EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

Edit your search query here and hit Return to execute it:

sample_name:"Glial cell line-derived neurotrophic factor" AND natural_source_ncbi_code:"7955"

Sort by: Download

Showing 1 - 4 of 4. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [4]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

EMD-18400

Download Map 3D View

GDNF/GFRa1 cell adhesion complex cryo-ET structure

Release date: Nov. 29, 2023
Resolution: 21.7 Å
EM Method: Subtomogram averaging

Houghton FM, Adams SE, Rios AS, Masino L, Purkiss AG, Briggs DC, Ledda F, McDonald NQ

Nat Commun (2023) 14 pp. 7551-7551 [ Pubmed: 37985758 DOI: doi:10.1038/s41467-023-43148-8 ]

Sample:

Gdnf/gfra1 cell adhesion complex (700 kDa, Complex from Danio rerio)
Glial cell line-derived neurotrophic factor (Protein from Danio rerio)
Gdnf family receptor alpha (Protein from Danio rerio)

EMD-18651

Download Map

GDNF/GFRa1 cell adhesion complex bridging between adhering liposomes.

Release date: Nov. 29, 2023
EM Method: Tomography

Houghton FM, Adams SE, Rios AS, Masino L, Purkiss AG, Briggs DC, Ledda F, McDonald NQ

Nat Commun (2023) 14 pp. 7551-7551 [ DOI: doi:10.1038/s41467-023-43148-8 Pubmed: 37985758 ]

Sample:

Gdnf/gfra1 cell adhesion complex assembled onto liposomes. (700 kDa, Complex from Danio rerio)
Gdnf family receptor alpha (Protein from Danio rerio)
Glial cell line-derived neurotrophic factor (Protein from Danio rerio)

EMD-11822

Download Map 3D View

RET/GDNF/GFRa1 extracellular complex Cryo-EM structure

Release date: Jan. 13, 2021
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7aml
Q-score: 0.33

Adams SE, Purkiss AG, Knowles PP, Nans A, Briggs DC, Borg A, Earl CP, Goodman KM, Nawrotek A, Borg AJ, McIntosh PB, Houghton FM, Kjaer S, McDonald NQ

Structure (2021) 29 pp. 694- [ DOI: doi:10.1016/j.str.2020.12.012 Pubmed: 33484636 ]

Sample:

2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Glial cell line-derived neurotrophic factor (11 kDa, Protein from Danio rerio)
Ternary complex of ret extracellular domain with gdnf and gfra1 ligand-coreceptor pair (240 kDa, Complex from Danio rerio)
Gdnf family receptor alpha (39 kDa, Protein from Danio rerio)
Proto-oncogene tyrosine-protein kinase receptor ret (69 kDa, Protein from Danio rerio)
Calcium ion (40 Da, Ligand)

[Show more]

EMD-2713

Download Map 3D View

Structure of the zebrafish RET tyrosine kinase extracellular domain

Release date: Oct. 1, 2014
Resolution: 26.0 Å
EM Method: Single-particle

Goodman K, Kjaer S, Beuron F, Knowles P, Nawrotek A, Burns E, Purkiss A, George R, Santoro M, Morris EP, McDonald NQ

Cell Rep (2014) 8 pp. 1894-1904 [ DOI: doi:10.1016/j.celrep.2014.08.040 Pubmed: 25242331 ]

Sample:

Gdnf receptor alpha (Protein from Danio rerio)
Reconstituted zebrafish retecd-gdnf-gfra1 ternary complex (240 kDa, Sample)
Glial-cell-line-derived neurotrophic factor (Protein from Danio rerio)
Ret receptor tyrosine kinase (83 kDa, Protein from Danio rerio)

[Show more]

Sort by: Download

Showing 1 - 4 of 4. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [4]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

Field: