Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"IRON/SULFUR CLUSTER" AND xref_links:"cpx" AND xref_links:"cath" AND author_name:"Joseph N" AND xref_links:"uniprot"

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EMD-0560

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Structure of the human frataxin-bound iron-sulfur cluster assembly complex

Release date: May 22, 2019
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6nzu
Q-score: 0.546

Fox NG, Yu X, Feng X, Bailey HJ, Martelli A, Nabhan JF, Strain-Damerell C, Bulawa C, Yue WW, Han S

Nat Commun (2019) 10 pp. 2210-2210 [ DOI: doi:10.1038/s41467-019-09989-y Pubmed: 31101807 ]

Sample:

Frataxin, mitochondrial (14 kDa, Protein from Homo sapiens)
Pyridoxal-5'-phosphate (247 Da, Ligand)
Iron-sulfur cluster assembly enzyme iscu, mitochondrial (13 kDa, Protein from Homo sapiens)
Acyl carrier protein (8 kDa, Protein from Escherichia coli)
Lyr motif-containing protein 4 (10 kDa, Protein from Homo sapiens)
Cysteine desulfurase, mitochondrial (44 kDa, Protein from Homo sapiens)
S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
The human frataxin-bound iron-sulfur cluster assembly complex (186 kDa, Complex from Homo sapiens)
Zinc ion (65 Da, Ligand)

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