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sample_name:"NADH-ubiquinone oxidoreductase chain 3" AND xref_links:"chebi" AND author_orcid:"0000-0002-9949-6776" AND xref_links:"pdbekb"
Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1
Release date: March 29, 2023
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8esw
Q-score: 0.504
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8esw
Q-score: 0.504
Padavannil A, Murari A, Rhooms SK, Owusu-Ansah E, Letts JA
eLife (2023) 12 [ DOI: doi:10.7554/eLife.84415 Pubmed: 36952377 ]
Sample:
- Geo11417p1 (10 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (20 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (18 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (46 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (12 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (51 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (17 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (20 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (19 kDa, Protein from fruit fly)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (16 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3 (2 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 4l (11 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 5 (65 kDa, Protein from fruit fly)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from fruit fly)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (16 kDa, Protein from fruit fly)
- Ld31474p (24 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 39 kda subunit, isoform a (46 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from fruit fly)
- Mitochondrial complex i from the thoracic muscles of d. melanogaster (Complex from Drosophila melanogaster)
- 2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (11 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from fruit fly)
- Rh45008p (8 kDa, Protein from fruit fly)
- Zinc ion (65 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (18 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (17 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (14 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 24 kda subunit, isoform a (26 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (78 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 13 kda b subunit (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (14 kDa, Protein from fruit fly)
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (22 kDa, Protein from fruit fly)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from fruit fly)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase (ubiquinone) 23 kda subunit (24 kDa, Protein from fruit fly)
- Flavin mononucleotide (456 Da, Ligand)
- Complex i-49kd (52 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (12 kDa, Protein from fruit fly)
Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state
Release date: March 29, 2023
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8esz
Q-score: 0.498
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8esz
Q-score: 0.498
Padavannil A, Murari A, Rhooms SK, Owusu-Ansah E, Letts JA
eLife (2023) 12 [ DOI: doi:10.7554/eLife.84415 Pubmed: 36952377 ]
Sample:
- Geo11417p1 (10 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (20 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (18 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (46 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (12 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (51 kDa, Protein from fruit fly)
- Dodecane (170 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (17 kDa, Protein from fruit fly)
- Ubiquinone-10 (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (20 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3 (3 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (19 kDa, Protein from fruit fly)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (16 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 4l (11 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 5 (65 kDa, Protein from fruit fly)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from fruit fly)
- N-octane (114 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (16 kDa, Protein from fruit fly)
- (2r)-3-{[(s)-hydroxy(3-methylbutoxy)phosphoryl]oxy}-2-(octanoyloxy)propyl decanoate (522 Da, Ligand)
- Ld31474p (24 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 39 kda subunit, isoform a (46 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from fruit fly)
- 2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (11 kDa, Protein from fruit fly)
- Rh45008p (8 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from fruit fly)
- Zinc ion (65 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (18 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (17 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (14 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 24 kda subunit, isoform a (26 kDa, Protein from fruit fly)
- Tetradecane (198 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (78 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from fruit fly)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from fruit fly)
- Nadh dehydrogenase (ubiquinone) 13 kda b subunit (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (14 kDa, Protein from fruit fly)
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (22 kDa, Protein from fruit fly)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from fruit fly)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Mitochondrial complex i from the thoracic muscle of drosophila melanogaster (Complex from Drosophila melanogaster)
- Nadh dehydrogenase (ubiquinone) 23 kda subunit (24 kDa, Protein from fruit fly)
- Flavin mononucleotide (456 Da, Ligand)
- Complex i-49kd (52 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (13 kDa, Protein from fruit fly)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (12 kDa, Protein from fruit fly)
Cryo-EM structure of respiratory super-complex CI+III2 from Tetrahymena thermophila
Release date: April 6, 2022
