Matrix arm of active state CI from Q10-NADH dataset
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7vy8
Q-score: 0.645
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 30 kda subunit (24 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 9 kda subunit (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 13 kda-b subunit (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
Matrix arm of deactive state CI from Q10-NADH dataset
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7vya
Q-score: 0.597
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3 (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3 (5 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from pig)
- Respiratory complex i (Complex from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
Matrix arm of active state CI from Q10 dataset
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7vxp
Q-score: 0.615
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Acyl carrier protein, mitochondrial (10 kDa, Protein from pig)
- Complex i subunit b13 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
Matrix arm of deactive state CI from Q10 dataset
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7vxu
Q-score: 0.582
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Complex i-20kd (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from pig)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (78 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (53 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (23 kDa, Protein from pig)
Matrix arm of active state CI from Rotenone dataset
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7vyf
Q-score: 0.618
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (24 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Acyl carrier protein, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- (2r,6as,12as)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6ah)-one (394 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
Matrix arm of deactive state CI from Rotenone dataset
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7vyh
Q-score: 0.584
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (5 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from pig)
- Respiratory complex i (Complex from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
Matrix arm of active state CI from DQ-NADH dataset
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7vb7
Q-score: 0.693
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Flavin mononucleotide (456 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from Pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (5 kDa, Protein from Pig)
- Magnesium ion (24 Da, Ligand)
- Acyl carrier protein, mitochondrial (10 kDa, Protein from Pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from Pig)
- Iron/sulfur cluster (351 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from Pig)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from Pig)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from Pig)
- Respiratory complex i (Complex from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from Pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (24 kDa, Protein from Pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from Pig)
- Water (18 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from Pig)
Matrix arm of deactive state CI from DQ-NADH dataset
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7vbn
Q-score: 0.665
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (24 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Water (18 Da, Ligand)
- Acyl carrier protein, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
Matrix arm of active state CI from Rotenone-NADH dataset
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7vbz
Q-score: 0.661
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (24 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Water (18 Da, Ligand)
- Acyl carrier protein, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- (2r,6as,12as)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6ah)-one (394 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
Matrix arm of deactive state CI from rotenone-NADH dataset
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7vwj
Q-score: 0.631
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (24 kDa, Protein from pig)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Water (18 Da, Ligand)
- Acyl carrier protein, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Porcine respiratory complex i (Complex from Sus scrofa)