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sample_name:"IRON/SULFUR CLUSTER" AND xref_links:"chembl" AND assembly_molecular_weight:{2000000 TO 5000000]
In-situ structure of typeA supercomplex with lipids in respiratory chain (composite)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
Sample:
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform x1 (13 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Sus scrofa)
- Sodium ion (22 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Sus scrofa)
- Dinuclear copper ion (127 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 1 (57 kDa, Protein from Sus scrofa)
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofa)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Sus scrofa)
- Iron/sulfur cluster (351 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- (1s)-2-{[{[(2r)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (751 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (48 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit ab1 (17 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 4 (19 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7a1, mitochondrial (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Sus scrofa)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sus scrofa)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Sus scrofa)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 6a2 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a13 (16 kDa, Protein from Sus scrofa)
- Cytochrome c1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from Sus scrofa)
- N-acetylalanine (131 Da, Ligand)
- Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome c oxidase subunit 7b (9 kDa, Protein from Sus scrofa)
- N-acetylmethionine (191 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sus scrofa)
- Heme-a (852 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a9 (42 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [sus scrofa] (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Sus scrofa)
- Flavin mononucleotide (456 Da, Ligand)
- Cytochrome c oxidase subunit ndufa4 (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from Sus scrofa)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sus scrofa)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(stearoyloxy)methyl]ethyl (5e,8e,11e,14e)-icosa-5,8,11,14-tetraenoate (768 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein (7 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (28 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 8 (7 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Sus scrofa)
- (7r,17e,20e)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide (759 Da, Ligand)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Sus scrofa)
In-situ structure of typeB supercomplex in respiratory chain (composite)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
Sample:
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform x1 (13 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Sus scrofa)
- Sodium ion (22 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Sus scrofa)
- Dinuclear copper ion (127 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein 53 complext iii (6 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 1 (57 kDa, Protein from Sus scrofa)
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofa)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (48 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit ab1 (17 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (54 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 4 (19 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7a1, mitochondrial (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Sus scrofa)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sus scrofa)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Sus scrofa)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 6a2 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a13 (16 kDa, Protein from Sus scrofa)
- Cytochrome c1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from Sus scrofa)
- N-acetylalanine (131 Da, Ligand)
- Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome c oxidase subunit 7b (9 kDa, Protein from Sus scrofa)
- N-acetylmethionine (191 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sus scrofa)
- Heme-a (852 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a9 (42 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [sus scrofa] (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Sus scrofa)
- Flavin mononucleotide (456 Da, Ligand)