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7tgh
Q-score: 0.605
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7tgh
Q-score: 0.605
Zhou L, Maldonado M, Padavannil A, Guo F, Letts JA
Science (2022) 376 pp. 831-839 [ Pubmed: 35357889 DOI: doi:10.1126/science.abn7747 ]
Sample:
- Apocytochrome b (50 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (7 kDa, Protein from Tetrahymena thermophila)
- Ymf65 (43 kDa, Protein from Tetrahymena thermophila)
- Zinc-finger protein (15 kDa, Protein from Tetrahymena thermophila)
- Ndutt9 (15 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (29 kDa, Protein from Tetrahymena thermophila)
- Lipid-a-disaccharide synthase (59 kDa, Protein from Tetrahymena thermophila)
- Unk1 (2 kDa, Protein from Tetrahymena thermophila)
- Ymf62 (30 kDa, Protein from Tetrahymena thermophila)
- Ndub10 (22 kDa, Protein from Tetrahymena thermophila)
- Ndub4 (12 kDa, Protein from Tetrahymena thermophila)
- Gamma-carbonic anhydrase (28 kDa, Protein from Tetrahymena thermophila)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Etc complex i subunit motif protein (24 kDa, Protein from Tetrahymena thermophila)
- Uqcrb (39 kDa, Protein from Tetrahymena thermophila)
- Ndub7 (13 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (9 kDa, Protein from Tetrahymena thermophila)
- Peptidase m16 inactive domain protein (58 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (21 kDa, Protein from Tetrahymena thermophila)
- Acyl-coa synthetase (amp-forming)/amp-acid ligase ii (36 kDa, Protein from Tetrahymena thermophila)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 24 kda subunit (31 kDa, Protein from Tetrahymena thermophila)
- Heme c (618 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Transmembrane protein, putative (24 kDa, Protein from Tetrahymena thermophila)
- Thioredoxin (19 kDa, Protein from Tetrahymena thermophila)
- Nadh-ubiquinone oxidoreductase complex i, 21 kda subunit (17 kDa, Protein from Tetrahymena thermophila)
- Unk2 (1 kDa, Protein from Tetrahymena thermophila)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Transmembrane protein, putative (23 kDa, Protein from Tetrahymena thermophila)
- Unk5 (13 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 1 (7 kDa, Protein from Tetrahymena thermophila)
- Rieske iron-sulfur protein, ubiquinol-cytochrome c reductase iron-sulfur subunit (30 kDa, Protein from Tetrahymena thermophila)
- Ndutt3 (35 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (22 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (52 kDa, Protein from Tetrahymena thermophila)
- Nduph2 (22 kDa, Protein from Tetrahymena thermophila)
- Ndutt10 (12 kDa, Protein from Tetrahymena thermophila)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Tetrahymena thermophila)
- Cardiolipin (1 kDa, Ligand)
- Ndutt6 (17 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 10 (18 kDa, Protein from Tetrahymena thermophila)
- Dnaj domain protein (36 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (26 kDa, Protein from Tetrahymena thermophila)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Mitochondrial super-complex i+iii2 of tetrahymena thermophila (2 MDa, Complex from Tetrahymena thermophila)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila)
- Iron/sulfur cluster (351 Da, Ligand)
- Gram domain protein (10 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (14 kDa, Protein from Tetrahymena thermophila)
- Ndua7 (33 kDa, Protein from Tetrahymena thermophila)
- Nadh-ubiquinone oxidoreductase chain 1 (32 kDa, Protein from Tetrahymena thermophila)
- Ndutt12 (11 kDa, Protein from Tetrahymena thermophila)
- Nadh-ubiquinone oxidoreductase 1, chain, putative (28 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase, putative (20 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (58 kDa, Protein from Tetrahymena thermophila)
- Ndub8 (24 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 2 (20 kDa, Protein from Tetrahymena thermophila)
- Ndub6 (15 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 7 (51 kDa, Protein from Tetrahymena thermophila)
- Gamma-carbonic anhydrase (25 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (13 kDa, Protein from Tetrahymena thermophila)
- Ndutt4 (24 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila)
- Flavin mononucleotide (456 Da, Ligand)
- Nduc2 (12 kDa, Protein from Tetrahymena thermophila)
- Ymf57 (12 kDa, Protein from Tetrahymena thermophila)
- Ndua8 (28 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 5 (88 kDa, Protein from Tetrahymena thermophila)
- Ndua13 (21 kDa, Protein from Tetrahymena thermophila)
- Cytochrome protein c1 (37 kDa, Protein from Tetrahymena thermophila)
- Unk3 (1 kDa, Protein from Tetrahymena thermophila)
- Ndutt8 (15 kDa, Protein from Tetrahymena thermophila)
- Ndub9 (22 kDa, Protein from Tetrahymena thermophila)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nad-dependent epimerase/dehydratase family protein (41 kDa, Protein from Tetrahymena thermophila)
- Transcription factor apfi protein, putative (39 kDa, Protein from Tetrahymena thermophila)
- 2 iron, 2 sulfur cluster-binding protein (19 kDa, Protein from Tetrahymena thermophila)
- Unk4 (17 kDa, Protein from Tetrahymena thermophila)
- Ndua1 (11 kDa, Protein from Tetrahymena thermophila)
- Ubiquinol-cytochrome c reductase hinge protein (10 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 9 (23 kDa, Protein from Tetrahymena thermophila)
- M16 family peptidase, putative (53 kDa, Protein from Tetrahymena thermophila)
- Ndub2 (14 kDa, Protein from Tetrahymena thermophila)
- Ubiquinone-10 (863 Da, Ligand)
- Ymf58 (13 kDa, Protein from Tetrahymena thermophila)
- Acyl carrier protein (15 kDa, Protein from Tetrahymena thermophila)
- Ribosomal protein l51/s25/ci-b8 domain protein (12 kDa, Protein from Tetrahymena thermophila)
- Acyl carrier protein (16 kDa, Protein from Tetrahymena thermophila)
- Nadh-ubiquinone oxidoreductase 75 kda subunit (80 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (16 kDa, Protein from Tetrahymena thermophila)