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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"IRON/SULFUR CLUSTER" AND xref_links:"cpx" AND xref_links:"cath"

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EMD-0560

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Structure of the human frataxin-bound iron-sulfur cluster assembly complex

Release date: May 22, 2019
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6nzu
Q-score: 0.546

Fox NG, Yu X, Feng X, Bailey HJ, Martelli A, Nabhan JF, Strain-Damerell C, Bulawa C, Yue WW, Han S

Nat Commun (2019) 10 pp. 2210-2210 [ DOI: doi:10.1038/s41467-019-09989-y Pubmed: 31101807 ]

Sample:

Frataxin, mitochondrial (14 kDa, Protein from Homo sapiens)
Pyridoxal-5'-phosphate (247 Da, Ligand)
Iron-sulfur cluster assembly enzyme iscu, mitochondrial (13 kDa, Protein from Homo sapiens)
Acyl carrier protein (8 kDa, Protein from Escherichia coli)
Lyr motif-containing protein 4 (10 kDa, Protein from Homo sapiens)
Cysteine desulfurase, mitochondrial (44 kDa, Protein from Homo sapiens)
S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
The human frataxin-bound iron-sulfur cluster assembly complex (186 kDa, Complex from Homo sapiens)
Zinc ion (65 Da, Ligand)

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EMD-0452

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Cryo-EM structure of the human TFIIH core complex

Release date: March 13, 2019
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6nmi
Q-score: 0.404

Greber BJ, Toso DB, Fang J, Nogales E

eLife (2019) 8 [ Pubmed: 30860024 DOI: doi:10.7554/eLife.44771 ]

Sample:

General transcription and dna repair factor iih helicase subunit xpd (86 kDa, Protein from Human)
General transcription factor iih subunit 1, p62 (57 kDa, Protein from Human)
General transcription factor iih subunit 5, p8 (8 kDa, Protein from Human)
General transcription and dna repair factor iih helicase subunit xpb (74 kDa, Protein from Human)
General transcription factor iih subunit 4, p52 (52 kDa, Protein from Human)
Iron/sulfur cluster (351 Da, Ligand)
General transcription factor iih subunit 2, p44 (39 kDa, Protein from Human)
General transcription factor iih subunit 3, p34 (34 kDa, Protein from Human)
Zinc ion (65 Da, Ligand)
Cdk-activating kinase assembly factor mat1 (35 kDa, Protein from Human)
Transcription factor iih (tfiih) (500 kDa, Complex from Homo sapiens)

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EMD-4345

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Mouse mitochondrial complex I in the active state

Release date: June 6, 2018
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6g2j
Q-score: 0.469

Agip AA, Blaza JN, Bridges HR, Viscomi C, Rawson S, Muench SP, Hirst J

Nat Struct Mol Biol (2018) 25 pp. 548-556 [ DOI: doi:10.1038/s41594-018-0073-1 Pubmed: 29915388 ]

Sample:

Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mouse)
Flavin mononucleotide (456 Da, Ligand)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mouse)
Adenosine-5'-diphosphate (427 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mouse)
1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mouse)
~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mouse)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mouse)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (7 kDa, Protein from Mouse)
Mitochondrial complex i from mouse in the active state (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mouse)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mouse)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mouse)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mouse)
Iron/sulfur cluster (351 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mouse)
Mcg5603 (15 kDa, Protein from Mouse)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mouse)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mouse)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mouse)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mouse)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mouse)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mouse)

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EMD-4356

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Mouse mitochondrial complex I in the deactive state

Release date: June 6, 2018
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6g72
Q-score: 0.4

Agip AA, Blaza JN, Bridges HR, Viscomi C, Rawson S, Muench SP, Hirst J

Nat Struct Mol Biol (2018) 25 pp. 548-556 [ DOI: doi:10.1038/s41594-018-0073-1 Pubmed: 29915388 ]

Sample:

Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Adenosine-5'-diphosphate (427 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Mcg5603 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Mitochondrial complex i from mouse in the deactive state (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Acetyl group (44 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)

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Sort by: Download

Showing 1 - 4 of 4. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [4]

Format:

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Shell (Unix-based) Batch (Windows-based)

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