- Cytochrome c oxidase subunit ndufa4 (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from Sus scrofa)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sus scrofa)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(stearoyloxy)methyl]ethyl (5e,8e,11e,14e)-icosa-5,8,11,14-tetraenoate (768 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (28 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 8 (7 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Sus scrofa)
- Cholic acid (408 Da, Ligand)
- (7r,17e,20e)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide (759 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Sus scrofa)
In-situ structure of typeO supercomplex in respiratory chain (composite)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
Sample:
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform x1 (13 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Sus scrofa)
- Sodium ion (22 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Sus scrofa)
- Dinuclear copper ion (127 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 1 (57 kDa, Protein from Sus scrofa)
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofa)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein 53 complext iii (7 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (48 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit ab1 (17 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (54 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 4 (19 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7a1, mitochondrial (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Sus scrofa)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sus scrofa)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Sus scrofa)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 6a2 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a13 (16 kDa, Protein from Sus scrofa)
- Cytochrome c1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from Sus scrofa)
- N-acetylalanine (131 Da, Ligand)
- Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome c oxidase subunit 7b (9 kDa, Protein from Sus scrofa)
- N-acetylmethionine (191 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sus scrofa)
- Heme-a (852 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a9 (42 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [sus scrofa] (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Sus scrofa)
- Flavin mononucleotide (456 Da, Ligand)
- Cytochrome c oxidase subunit ndufa4 (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from Sus scrofa)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sus scrofa)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(stearoyloxy)methyl]ethyl (5e,8e,11e,14e)-icosa-5,8,11,14-tetraenoate (768 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (28 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 8 (7 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Sus scrofa)
- (7r,17e,20e)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide (759 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Sus scrofa)
In-situ structure of typeX supercomplex in respiratory chain (composite)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
Sample:
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform x1 (13 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Sus scrofa)
- Sodium ion (22 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Sus scrofa)
- Dinuclear copper ion (127 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sus scrofa)
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofaSus scrofa)
- Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 1 (57 kDa, Protein from Sus scrofa)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Iron/sulfur cluster (351 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (48 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit ab1 (17 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (54 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 4 (19 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7a1, mitochondrial (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Sus scrofa)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sus scrofa)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Sus scrofa)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 6a2 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a13 (16 kDa, Protein from Sus scrofa)
- Cytochrome c1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from Sus scrofa)
- N-acetylalanine (131 Da, Ligand)
- Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome c oxidase subunit 7b (9 kDa, Protein from Sus scrofa)
- N-acetylmethionine (191 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sus scrofa)
- Heme-a (852 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a9 (42 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [sus scrofa] (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Sus scrofa)
- Flavin mononucleotide (456 Da, Ligand)
