Cryo-EM map of HIV-1 Env 1059 complexed with N6 and 10-1074 Fabs
CH505 Disulfide Stapled SOSIP Bound to b12 Fab
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 8sxi
Q-score: 0.371
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
Sci Adv (2024) 10 pp. eadj0396-eadj0396 [ DOI: doi:10.1126/sciadv.adj0396 Pubmed: 38306419 ]
- B12 light chain (11 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp160 (51 kDa, Protein from Human immunodeficiency virus 1)
- Human immunodeficiency virus 1 (Virus from Human immunodeficiency virus 1)
- Hiv-1 gp41 (14 kDa, Protein from Human immunodeficiency virus 1)
- B12 heavy chain (14 kDa, Protein from Human immunodeficiency virus 1)
CH505 Disulfide Stapled SOSIP Bound to CH235.12 Fab
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8sxj
Q-score: 0.401
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
Sci Adv (2024) 10 pp. eadj0396-eadj0396 [ DOI: doi:10.1126/sciadv.adj0396 Pubmed: 38306419 ]
- Envelope glycoprotein gp160 (51 kDa, Protein from Human immunodeficiency virus 1)
- Ch235.12 light chain (11 kDa, Protein from Homo sapiens)
- Ch235.12 heavy chain (13 kDa, Protein from Homo sapiens)
- Human immunodeficiency virus 1 (Virus from Human immunodeficiency virus 1)
- Hiv-1 gp41 (14 kDa, Protein from Human immunodeficiency virus 1)
HIV-1 CA-SP1 subtomogram average with Relion4 from EMPIAR-10164 dataset, 3.2 A from 5 tomograms
Zivanov J, Oton J, Ke Z, von Kugelgen A, Pyle E, Qu K, Morado D, Castano-Diez D, Zanetti G, Bharat TAM, Briggs JAG, Scheres SHW
eLife (2022) 11 [ Pubmed: 36468689 DOI: doi:10.7554/eLife.83724 ]
- Human immunodeficiency virus 1 (74 kDa, Virus from Human immunodeficiency virus 1)
HIV-1 CA-SP1 subtomogram average with Relion4 from EMPIAR-10164 dataset, 3.0 A from the full dataset
Zivanov J, Oton J, Ke Z, von Kugelgen A, Pyle E, Qu K, Morado D, Castano-Diez D, Zanetti G, Bharat TAM, Briggs JAG, Scheres SHW
eLife (2022) 11 [ Pubmed: 36468689 DOI: doi:10.7554/eLife.83724 ]
- Human immunodeficiency virus 1 (74 kDa, Virus from Human immunodeficiency virus 1)
Sub-tomogram averaged structure of HIV-1 Envelope protein in native membrane
Resolution: 9.1 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7ska
Q-score: 0.067
Mangala Prasad V, Leaman DP, Lovendahl KN, Croft JT, Benhaim MA, Hodge EA, Zwick MB, Lee KK
Cell (2022) 185 pp. 641-653.e17 [ DOI: doi:10.1016/j.cell.2022.01.013 Pubmed: 35123651 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human immunodeficiency virus 1 (430 kDa, Virus from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Alpha-l-fucopyranose (164 Da, Ligand)
Asymmetric reconstruction of membrane-bound HIV Env from virus-like particles
Mangala Prasad V, Leaman DP, Lovendahl KN, Croft JT, Benhaim MA, Hodge EA, Zwick MB, Lee KK
Cell (2022) 185 pp. 641-653.e17 [ DOI: doi:10.1016/j.cell.2022.01.013 Pubmed: 35123651 ]