeat-containing protein 75 (94 kDa, Protein from Homo sapiens)
Wd repeat-containing protein 46 (68 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
Rrna 2'-o-methyltransferase fibrillarin (33 kDa, Protein from Homo sapiens)
40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
Rrp12-like protein (73 kDa, Protein from Homo sapiens)
Ribosome biogenesis protein bms1 homolog (145 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
Unassigned peptides (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
Periodic tryptophan protein 2 homolog (102 kDa, Protein from Homo sapiens)
Wd repeat-containing protein 43 (74 kDa, Protein from Homo sapiens)
Wd repeat-containing protein 3 (106 kDa, Protein from Homo sapiens)
Nucleolar protein 7 (29 kDa, Protein from Homo sapiens)
40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
S-adenosyl-l-homocysteine (384 Da, Ligand)
Ddb1- and cul4-associated factor 13 (51 kDa, Protein from Homo sapiens)
U3 small nucleolar rna-associated protein 15 homolog (58 kDa, Protein from Homo sapiens)
40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
Rrna-processing protein fcf1 homolog (23 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Neuroguidin (35 kDa, Protein from Homo sapiens)
U3 small nucleolar ribonucleoprotein protein imp3 (21 kDa, Protein from Homo sapiens)
Ribosomal rna small subunit methyltransferase nep1 (26 kDa, Protein from Homo sapiens)
Bystin (33 kDa, Protein from Homo sapiens)
18s rrna (602 kDa, RNA from Homo sapiens)
U3 small nucleolar rna-associated protein 4 homolog (76 kDa, Protein from Homo sapiens)
U3 small nucleolar ribonucleoprotein protein mpp10 (78 kDa, Protein from Homo sapiens)
Uncharacterized protein c1orf131 (32 kDa, Protein from Homo sapiens)
Nhp2-like protein 1 (14 kDa, Protein from Homo sapiens)
40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
U3 small nucleolar rna-associated protein 6 homolog (70 kDa, Protein from Homo sapiens)
40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
Deoxynucleotidyltransferase terminal-interacting protein 2 (84 kDa, Protein from Homo sapiens)
U3 snorna (70 kDa, RNA from Homo sapiens)
40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)

[Show more]

EMD-23937

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Cryo-EM structure of the human SSU processome, state pre-A1*

Release date: Sept. 22, 2021
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 7mq9
Q-score: 0.357

Singh S, Vanden Broeck A, Miller L, Chaker-Margot M, Klinge S

Science (2021) 373 pp. eabj5338-eabj5338 [ Pubmed: 34516797 DOI: doi:10.1126/science.abj5338 ]

Sample:

