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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"IRON/SULFUR CLUSTER" AND resolution:[4 TO 5} AND sample_type:"protein" AND author_name:"Cramer P" AND structure_determination_method:"singleparticle" AND release_date:[2021-01-01T00:00:00Z TO 2021-12-31T23:59:59Z]

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EMDB [2]

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EMD-12610

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Human Mediator with RNA Polymerase II Pre-initiation complex

Release date: May 5, 2021
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7nvr
Q-score: 0.171

Aibara S, Schilbach S, Cramer P

Nature (2021) 594 pp. 124-128 [ Pubmed: 33902107 DOI: doi:10.1038/s41586-021-03554-8 ]

Sample:

Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Pig)
Pol complex and mediator of rna polymerase ii transcription (Complex from Homo sapiens)
Unassigned peptide (med29 or med30) (1 kDa, Protein from Trichoplusia ni)
Dna-directed rna polymerase (Complex from Sus scrofa)
Cdk-activating kinase assembly factor mat1 (35 kDa, Protein from Homo sapiens)
General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
General transcription factor iih subunit 1 (62 kDa, Protein from Homo sapiens)
General transcription factor iih subunit 3 (34 kDa, Protein from Homo sapiens)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 19 (26 kDa, Protein from Homo sapiens)
Rna polymerase ii subunit k (7 kDa, Protein from Pig)
Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Pig)
General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 30 (20 kDa, Protein from Homo sapiens)
Unassigned peptide, likely tfiie-beta (1 kDa, Protein from Homo sapiens)
Transcription initiation factors (Complex from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 11 (13 kDa, Protein from Homo sapiens)
Human mediator with rna polymerase ii pre-initiation complex (Complex)
Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Pig)
Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Pig)
Mediator of rna polymerase ii transcription subunit 8 (29 kDa, Protein from Homo sapiens)
Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 20 (23 kDa, Protein from Homo sapiens)
Unassigned peptide, likely xpb (698 Da, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 14 (160 kDa, Protein from Homo sapiens)
General transcription factor iih subunit 2 (44 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 22 (22 kDa, Protein from Homo sapiens)
Template (32 kDa, DNA from Human mastadenovirus C)
Mediator of rna polymerase ii transcription subunit 10 (15 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Pig)
Mediator of rna polymerase ii transcription subunit 28 (19 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Mediator of rna polymerase ii transcription subunit 6 (28 kDa, Protein from Homo sapiens)
Rpol4c domain-containing protein (16 kDa, Protein from Pig)
Transcription initiation factor iia subunit 1 (41 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 9 (16 kDa, Protein from Homo sapiens)
Rna_pol_l_2 domain-containing protein (13 kDa, Protein from Pig)
Nt and template (Complex from Human mastadenovirus C)
Cyclin-dependent kinase 7 (39 kDa, Protein from Homo sapiens)
Unassigned peptide (med14) (1 kDa, Protein from Homo sapiens)
Unassigned peptide (med17) (954 Da, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
Tfiih basal transcription factor complex helicase xpd subunit (87 kDa, Protein from Homo sapiens)
General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 7 (27 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
Dna-directed rna polymerase subunit (217 kDa, Protein from Pig)
Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Pig)
Nt (32 kDa, DNA from Human mastadenovirus C)
General transcription and dna repair factor iih helicase subunit xpb (89 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 31 (15 kDa, Protein from Homo sapiens)
Unassigned peptide (med29 or med30) (1 kDa, Protein from Trichoplusia ni)
Cyclin-h (37 kDa, Protein from Homo sapiens)
General transcription factor iih subunit 5 (8 kDa, Protein from Homo sapiens)
Unassigned peptide (med6) (1 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 18 (23 kDa, Protein from Homo sapiens)
Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 21 (15 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 27 (35 kDa, Protein from Homo sapiens)
Unassigned peptide (med29 or med30) (1 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Pig)
Dna-directed rna polymerase subunit beta (134 kDa, Protein from Pig)
Mediator of rna polymerase ii transcription subunit 4 (29 kDa, Protein from Homo sapiens)
General transcription factor iih subunit 4 (52 kDa, Protein from Homo sapiens)
Mediator of rna polymerase ii transcription subunit 17 (72 kDa, Protein from Homo sapiens)
Unassigned peptides (med29 or med30) (Complex from Trichoplusia ni)

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EMD-12615

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TFIIH in a pre-translocated state (without ADP-BeF3)

Release date: May 5, 2021
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7nvw
Q-score: 0.279

Aibara S, Schilbach S, Cramer P

Nature (2021) 594 pp. 124-128 [ Pubmed: 33902107 DOI: doi:10.1038/s41586-021-03554-8 ]

Sample:

Cdk-activating kinase assembly factor mat1 (35 kDa, Protein from Homo sapiens)
General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
General transcription factor iih subunit 1 (62 kDa, Protein from Homo sapiens)
Template dna (32 kDa, DNA from Human mastadenovirus C)
General transcription and dna repair factor iih helicase subunit xpb (89 kDa, Protein from Homo sapiens)
General transcription factor iih subunit 4 (52 kDa, Protein from Homo sapiens)
General transcription factor iih subunit 3 (34 kDa, Protein from Homo sapiens)
General transcription factor iih subunit 5 (8 kDa, Protein from Homo sapiens)
Tfiih (without adp-bef3) (490 kDa, Complex)
Zinc ion (65 Da, Ligand)
Unassigned peptide, likely xpb (698 Da, Protein from Homo sapiens)
Non-template dna (32 kDa, DNA from Human mastadenovirus C)
General transcription factor iih subunit 2 (44 kDa, Protein from Homo sapiens)
Tfiih basal transcription factor complex helicase xpd subunit (87 kDa, Protein from Homo sapiens)
Unassigned peptide, likely tfiie-beta (1 kDa, Protein from Homo sapiens)

[Show more]

Sort by: Download

Showing 1 - 2 of 2. Page 1 of 1

Display: Statistics

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Select database:

EMDB [2]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

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