- Cytochrome c oxidase subunit ndufa4 (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from Sus scrofa)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein (7 kDa, Protein from Sus scrofa)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(stearoyloxy)methyl]ethyl (5e,8e,11e,14e)-icosa-5,8,11,14-tetraenoate (768 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (28 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 8 (7 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Sus scrofa)
- (7r,17e,20e)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide (759 Da, Ligand)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Sus scrofa)
CS respirasome from murine liver
Release date: April 24, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8pw5
Q-score: 0.465
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8pw5
Q-score: 0.465
Nat Struct Mol Biol (2024) [ Pubmed: 38575788 DOI: doi:10.1038/s41594-024-01255-0 ]
Sample:
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Mus musculus)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
- Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Mus musculus)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
- Heme-a (852 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Cytochrome c oxidase subunit 8b, mitochondrial (7 kDa, Protein from Mus musculus)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
- Cardiolipin (1 kDa, Ligand)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Mus musculus)
- Sodium ion (22 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
- Potassium ion (39 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
- Heme c (618 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Mus musculus)
- Sc respirasome from murine liver (1 MDa, Complex from Mus musculus)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Mus musculus)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
- Cox7a2l protein (12 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
- 2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
- Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Mus musculus)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Mus musculus)
- Tristearoylglycerol (891 Da, Ligand)
- Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
- Cytochrome c oxidase subunit 2 (25 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
- Magnesium ion (24 Da, Ligand)
- Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Mus musculus)
- Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Mus musculus)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome b (43 kDa, Protein from Mus musculus)
- Cytochrome c oxidase subunit 7a2, mitochondrial (9 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Mus musculus)
- Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Mus musculus)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
- Dinuclear copper ion (127 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Mus musculus)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Mus musculus)
- Cytochrome c oxidase subunit 6a2, mitochondrial (10 kDa, Protein from Mus musculus)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
- Cytochrome c oxidase subunit 1 (56 kDa, Protein from Mus musculus)
- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Mus musculus)
Cryo-EM structure of Euglena gracilis super-complex I+III2+IV, composite
Release date: Feb. 28, 2024
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8iuf
Q-score: 0.615
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8iuf
Q-score: 0.615
He Z, Wu M, Tian H, Wang L, Hu Y, Han F, Zhou J, Wang Y, Zhou L
Nat Commun (2024) 15 pp. 1628-1628 [ DOI: doi:10.1038/s41467-024-46018-z Pubmed: 38388527 ]
Sample:
- Coxeg7 (35 kDa, Protein from Euglena gracilis)
- Poly(unk) (1 kDa, Protein from Euglena gracilis)
- Nd4l (19 kDa, Protein from Euglena gracilis)
- Ndufa11 (32 kDa, Protein from Euglena gracilis)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Ndueg9 (18 kDa, Protein from Euglena gracilis)
- Ndufa3 (14 kDa, Protein from Euglena gracilis)
- Nduca3 (28 kDa, Protein from Euglena gracilis)
- Ndufb4 (19 kDa, Protein from Euglena gracilis)
- Ndufa12 (33 kDa, Protein from Euglena gracilis)
- Ubiquinol-cytochrome-c reductase complex subunit ix, mitochondrial (11 kDa, Protein from Euglena gracilis)
- Cox4 (20 kDa, Protein from Euglena gracilis)
- Ndufab1-alpha (14 kDa, Protein from Euglena gracilis)
- Ndufa13 (22 kDa, Protein from Euglena gracilis)
- Cytochrome c oxidase subunit 2 (22 kDa, Protein from Euglena gracilis)
- Nduca1 (48 kDa, Protein from Euglena gracilis)
- Coxeg9 (31 kDa, Protein from Euglena gracilis)
- Ndueg7 (26 kDa, Protein from Euglena gracilis)
- Ndueg10 (14 kDa, Protein from Euglena gracilis)
- Euglena gracilis respirasome supercomplex i+iii2+iv (2 MDa, Complex from Euglena gracilis)
- Ndufs7 (22 kDa, Protein from Euglena gracilis)
