Cryo-EM structure of human Elp123 in complex with tRNA, acetyl-CoA, 5'-deoxyadenosine and methionine
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8ptx
Q-score: 0.441
Abbassi NE, Jaciuk M, Scherf D, Bohnert P, Rau A, Hammermeister A, Rawski M, Indyka P, Wazny G, Chramiec-Glabik A, Dobosz D, Skupien-Rabian B, Jankowska U, Rappsilber J, Schaffrath R, Lin TY, Glatt S
Nat Commun (2024) 15 pp. 4094-4094 [ DOI: doi:10.1038/s41467-024-48251-y Pubmed: 38750017 ]
- Iron/sulfur cluster (351 Da, Ligand)
- Human elp123 in complex with glutamine trna, acetyl-coa, 5'-deoxyadenosine and methionine (635 kDa, Complex from Homo sapiens)
- Trna gln (24 kDa, RNA from Homo sapiens)
- Elongator complex protein 1 (150 kDa, Protein from Homo sapiens)
- Elongator complex protein 2 (92 kDa, Protein from Homo sapiens)
- Acetyl coenzyme *a (809 Da, Ligand)
- 5'-deoxyadenosine (251 Da, Ligand)
- Elongator complex protein 3 (65 kDa, Protein from Homo sapiens)
- Methionine (149 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of human Elp123 in complex with 5'-deoxyadenosine and methionine
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 8pty
Q-score: 0.487
Abbassi NE, Jaciuk M, Scherf D, Bohnert P, Rau A, Hammermeister A, Rawski M, Indyka P, Wazny G, Chramiec-Glabik A, Dobosz D, Skupien-Rabian B, Jankowska U, Rappsilber J, Schaffrath R, Lin TY, Glatt S
Nat Commun (2024) 15 pp. 4094-4094 [ DOI: doi:10.1038/s41467-024-48251-y Pubmed: 38750017 ]
- Iron/sulfur cluster (351 Da, Ligand)
- Human elp123 in complex with 5'-deoxyadenosine and methionine (610 kDa, Complex from Homo sapiens)
- Elongator complex protein 3 (65 kDa, Protein from Homo sapiens)
- Elongator complex protein 1 (150 kDa, Protein from Homo sapiens)
- Elongator complex protein 2 (92 kDa, Protein from Homo sapiens)
- Methionine (149 Da, Ligand)
- 5'-deoxyadenosine (251 Da, Ligand)
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8ptz
Q-score: 0.386
Abbassi NE, Jaciuk M, Scherf D, Bohnert P, Rau A, Hammermeister A, Rawski M, Indyka P, Wazny G, Chramiec-Glabik A, Dobosz D, Skupien-Rabian B, Jankowska U, Rappsilber J, Schaffrath R, Lin TY, Glatt S
Nat Commun (2024) 15 pp. 4094-4094 [ DOI: doi:10.1038/s41467-024-48251-y Pubmed: 38750017 ]
- Iron/sulfur cluster (351 Da, Ligand)
- Trna gln (24 kDa, RNA from Homo sapiens)
- Elongator complex protein 2 (92 kDa, Protein from Homo sapiens)
- Elongator complex protein 1 (150 kDa, Protein from Homo sapiens)
- 5'-deoxyadenosine (251 Da, Ligand)
- Elongator complex protein 3 (65 kDa, Protein from Homo sapiens)
- Methionine (149 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Human elp123 in complex with glutamine trna, s-ethyl-coa, 5'-deoxyadenosine and methionine (635 kDa, Complex from Homo sapiens)
- S-ethyl-coa (795 Da, Ligand)
Resolution: 4.25 Å
EM Method: Single-particle
Fitted PDBs: 8pu0
Q-score: 0.277
Abbassi NE, Jaciuk M, Scherf D, Bohnert P, Rau A, Hammermeister A, Rawski M, Indyka P, Wazny G, Chramiec-Glabik A, Dobosz D, Skupien-Rabian B, Jankowska U, Rappsilber J, Schaffrath R, Lin TY, Glatt S
Nat Commun (2024) 15 pp. 4094-4094 [ DOI: doi:10.1038/s41467-024-48251-y Pubmed: 38750017 ]
- 5'-deoxyadenosine (251 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Human elp123 in complex with glutamine trna, desulpho-coa, 5'-deoxyadenosine and methionine (635 kDa, Complex from Homo sapiens)
- Desulfo-coenzyme a (735 Da, Ligand)
- Elongator complex protein 3 (65 kDa, Protein from Homo sapiens)
- Elongator complex protein 1 (150 kDa, Protein from Homo sapiens)
- Elongator complex protein 2 (92 kDa, Protein from Homo sapiens)
- Methionine (149 Da, Ligand)
- Trna gln (24 kDa, RNA from Homo sapiens)