Respiratory complex I from Thermus thermophilus, NADH dataset, major state
Resolution: 4.25 Å
EM Method: Single-particle
Fitted PDBs: 6ziy
Q-score: 0.379
Gutierrez-Fernandez J, Kaszuba K, Minhas GS, Baradaran R, Tambalo M, Gallagher DT, Sazanov LA
Nat Commun (2020) 11 pp. 4135-4135 [ Pubmed: 32811817 DOI: doi:10.1038/s41467-020-17957-0 ]
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh-quinone oxidoreductase subunit 11 (10 kDa, Protein from Thermus thermophilus)
- Respiratory complex i from thermus thermophilus (530 kDa, Complex from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 5 (23 kDa, Protein from Thermus thermophilus)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nadh-quinone oxidoreductase subunit 15 (14 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 10 (18 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 13 (49 kDa, Protein from Thermus thermophilus)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh-quinone oxidoreductase subunit 1 (48 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 12 (65 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 3 (86 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 8 (41 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 2 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 6 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 9 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 7 (13 kDa, Protein from Thermus thermophilus)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-quinone oxidoreductase subunit 14 (44 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 4 (46 kDa, Protein from Thermus thermophilus)
Respiratory complex I from Thermus thermophilus, NAD+ dataset, major state
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6zjl
Q-score: 0.373
Gutierrez-Fernandez J, Kaszuba K, Minhas GS, Baradaran R, Tambalo M, Gallagher DT, Sazanov LA
Nat Commun (2020) 11 pp. 4135-4135 [ Pubmed: 32811817 DOI: doi:10.1038/s41467-020-17957-0 ]
- Nadh-quinone oxidoreductase subunit 6 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 1 (48 kDa, Protein from Thermus thermophilus)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh-quinone oxidoreductase subunit 4 (46 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 3 (86 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 8 (41 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 12 (65 kDa, Protein from Thermus thermophilus)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh-quinone oxidoreductase subunit 14 (44 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 11 (10 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 15 (14 kDa, Protein from Thermus thermophilus)
- Respiratory complex i from thermus thermophilus (530 kDa, Complex from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 10 (18 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 9 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 7 (13 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 13 (49 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 5 (23 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 2 (20 kDa, Protein from Thermus thermophilus)
- Iron/sulfur cluster (351 Da, Ligand)
Respiratory complex I from Thermus thermophilus, NADH dataset, minor state
Resolution: 6.1 Å
EM Method: Single-particle
Fitted PDBs: 6zjn
Q-score: 0.276
Gutierrez-Fernandez J, Kaszuba K, Minhas GS, Baradaran R, Tambalo M, Gallagher DT, Sazanov LA
Nat Commun (2020) 11 pp. 4135-4135 [ Pubmed: 32811817 DOI: doi:10.1038/s41467-020-17957-0 ]
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh-quinone oxidoreductase subunit 15 (14 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 3 (86 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 9 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 12 (65 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 6 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 7 (13 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 8 (41 kDa, Protein from Thermus thermophilus)
- Respiratory complex i from thermus thermophilus (530 kDa, Complex from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 10 (18 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 5 (23 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 11 (10 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 13 (49 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 4 (46 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 14 (44 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 2 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 1 (48 kDa, Protein from Thermus thermophilus)
Respiratory complex I from Thermus thermophilus, NAD+ dataset, minor state
Resolution: 5.5 Å
EM Method: Single-particle
Fitted PDBs: 6zjy
Q-score: 0.289
Gutierrez-Fernandez J, Kaszuba K, Minhas GS, Baradaran R, Tambalo M, Gallagher DT, Sazanov LA
Nat Commun (2020) 11 pp. 4135-4135 [ Pubmed: 32811817 DOI: doi:10.1038/s41467-020-17957-0 ]
- Nadh-quinone oxidoreductase subunit 5 (23 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 1 (48 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 6 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 15 (14 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 10 (18 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 8 (41 kDa, Protein from Thermus thermophilus)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-quinone oxidoreductase subunit 12 (65 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 9 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 7 (13 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 14 (44 kDa, Protein from Thermus thermophilus)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh-quinone oxidoreductase subunit 13 (49 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 11 (10 kDa, Protein from Thermus thermophilus)
- Respiratory complex i from thermus thermophilus (530 kDa, Complex from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 3 (86 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 2 (20 kDa, Protein from Thermus thermophilus)
- Nadh-quinone oxidoreductase subunit 4 (46 kDa, Protein from Thermus thermophilus)