- Ndufs5 (14 kDa, Protein from Euglena gracilis)
- Uqcr10 (17 kDa, Protein from Euglena gracilis)
- Heme-a (852 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Cox6a (13 kDa, Protein from Euglena gracilis)
- Ndufb6 (10 kDa, Protein from Euglena gracilis)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome c oxidase subunit 1 (55 kDa, Protein from Euglena gracilis)
- 1,2-dilauroyl-sn-glycero-3-phosphate (535 Da, Ligand)
- Cox6b-1 (32 kDa, Protein from Euglena gracilis)
- Coxeg6 (8 kDa, Protein from Euglena gracilis)
- Ndufa6 (48 kDa, Protein from Euglena gracilis)
- Ndufb10 (17 kDa, Protein from Euglena gracilis)
- Ubiquinone-10 (863 Da, Ligand)
- Mpp-beta (53 kDa, Protein from Euglena gracilis)
- Cardiolipin (1 kDa, Ligand)
- Nd2b (15 kDa, Protein from Euglena gracilis)
- Coxeg10 (10 kDa, Protein from Euglena gracilis)
- Ndueg13 (17 kDa, Protein from Euglena gracilis)
- Cox5b-2 (19 kDa, Protein from Euglena gracilis)
- Nd1 (79 kDa, Protein from Euglena gracilis)
- Ndufv1 (57 kDa, Protein from Euglena gracilis)
- Potassium ion (39 Da, Ligand)
- Ndueg2 (51 kDa, Protein from Euglena gracilis)
- Ndufb2 (17 kDa, Protein from Euglena gracilis)
- Cox5c (23 kDa, Protein from Euglena gracilis)
- Nduca2 (28 kDa, Protein from Euglena gracilis)
- Heme c (618 Da, Ligand)
- Cytochrome b (42 kDa, Protein from Euglena gracilis)
- Ndueg3 (63 kDa, Protein from Euglena gracilis)
- Ndufb3 (6 kDa, Protein from Euglena gracilis)
- Ndueg11 (11 kDa, Protein from Euglena gracilis)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nd2a (35 kDa, Protein from Euglena gracilis)
- Flavin mononucleotide (456 Da, Ligand)
- Ndufb5 (15 kDa, Protein from Euglena gracilis)
- Ndufb11 (13 kDa, Protein from Euglena gracilis)
- Coxeg5 (19 kDa, Protein from Euglena gracilis)
- Uqcrq (9 kDa, Protein from Euglena gracilis)
- Ndueg5 (29 kDa, Protein from Euglena gracilis)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (56 kDa, Protein from Euglena gracilis)
- Ndufs2 (45 kDa, Protein from Euglena gracilis)
- Ndufa2 (21 kDa, Protein from Euglena gracilis)
- Ndufc2 (22 kDa, Protein from Euglena gracilis)
- Nd3 (34 kDa, Protein from Euglena gracilis)
- Ndufs1b (59 kDa, Protein from Euglena gracilis)
- Ndufs1a (43 kDa, Protein from Euglena gracilis)
- Ndufa9 (54 kDa, Protein from Euglena gracilis)
- Uqcrfs1 (27 kDa, Protein from Euglena gracilis)
- Ndufv2 (25 kDa, Protein from Euglena gracilis)
- Coxeg8 (24 kDa, Protein from Euglena gracilis)
- Cox7a (20 kDa, Protein from Euglena gracilis)
- Uqcrb (27 kDa, Protein from Euglena gracilis)
- Ndueg4 (41 kDa, Protein from Euglena gracilis)
- Nd5 (68 kDa, Protein from Euglena gracilis)
- Magnesium ion (24 Da, Ligand)
- Ndueg8 (23 kDa, Protein from Euglena gracilis)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Coxeg1 (27 kDa, Protein from Euglena gracilis)
- Ndufs8 (24 kDa, Protein from Euglena gracilis)
- Ndufs3 (32 kDa, Protein from Euglena gracilis)
- Copper (ii) ion (63 Da, Ligand)
- Ndufs4 (23 kDa, Protein from Euglena gracilis)
- Euglena gracilis respirasome supercomplex i+iii2+iv (Complex from Euglena gracilis)
- Ndueg11 (11 kDa, Protein from Euglena gracilis)
- Coxeg3 (16 kDa, Protein from Euglena gracilis)
- Coxeg4 (19 kDa, Protein from Euglena gracilis)
- Ndufa5 (20 kDa, Protein from Euglena gracilis)
- Cox7c (19 kDa, Protein from Euglena gracilis)
- Ndueg1 (53 kDa, Protein from Euglena gracilis)
- Ndufab1-beta (14 kDa, Protein from Euglena gracilis)
- Ndufa7 (16 kDa, Protein from Euglena gracilis)
- Ndufb8 (20 kDa, Protein from Euglena gracilis)
- Ndufs6 (17 kDa, Protein from Euglena gracilis)
- Uqcrh (8 kDa, Protein from Euglena gracilis)
- Cytochrome c1, heme protein (27 kDa, Protein from Euglena gracilis)
- O-[(s)-hydroxy{[(2s)-2-hydroxy-3-(octadec-9-enoyloxy)propyl]oxy}phosphoryl]-l-serine (523 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ndufb9 (18 kDa, Protein from Euglena gracilis)
- Ndufa8 (25 kDa, Protein from Euglena gracilis)
- Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial (51 kDa, Protein from Euglena gracilis)
- Ndufb7 (12 kDa, Protein from Euglena gracilis)
- Uqcr9 (6 kDa, Protein from Euglena gracilis)
- Ndufx (37 kDa, Protein from Euglena gracilis)
- Ndufa1 (15 kDa, Protein from Euglena gracilis)
- Ndueg6 (43 kDa, Protein from Euglena gracilis)
- Putative nadh dehydrogenase subunit 6 (19 kDa, Protein from Euglena gracilis)
Terminating ribosome with SRI-41315
Release date: Dec. 27, 2023
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8scb
Q-score: 0.589
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8scb
Q-score: 0.589
Coelho JPL, Yip MCJ, Oltion K, Taunton J, Shao S
To Be Published
Sample:
- Es12 (14 kDa, Protein from Oryctolagus cuniculus)
- Us12 (15 kDa, Protein from Oryctolagus cuniculus)
- El32 (15 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