U3 small nucleolar rna-associated protein 18 homolog (62 kDa, Protein from Homo sapiens)
Small subunit processome component 20 homolog (318 kDa, Protein from Homo sapiens)
40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
Krr1 small subunit processome component homolog (43 kDa, Protein from Homo sapiens)
18s rrna (603 kDa, RNA from Homo sapiens)
40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
40s ribosomal protein s4 x isoform (29 kDa, Protein from Homo sapiens)
Transducin beta-like protein 3 (89 kDa, Protein from Homo sapiens)
40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
Guanosine-5'-triphosphate (523 Da, Ligand)
40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
Rna 3'-terminal phosphate cyclase-like protein (40 kDa, Protein from Homo sapiens)
40s ribosomal protein s18 (12 kDa, Protein from Homo sapiens)
40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
Nucleolar protein 58 (59 kDa, Protein from Homo sapiens)
Nucleolar protein 14 (68 kDa, Protein from Homo sapiens)
Wd repeat-containing protein 36 (105 kDa, Protein from Homo sapiens)
Probable u3 small nucleolar rna-associated protein 11 (30 kDa, Protein from Homo sapiens)
Something about silencing protein 10 (54 kDa, Protein from Homo sapiens)
U3 small nucleolar rna-interacting protein 2 (51 kDa, Protein from Homo sapiens)
Nucleolar protein 56 (66 kDa, Protein from Homo sapiens)
U3 small nucleolar ribonucleoprotein protein imp4 (33 kDa, Protein from Homo sapiens)
Ribosome biogenesis protein bms1 homolog (146 kDa, Protein from Homo sapiens)
Nucleolar protein 10 (80 kDa, Protein from Homo sapiens)
Ribosomal rna-processing protein 7 homolog a (32 kDa, Protein from Homo sapiens)
Nucleolar protein 6 (127 kDa, Protein from Homo sapiens)
Human ssu processome (5 MDa, Complex from Homo sapiens)
Protein aatf (63 kDa, Protein from Homo sapiens)
Nucleolar complex protein 4 homolog (50 kDa, Protein from Homo sapiens)
Rna cytidine acetyltransferase (115 kDa, Protein from Homo sapiens)
U3 small nucleolar rna-associated protein 14 homolog a (88 kDa, Protein from Homo sapiens)
Heat repeat-containing protein 1 (242 kDa, Protein from Homo sapiens)
5'ets rrna (1 MDa, RNA from Homo sapiens)
40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
Rna-binding protein pno1 (27 kDa, Protein from Homo sapiens)
Wd repeat-containing protein 75 (94 kDa, Protein from Homo sapiens)
Wd repeat-containing protein 46 (68 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
Rrna 2'-o-methyltransferase fibrillarin (33 kDa, Protein from Homo sapiens)
40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
Rrp12-like protein (73 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
Unassigned peptides (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
Periodic tryptophan protein 2 homolog (102 kDa, Protein from Homo sapiens)
Wd repeat-containing protein 43 (74 kDa, Protein from Homo sapiens)
Wd repeat-containing protein 3 (106 kDa, Protein from Homo sapiens)
Nucleolar protein 7 (29 kDa, Protein from Homo sapiens)
40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
S-adenosyl-l-homocysteine (384 Da, Ligand)
Ddb1- and cul4-associated factor 13 (51 kDa, Protein from Homo sapiens)
U3 small nucleolar rna-associated protein 15 homolog (58 kDa, Protein from Homo sapiens)
40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
Rrna-processing protein fcf1 homolog (23 kDa, Protein from Homo sapiens)
5' ets rrna (7 kDa, RNA from Homo sapiens)
Magnesium ion (24 Da, Ligand)
U3 small nucleolar ribonucleoprotein protein imp3 (21 kDa, Protein from Homo sapiens)
Nucleolar protein 11 (75 kDa, Protein from Homo sapiens)
Ribosomal rna small subunit methyltransferase nep1 (26 kDa, Protein from Homo sapiens)
Bystin (33 kDa, Protein from Homo sapiens)
U3 small nucleolar rna-associated protein 4 homolog (76 kDa, Protein from Homo sapiens)
U3 small nucleolar ribonucleoprotein protein mpp10 (78 kDa, Protein from Homo sapiens)
Uncharacterized protein c1orf131 (32 kDa, Protein from Homo sapiens)
Nhp2-like protein 1 (14 kDa, Protein from Homo sapiens)
40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
U3 small nucleolar rna-associated protein 6 homolog (70 kDa, Protein from Homo sapiens)
40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
Deoxynucleotidyltransferase terminal-interacting protein 2 (84 kDa, Protein from Homo sapiens)
U3 snorna (70 kDa, RNA from Homo sapiens)
40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)

[Show more]

EMD-23938

Download Map 3D View Raw data

Cryo-EM structure of the human SSU processome, state post-A1

Release date: Sept. 22, 2021
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7mqa
Q-score: 0.526

Singh S, Vanden Broeck A, Miller L, Chaker-Margot M, Klinge S

Science (2021) 373 pp. eabj5338-eabj5338 [ Pubmed: 34516797 DOI: doi:10.1126/science.abj5338 ]

Sample:

40s ribosomal protein s8 (24 kDa, Protein from Human)
Deoxynucleotidyltransferase terminal-interacting protein 2 (84 kDa, Protein from Human)
Rrna 2'-o-methyltransferase fibrillarin (33 kDa, Protein from Human)
Human ssu processome (5 MDa, Complex from Homo sapiens)
U3 small nucleolar rna-associated protein 18 homolog (62 kDa, Protein from Human)
U3 small nucleolar rna-associated protein 14 homolog a (88 kDa, Protein from Human)
40s ribosomal protein s24 (15 kDa, Protein from Human)
Wd repeat-containing protein 36 (105 kDa, Protein from Human)
Nucleolar protein 14 (68 kDa, Protein from Human)
5'ets rrna (1 MDa, RNA from Human)
Nucleolar protein 7 (29 kDa, Protein from Human)
Nucleolar protein 11 (73 kDa, Protein from Human)
Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Human)
40s ribosomal protein s14 (16 kDa, Protein from Human)
Ribosome biogenesis protein bms1 homolog (146 kDa, Protein from Human)
40s ribosomal protein s9 (22 kDa, Protein from Human)
40s ribosomal protein s4, x isoform (29 kDa, Protein from Human)
Probable dimethyladenosine transferase (35 kDa, Protein from Human)
Rna 3'-terminal phosphate cyclase-like protein (40 kDa, Protein from Human)
U3 small nucleolar ribonucleoprotein protein mpp10 (78 kDa, Protein from Human)
U3 small nucleolar rna-associated protein 6 homolog (70 kDa, Protein from Human)
Unassigned peptides (19 kDa, Protein from Human)
40s ribosomal protein s15a (14 kDa, Protein from Human)
U3 small nucleolar rna-interacting protein 2 (51 kDa, Protein from Human)
18s rrna (604 kDa, RNA from Human)
Adenosine-5'-triphosphate (507 Da, Ligand)
Ribosomal rna-processing protein 7 homolog a (32 kDa, Protein from Human)
Magnesium ion (24 Da, Ligand)
Guanosine-5'-triphosphate (523 Da, Ligand)
Small subunit processome component 20 homolog (318 kDa, Protein from Human)
Something about silencing protein 10 (54 kDa, Protein from Human)
Ddb1- and cul4-associated factor 13 (51 kDa, Protein from Human)
Heat repeat-containing protein 1 (242 kDa, Protein from Human)
Nucleolar complex protein 4 homolog (50 kDa, Protein from Human)
Exosome component 10 (100 kDa, Protein from Human)
40s ribosomal protein s19 (16 kDa, Protein from Human)
40s ribosomal protein s5 (22 kDa, Protein from Human)
Active regulator of sirt1 (15 kDa, Protein from Human)
Wd repeat-containing protein 3 (106 kDa, Protein from Human)
Wd repeat-containing protein 75 (94 kDa, Protein from Human)
40s ribosomal protein s27 (9 kDa, Protein from Human)
40s ribosomal protein s17 (15 kDa, Protein from Human)
Nhp2-like protein 1 (14 kDa, Protein from Human)
Periodic tryptophan protein 2 homolog (102 kDa, Protein from Human)
40s ribosomal protein s11 (18 kDa, Protein from Human)
Probable atp-dependent rna helicase dhx37 (129 kDa, Protein from Human)
40s ribosomal protein s12 (14 kDa, Protein from Human)
40s ribosomal protein s6 (28 kDa, Protein from Human)
Nucleolar protein 6 (127 kDa, Protein from Human)
U3 small nucleolar rna-associated protein 15 homolog (58 kDa, Protein from Human)
S-adenosyl-l-homocysteine (384 Da, Ligand)
Zinc ion (65 Da, Ligand)
40s ribosomal protein s23 (15 kDa, Protein from Human)
40s ribosomal protein s7 (22 kDa, Protein from Human)
40s ribosomal protein s18 (12 kDa, Protein from Human)
Rrna-processing protein fcf1 homolog (23 kDa, Protein from Human)
Rna-binding protein pno1 (27 kDa, Protein from Human)
U3 snorna (70 kDa, RNA from Human)
40s ribosomal protein s28 (7 kDa, Protein from Human)
40s ribosomal protein s13 (17 kDa, Protein from Human)
Nucleolar protein 58 (59 kDa, Protein from Human)
Rrp12-like protein (73 kDa, Protein from Human)
Wd repeat-containing protein 46 (68 kDa, Protein from Human)
40s ribosomal protein s16 (16 kDa, Protein from Human)
Ribosomal rna small subunit methyltransferase nep1 (26 kDa, Protein from Human)
40s ribosomal protein s3a (30 kDa, Protein from Human)
Bystin (33 kDa, Protein from Human)
Probable u3 small nucleolar rna-associated protein 11 (30 kDa, Protein from Human)
Wd repeat-containing protein 43 (74 kDa, Protein from Human)
U3 small nucleolar rna-associated protein 4 homolog (76 kDa, Protein from Human)
Transducin beta-like protein 3 (89 kDa, Protein from Human)
U3 small nucleolar ribonucleoprotein protein imp4 (33 kDa, Protein from Human)
Nucleolar protein 56 (66 kDa, Protein from Human)
U3 small nucleolar ribonucleoprotein protein imp3 (21 kDa, Protein from Human)

[Show more]

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Showing 1 - 3 of 3. Page 1 of 1

Display: Statistics

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Select database:

EMDB [3]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

Field: