Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8esw
Q-score: 0.504
Padavannil A, Murari A, Rhooms SK, Owusu-Ansah E, Letts JA
eLife (2023) 12 [ DOI: doi:10.7554/eLife.84415 Pubmed: 36952377 ]
- Geo11417p1 (10 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (20 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (18 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (46 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (12 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (51 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (17 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (20 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (19 kDa, Protein from fruit fly)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (16 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3 (2 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 4l (11 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 5 (65 kDa, Protein from fruit fly)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from fruit fly)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (16 kDa, Protein from fruit fly)
- Ld31474p (24 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 39 kda subunit, isoform a (46 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from fruit fly)
- Mitochondrial complex i from the thoracic muscles of d. melanogaster (Complex from Drosophila melanogaster)
- 2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (11 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from fruit fly)
- Rh45008p (8 kDa, Protein from fruit fly)
- Zinc ion (65 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (18 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (17 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (14 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 24 kda subunit, isoform a (26 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (78 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 13 kda b subunit (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (14 kDa, Protein from fruit fly)
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (22 kDa, Protein from fruit fly)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from fruit fly)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase (ubiquinone) 23 kda subunit (24 kDa, Protein from fruit fly)
- Flavin mononucleotide (456 Da, Ligand)
- Complex i-49kd (52 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (12 kDa, Protein from fruit fly)
Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8esz
Q-score: 0.498
Padavannil A, Murari A, Rhooms SK, Owusu-Ansah E, Letts JA
eLife (2023) 12 [ DOI: doi:10.7554/eLife.84415 Pubmed: 36952377 ]
- Geo11417p1 (10 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (20 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (18 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (46 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (12 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (51 kDa, Protein from fruit fly)
- Dodecane (170 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (17 kDa, Protein from fruit fly)
- Ubiquinone-10 (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (20 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3 (3 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (19 kDa, Protein from fruit fly)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (16 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 4l (11 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 5 (65 kDa, Protein from fruit fly)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from fruit fly)
- N-octane (114 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (16 kDa, Protein from fruit fly)
- (2r)-3-{[(s)-hydroxy(3-methylbutoxy)phosphoryl]oxy}-2-(octanoyloxy)propyl decanoate (522 Da, Ligand)
- Ld31474p (24 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 39 kda subunit, isoform a (46 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from fruit fly)
- 2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (11 kDa, Protein from fruit fly)
- Rh45008p (8 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from fruit fly)
- Zinc ion (65 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (18 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (17 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (14 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 24 kda subunit, isoform a (26 kDa, Protein from fruit fly)
- Tetradecane (198 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (78 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 13 kda b subunit (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (14 kDa, Protein from fruit fly)
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (22 kDa, Protein from fruit fly)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from fruit fly)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Mitochondrial complex i from the thoracic muscle of drosophila melanogaster (Complex from Drosophila melanogaster)
- Nadh dehydrogenase (ubiquinone) 23 kda subunit (24 kDa, Protein from fruit fly)
- Flavin mononucleotide (456 Da, Ligand)
- Complex i-49kd (52 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (12 kDa, Protein from fruit fly)
Vigna radiata mitochondrial complex I*
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6x89
Q-score: 0.481
Maldonado M, Padavannil A, Zhou L, Guo F, Letts JA
eLife (2020) 9 [ Pubmed: 32840211 DOI: doi:10.7554/eLife.56664 ]
- Nu6m (23 kDa, Protein from Mung bean)
- Uncharacterized protein loc106754061 (6 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial (81 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-a (16 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mung bean)
- Nu1m (35 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (23 kDa, Protein from Mung bean)
- Serine/arginine-rich-splicing factor sr34 isoform x2 (45 kDa, Protein from Mung bean)
- Unknown peptide (2 kDa, Protein from Mung bean)
- Ndua7 (14 kDa, Protein from Mung bean)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mung bean)
- Vigna radiata complex i* (800 kDa, Complex from Vigna radiata)
- Ndus3 (22 kDa, Protein from mung bean)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Gamma carbonic anhydrase 1, mitochondrial-like (29 kDa, Protein from Mung bean)
- Ndus2 (44 kDa, Protein from mung bean)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Gamma carbonic anhydrase 1, mitochondrial (29 kDa, Protein from Mung bean)
- Unknown peptide (1 kDa, Protein from mung bean)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5, mitochondrial (18 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial isoform x1 (43 kDa, Protein from Mung bean)
- Unknown peptide (3 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (25 kDa, Protein from Mung bean)
- Gamma carbonic anhydrase-like 2, mitochondrial (28 kDa, Protein from Mung bean)
- Protein at2g27730, mitochondrial (12 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (7 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (16 kDa, Protein from Mung bean)
- Nu4l (11 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8-b (12 kDa, Protein from Mung bean)
- Nu3m (13 kDa, Protein from Mung bean)
- Nu2m (53 kDa, Protein from Mung bean)
- Ndux1 (10 kDa, Protein from Mung bean)
- Nduc2 (9 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (18 kDa, Protein from Mung bean)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (53 kDa, Protein from Mung bean)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (11 kDa, Protein from Mung bean)