- Es6 (28 kDa, Protein from Oryctolagus cuniculus)
- Us4 (22 kDa, Protein from Oryctolagus cuniculus)
- Es30 (14 kDa, Protein from Oryctolagus cuniculus)
- Us7 (22 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s acidic ribosomal protein p0 (34 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l12 (17 kDa, Protein from Oryctolagus cuniculus)
- Water (18 Da, Ligand)
- Ribosomal protein l18 (21 kDa, Protein from Oryctolagus cuniculus)
- Us17 (18 kDa, Protein from Oryctolagus cuniculus)
- El28 (15 kDa, Protein from Oryctolagus cuniculus)
- Iron/sulfur cluster (351 Da, Ligand)
- Ul24 (17 kDa, Protein from Oryctolagus cuniculus)
- El39 (6 kDa, Protein from Oryctolagus cuniculus)
- El31 (14 kDa, Protein from Oryctolagus cuniculus)
- Es19 (16 kDa, Protein from Oryctolagus cuniculus)
- El42 (12 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s3 (26 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (26 kDa, Protein from Oryctolagus cuniculus)
- El43 (10 kDa, Protein from Oryctolagus cuniculus)
- Us2 (sa) (32 kDa, Protein from Oryctolagus cuniculus)
- Ubiquitin a-52 residue ribosomal protein fusion product 1 (10 kDa, Protein from Oryctolagus cuniculus)
- E_trna (24 kDa, RNA from Oryctolagus cuniculus)
- 5.8s_rrna (50 kDa, RNA from Oryctolagus cuniculus)
- El22 (14 kDa, Protein from Oryctolagus cuniculus)
- Es21 (9 kDa, Protein from Oryctolagus cuniculus)
- Us8 (14 kDa, Protein from Oryctolagus cuniculus)
- Us5 (31 kDa, Protein from Oryctolagus cuniculus)
- Es27 (9 kDa, Protein from Oryctolagus cuniculus)
- Us11 (18 kDa, Protein from Oryctolagus cuniculus)
- El23 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- Terminating rabbit ribosome (4 MDa, Complex from Oryctolagus cuniculus)
- P_trna (24 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- El20 (20 kDa, Protein from Oryctolagus cuniculus)
- Es17 (15 kDa, Protein from Oryctolagus cuniculus)
- Mrna (63 kDa, RNA from Homo sapiens)
- Ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
- Us14 (6 kDa, Protein from Oryctolagus cuniculus)
- Es8 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
- 28s_rrna (1 MDa, RNA from Oryctolagus cuniculus)
- Eukaryotic peptide chain release factor subunit 1 (51 kDa, Protein from Homo sapiens)
- Es25 (13 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- Ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- Us9 (16 kDa, Protein from Oryctolagus cuniculus)
- Receptor for activated c kinase 1 (rack1) (35 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- 40s ribosomal protein s26 (13 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- El13 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
- Es28 (7 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- 5s_rrna (38 kDa, RNA from Oryctolagus cuniculus)
- Es4 (s4 x isoform) (29 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
- El35 (14 kDa, Protein from Oryctolagus cuniculus)
- Es31 (18 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
- El41 (3 kDa, Protein from Oryctolagus cuniculus)
- Es7 (22 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- Us10 (13 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l8 (28 kDa, Protein from Oryctolagus cuniculus)
- Es1 (30 kDa, Protein from Oryctolagus cuniculus)
- Atp binding cassette subfamily e member 1 (67 kDa, Protein from Oryctolagus cuniculus)
- El30 (12 kDa, Protein from Oryctolagus cuniculus)
- Nc (13 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Us13 (17 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
- Us19 (17 kDa, Protein from Oryctolagus cuniculus)
- El21 (18 kDa, Protein from Oryctolagus cuniculus)
- 18s_rrna (603 kDa, RNA from Oryctolagus cuniculus)
- 40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
- Ul22 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l7 (29 kDa, Protein from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Oryctolagus cuniculus)
- Us15 (17 kDa, Protein from Oryctolagus cuniculus)
- S10_plectin domain-containing protein (18 kDa, Protein from Oryctolagus cuniculus)
- (2s,4as)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3h,4ah)-dione (359 Da, Ligand)
Release date: Dec. 6, 2023
Resolution: 5.47 Å
EM Method: Single-particle
Fitted PDBs: 8wak
Q-score: 0.079
Resolution: 5.47 Å
EM Method: Single-particle
Fitted PDBs: 8wak
Q-score: 0.079
Chen X, Liu W, Wang Q, Wang X, Ren Y, Qu X, Li W, Xu Y
Science (2023) 382 pp. eadi5120-eadi5120 [ DOI: doi:10.1126/science.adi5120 Pubmed: 38127763 ]
Sample:
- Transcription initiation factor tfiid subunit 11 (23 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 13 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
- Rna polymerase ii (Complex from Sus scrofa)
- Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
- Cdk-activating kinase assembly factor mat1 (35 kDa, Protein from Homo sapiens)
- Tfiid (Complex from Homo sapiens)
- General transcription factor iih subunit 1 (62 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 3 (34 kDa, Protein from Homo sapiens)
- Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
- General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
- General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 2 (137 kDa, Protein from Homo sapiens)
- Alpha-amanitin (Complex from Amanita phalloides)
- Dna-directed rna polymerase ii subunit rpb11-a (13 kDa, Protein from Sus scrofa)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
- Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 2 (44 kDa, Protein from Homo sapiens)
- Structure of transcribing complex 2 (tc2), the initially transcribing complex with pol ii positioned 2nt downstream of tss (Complex)
- Rna (Complex from synthetic construct)
- Zinc ion (65 Da, Ligand)
- Tfiie (Complex from Homo sapiens)
- Dna-directed rna polymerase subunit (217 kDa, Protein from Sus scrofa)
- General transcription and dna repair factor iih helicase subunit xpd (87 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Sus scrofa)
- Dna (Complex from synthetic construct)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Sus scrofa)
- Non-template dna (30 kDa, DNA from synthetic construct)
- Dna-directed rna polymerase subunit beta (134 kDa, Protein from Sus scrofa)
- Tfiib (Complex from Homo sapiens)
- Template dna (30 kDa, DNA from synthetic construct)
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
- Rna (847 Da, RNA from synthetic construct)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
- Transcription initiation factor tfiid subunit 3 (103 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 7 (40 kDa, Protein from Homo sapiens)
- General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Sus scrofa)
- General transcription and dna repair factor iih helicase subunit xpb (89 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
- Tfiih (Complex from Homo sapiens)
- Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 5 (8 kDa, Protein from Homo sapiens)
- Tfiia (Complex from Homo sapiens)
- Tfiif (Complex from Homo sapiens)
- Alpha-amanitin (939 Da, Protein from Amanita phalloides)
- Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
- Rpb12 (7 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
- Transcription initiation factor iia beta chain (41 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 4 (52 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 1 (212 kDa, Protein from Homo sapiens)
- [[(2~{s},3~{r},4~{s},5~{r})-5-(2-azanyl-6-oxidanylidene-3~{h}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate (537 Da, Ligand)
Release date: Dec. 6, 2023
Resolution: 8.52 Å
EM Method: Single-particle
Fitted PDBs: 8wal
Q-score: 0.084
Resolution: 8.52 Å
EM Method: Single-particle
Fitted PDBs: 8wal
Q-score: 0.084
Chen X, Liu W, Wang Q, Wang X, Ren Y, Qu X, Li W, Xu Y
Science (2023) 382 pp. eadi5120-eadi5120 [ DOI: doi:10.1126/science.adi5120 Pubmed: 38127763 ]
Sample:
- Transcription initiation factor tfiid subunit 11 (23 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 13 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
- Rna polymerase ii (Complex from Sus scrofa)
- Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
- Cdk-activating kinase assembly factor mat1 (35 kDa, Protein from Homo sapiens)
- Tfiid (Complex from Homo sapiens)
- General transcription factor iih subunit 1 (62 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 3 (34 kDa, Protein from Homo sapiens)
- Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
- General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
- General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 2 (137 kDa, Protein from Homo sapiens)
- Alpha-amanitin (Complex from Amanita phalloides)
- Dna-directed rna polymerase ii subunit rpb11-a (13 kDa, Protein from Sus scrofa)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
- Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
- Rna (1 kDa, RNA from synthetic construct)
- General transcription factor iih subunit 2 (44 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Rna (Complex from synthetic construct)
- Tfiie (Complex from Homo sapiens)
- Dna-directed rna polymerase subunit (217 kDa, Protein from Sus scrofa)
- General transcription and dna repair factor iih helicase subunit xpd (87 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Sus scrofa)
- Dna (Complex from synthetic construct)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Sus scrofa)
- Non-template dna (30 kDa, DNA from synthetic construct)
- Dna-directed rna polymerase subunit beta (134 kDa, Protein from Sus scrofa)
- Tfiib (Complex from Homo sapiens)
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
- Template dna (30 kDa, DNA from synthetic construct)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
- Transcription initiation factor tfiid subunit 3 (103 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 7 (40 kDa, Protein from Homo sapiens)
- General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Sus scrofa)
- General transcription and dna repair factor iih helicase subunit xpb (89 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
- Tfiih (Complex from Homo sapiens)
- Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 5 (8 kDa, Protein from Homo sapiens)
- Structure of transcribing complex 3 (tc3), the initially transcribing complex with pol ii positioned 3nt downstream of tss (Complex)
- Tfiia (Complex from Homo sapiens)
- Tfiif (Complex from Homo sapiens)
- Alpha-amanitin (939 Da, Protein from Amanita phalloides)
- Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
- Rpb12 (7 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
- Transcription initiation factor iia beta chain (41 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 4 (52 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 1 (212 kDa, Protein from Homo sapiens)
- [[(2~{s},3~{r},4~{s},5~{r})-5-(2-azanyl-6-oxidanylidene-3~{h}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate (537 Da, Ligand)
Release date: Dec. 6, 2023
Resolution: 6.07 Å
EM Method: Single-particle
Fitted PDBs: 8wan
Q-score: 0.078
Resolution: 6.07 Å
EM Method: Single-particle
Fitted PDBs: 8wan
Q-score: 0.078
Chen X, Liu W, Wang Q, Wang X, Ren Y, Qu X, Li W, Xu Y
Science (2023) 382 pp. eadi5120-eadi5120 [ Pubmed: 38127763 DOI: doi:10.1126/science.adi5120 ]
Sample:
- Template dna (30 kDa, DNA from synthetic construct)
- Alpha-amanitin (939 Da, Protein from Amanita phalloides)
- Rna polymerase ii (Complex from Sus scrofa)
- Tfiie (Complex from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
- Non-template dna (30 kDa, DNA from synthetic construct)
- General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
- Rna (Complex from synthetic construct)
- Transcription initiation factor tfiid subunit 3 (103 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Sus scrofa)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
- Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase subunit (217 kDa, Protein from Sus scrofa)
- Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
- Tfiih (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
- General transcription factor iih subunit 5 (8 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 7 (40 kDa, Protein from Homo sapiens)
- Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
- Alpha-amanitin (Complex from Amanita phalloides)
- Transcription initiation factor tfiid subunit 2 (137 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Sus scrofa)
- Cdk-activating kinase assembly factor mat1 (35 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase subunit beta (134 kDa, Protein from Sus scrofa)
- Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
- Dna (Complex from synthetic construct)
- Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- General transcription factor iih subunit 1 (62 kDa, Protein from Homo sapiens)
- Structure of transcribing complex 4 (tc4), the initially transcribing complex with pol ii positioned 4nt downstream of tss (Complex)
- Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
- General transcription and dna repair factor iih helicase subunit xpb (89 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Sus scrofa)
- General transcription factor iih subunit 4 (52 kDa, Protein from Homo sapiens)
- Tfiib (Complex from Homo sapiens)
- Transcription initiation factor tfiid subunit 13 (14 kDa, Protein from Homo sapiens)
- General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Rpb12 (7 kDa, Protein from Sus scrofa)
- Transcription initiation factor tfiid subunit 1 (212 kDa, Protein from Homo sapiens)
- Transcription initiation factor iia beta chain (41 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Sus scrofa)
- General transcription and dna repair factor iih helicase subunit xpd (87 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
- Transcription initiation factor tfiid subunit 11 (23 kDa, Protein from Homo sapiens)
- General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 3 (34 kDa, Protein from Homo sapiens)
- Tfiid (Complex from Homo sapiens)
- Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
- [[(2~{s},3~{r},4~{s},5~{r})-5-(2-azanyl-6-oxidanylidene-3~{h}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate (537 Da, Ligand)
- Tfiif (Complex from Homo sapiens)
- Rna (1 kDa, RNA from synthetic construct)
- General transcription factor iih subunit 2 (44 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb11-a (13 kDa, Protein from Sus scrofa)
- Tfiia (Complex from Homo sapiens)