To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Hgsnat (Complex from Homo sapiens)
- Decane (142 Da, Ligand)
- Heptane (100 Da, Ligand)
- Heparan-alpha-glucosaminide n-acetyltransferase (77 kDa, Protein from Homo sapiens)
- N-octane (114 Da, Ligand)
- Coenzyme a (767 Da, Ligand)
- ~{n}-[(2~{s},3~{r},4~{r},5~{s},6~{r})-6-(hydroxymethyl)-2-[[(2~{r},4~{r})-4-methyl-2-oxidanyl-3,4-dihydro-2~{h}-chromen-7-yl]oxy]-4,5-bis(oxidanyl)oxan-3-yl]ethanamide (383 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- Hexadecane (226 Da, Ligand)
structure of a membrane-integrated glycosyltransferase with inhibitor
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7xs6
Q-score: 0.572
Wu YN, Zhang M, Yang YZ, Ding XY, Liu XT, Zhang MJ, Yu HJ
To Be Published
- Chitin synthase 1 (130 kDa, Protein from Saccharomyces cerevisiae)
- Membrane-integrated glycosyltransferase (Complex from Saccharomyces cerevisiae)
- (2s)-{[(2s,3s,4s)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2r,3s,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid (non-preferred name) (495 Da, Ligand)
- (19r,22s)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9z)-hexadec-9-enoate (689 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Heptane (100 Da, Ligand)
Structure of human KCNQ4-ML213 complex with PIP2
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 7vnp
Q-score: 0.376
Zheng Y, Liu H, Chen Y, Dong S, Wang F, Wang S, Li GL, Shu Y, Xu F
Neuron (2022) 110 pp. 237- [ DOI: doi:10.1016/j.neuron.2021.10.029 Pubmed: 34767770 ]
- (1s,2s,4r)-n-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid (257 Da, Ligand)
- [(2r)-1-octadecanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8z)-icosa-5,8,11,14-tetraenoate (1 kDa, Ligand)
- Kcnq4-ml213 complex with pip2 (Complex from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Calmodulin-3 (16 kDa, Protein from Homo sapiens)
- Potassium voltage-gated channel subfamily kqt member 4,maltodextrin-binding protein (116 kDa, Protein from Escherichia coli (strain B / BL21-DE3))
Structure of human KCNQ4-ML213 complex in nanodisc
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 7vnq
Q-score: 0.238
Zheng Y, Liu H, Chen Y, Dong S, Wang F, Wang S, Li GL, Shu Y, Xu F
Neuron (2022) 110 pp. 237- [ DOI: doi:10.1016/j.neuron.2021.10.029 Pubmed: 34767770 ]
- Potassium voltage-gated channel subfamily kqt member 4,maltodextrin-binding protein (116 kDa, Protein from Escherichia coli (strain B / BL21-DE3))
- Potassium ion (39 Da, Ligand)
- Calmodulin-3 (16 kDa, Protein from Homo sapiens)
- (1s,2s,4r)-n-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid (257 Da, Ligand)
- Kcnq4-ml213 complex in nanodisc (Complex from Homo sapiens)
Structure of human KCNQ4-ML213 complex in digitonin
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7vnr
Q-score: 0.27
Zheng Y, Liu H, Chen Y, Dong S, Wang F, Wang S, Li GL, Shu Y, Xu F
Neuron (2022) 110 pp. 237- [ Pubmed: 34767770 DOI: doi:10.1016/j.neuron.2021.10.029 ]
- Calmodulin-3 (16 kDa, Protein from Homo sapiens)
- Potassium voltage-gated channel subfamily kqt member 4,maltodextrin-binding protein (116 kDa, Protein from Escherichia coli (strain B / BL21-DE3))
- (1s,2s,4r)-n-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid (257 Da, Ligand)
- Kcnq4-ml213 complex in digitonin (Complex from Homo sapiens)
- Potassium ion (39 Da, Ligand)
Cryo-EM reveals partially and fully assembled native glycine receptors,heteromeric pentamer
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7mly
Q-score: 0.49
Nature (2021) 599 pp. 513-517 [ DOI: doi:10.1038/s41586-021-04022-z Pubmed: 34555840 ]
- Pentane (72 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Native heteromeric glycine receptor bound with 3d1 fab (500 kDa, Complex)
- Hexane (86 Da, Ligand)
- Decane (142 Da, Ligand)
- Heptane (100 Da, Ligand)
- Glycine receptor beta (56 kDa, Protein from Pig)
- N-butane (58 Da, Ligand)
- N-octane (114 Da, Ligand)
- Glycine receptor alpha 1 (51 kDa, Protein from Pig)
- Pentadecane (212 Da, Ligand)
- Undecane (156 Da, Ligand)
- 3d1 fab (Complex from Rattus norvegicus)
- Nonane (128 Da, Ligand)
- Native heteromeric glycine receptor (Complex from Sus scrofa)
- Glycine (75 Da, Ligand)
- 3d1 fab light chain (11 kDa, Protein from Rattus norvegicus)
- 3d1 fab heavy chain (12 kDa, Protein from Rattus norvegicus)
Structure of human prestin in the presence of NaCl
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 7lgu
Q-score: 0.644
Ge J, Elferich J, Dehghani-Ghahnaviyeh S, Zhao Z, Meadows M, von Gersdorff H, Tajkhorshid E, Gouaux E
Cell (2021) 184 pp. 4669- [ DOI: doi:10.1016/j.cell.2021.07.034 Pubmed: 34390643 ]
- Cholesterol (386 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Hexane (86 Da, Ligand)
- Decane (142 Da, Ligand)
- Heptane (100 Da, Ligand)
- Protein structure bound with substrates and lipids (Complex from Homo sapiens)
- Chloride ion (35 Da, Ligand)
- Prestin (82 kDa, Protein from Homo sapiens)
- N-octane (114 Da, Ligand)
- Water (18 Da, Ligand)
- Tetradecane (198 Da, Ligand)
Structure of human Prestin in nanodisc in the presence of NaCl
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7lgw
Q-score: 0.567
Ge J, Elferich J, Dehghani-Ghahnaviyeh S, Zhao Z, Meadows M, von Gersdorff H, Tajkhorshid E, Gouaux E
Cell (2021) 184 pp. 4669- [ Pubmed: 34390643 DOI: doi:10.1016/j.cell.2021.07.034 ]
- Chloride ion (35 Da, Ligand)
- N-octane (114 Da, Ligand)
- Heptane (100 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Water (18 Da, Ligand)
- Hexane (86 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Protein structure bound with substrates and lipids (Complex from Homo sapiens)
- Prestin (82 kDa, Protein from Homo sapiens)
- Decane (142 Da, Ligand)