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sample_name:"NADH-ubiquinone oxidoreductase chain 3" AND xref_links:"chebi" AND release_date:[2021-01-01T00:00:00Z TO 2021-12-31T23:59:59Z]
Cryo-EM structure of Arabidopsis thaliana complex-I (closed conformation)
Release date: Dec. 15, 2021
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 7ar8
Q-score: 0.464
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 7ar8
Q-score: 0.464
Klusch N, Senkler J, Yildiz O, Kuehlbrandt W, Braun HP
Plant Cell (2021) 33 pp. 2072-2091 [ Pubmed: 33768254 DOI: doi:10.1093/plcell/koab092 ]
Sample:
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (13 kDa, Protein from Mouse-ear cress)
- P1 (11 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2 (7 kDa, Protein from Mouse-ear cress)
- Gamma carbonic anhydrase 1, mitochondrial (30 kDa, Protein from Mouse-ear cress)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (55 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5-b (9 kDa, Protein from Mouse-ear cress)
- (7s)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide (763 Da, Ligand)
- Probable nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5, mitochondrial (19 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3 (22 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-a (8 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mouse-ear cress)
- B15 -- 1 beta subcomplex subunit 4 (8 kDa, Protein from Mouse-ear cress)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Furry (15 kDa, Protein from Mouse-ear cress)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Cryo-em structure of arabidopsis thaliana complex-i (closed conformation) (Complex from Arabidopsis thaliana)
- 1,2-dicaproyl-sn-phosphatidyl-l-serine (455 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (13 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10-b (12 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial (81 kDa, Protein from Mouse-ear cress)
- At3g07480.1 (17 kDa, Protein from Mouse-ear cress)
- Phosphatidylinositol (887 Da, Ligand)
- Gamma carbonic anhydrase-like 2, mitochondrial (27 kDa, Protein from Mouse-ear cress)
- Probable nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (18 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (7 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mouse-ear cress)
- Zinc ion (65 Da, Ligand)
- Acyl carrier protein 1, mitochondrial (13 kDa, Protein from Mouse-ear cress)
- Acyl carrier protein 2, mitochondrial (14 kDa, Protein from Mouse-ear cress)
- Esss subunit of nadh:ubiquinone oxidoreductase (complex i) protein (12 kDa, Protein from Mouse-ear cress)
- Ubiquinone-9 (795 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (28 kDa, Protein from Mouse-ear cress)
- At2g46540/f11c10.23 (6 kDa, Protein from Mouse-ear cress)
- Transmembrane protein (9 kDa, Protein from Mouse-ear cress)
- At4g16450 (11 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase subunit 4l (11 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (12 kDa, Protein from Mouse-ear cress)
- Gamma carbonic anhydrase 2, mitochondrial (30 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (17 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8-a, mitochondrial (25 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 5 (74 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (53 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 2 (55 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (11 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase subunit 7 (45 kDa, Protein from Mouse-ear cress)
- Fe (iii) ion (55 Da, Ligand)
- Uncharacterized protein at2g27730, mitochondrial (11 kDa, Protein from Mouse-ear cress)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (43 kDa, Protein from Mouse-ear cress)
- Unknown (2 kDa, Protein from Arabidopsis thaliana)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Phosphatidylethanolamine (734 Da, Ligand)
- (1s)-2-{[{[(2r)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (751 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-a (16 kDa, Protein from Mouse-ear cress)
- Excitatory amino acid transporter (9 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 6 (23 kDa, Protein from Mouse-ear cress)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8-b (11 kDa, Protein from Mouse-ear cress)
Cryo-EM structure of Arabidopsis thaliana Complex-I (complete composition)
Release date: Dec. 15, 2021
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 7arb
Q-score: 0.544
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 7arb
Q-score: 0.544
Klusch N, Senkler J, Yildiz O, Kuehlbrandt W, Braun HP
Plant Cell (2021) 33 pp. 2072-2091 [ Pubmed: 33768254 DOI: doi:10.1093/plcell/koab092 ]
Sample:
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (13 kDa, Protein from Mouse-ear cress)
- P1 (11 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2 (7 kDa, Protein from Mouse-ear cress)
- Gamma carbonic anhydrase 1, mitochondrial (30 kDa, Protein from Mouse-ear cress)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (55 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5-b (9 kDa, Protein from Mouse-ear cress)
- (7s)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide (763 Da, Ligand)
- Probable nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5, mitochondrial (19 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3 (22 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-a (8 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mouse-ear cress)
- B15 -- 1 beta subcomplex subunit 4 (8 kDa, Protein from Mouse-ear cress)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Furry (15 kDa, Protein from Mouse-ear cress)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- 1,2-dicaproyl-sn-phosphatidyl-l-serine (455 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (13 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10-b (12 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial (81 kDa, Protein from Mouse-ear cress)
- At3g07480.1 (17 kDa, Protein from Mouse-ear cress)
- Phosphatidylinositol (887 Da, Ligand)
- Gamma carbonic anhydrase-like 2, mitochondrial (27 kDa, Protein from Mouse-ear cress)
- Probable nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (18 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (7 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mouse-ear cress)
- Cryo-em structure of arabidopsis thaliana complex-i (complete composition) (Complex from Arabidopsis thaliana)
- Zinc ion (65 Da, Ligand)
- Acyl carrier protein 1, mitochondrial (13 kDa, Protein from Mouse-ear cress)
- Acyl carrier protein 2, mitochondrial (14 kDa, Protein from Mouse-ear cress)
- Esss subunit of nadh:ubiquinone oxidoreductase (complex i) protein (12 kDa, Protein from Mouse-ear cress)
- Ubiquinone-9 (795 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (28 kDa, Protein from Mouse-ear cress)
- At2g46540/f11c10.23 (6 kDa, Protein from Mouse-ear cress)
- Transmembrane protein (9 kDa, Protein from Mouse-ear cress)
- At4g16450 (11 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase subunit 4l (11 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (12 kDa, Protein from Mouse-ear cress)
- Gamma carbonic anhydrase 2, mitochondrial (30 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (17 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8-a, mitochondrial (25 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 5 (74 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (53 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 2 (55 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (11 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase subunit 7 (45 kDa, Protein from Mouse-ear cress)
- Fe (iii) ion (55 Da, Ligand)
- Uncharacterized protein at2g27730, mitochondrial (11 kDa, Protein from Mouse-ear cress)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (43 kDa, Protein from Mouse-ear cress)
- Unknown (2 kDa, Protein from Arabidopsis thaliana)
- Phosphatidylethanolamine (734 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- (1s)-2-{[{[(2r)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (751 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-a (16 kDa, Protein from Mouse-ear cress)
- Excitatory amino acid transporter (9 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 6 (23 kDa, Protein from Mouse-ear cress)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8-b (11 kDa, Protein from Mouse-ear cress)
Cryo-EM structure of Arabidopsis thaliana Complex-I (membrane core)
Release date: Dec. 8, 2021
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 7aqq
Q-score: 0.549
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 7aqq
Q-score: 0.549
Klusch N, Senkler J, Yildiz O, Kuhlbrandt W, Braun HP
Plant Cell (2021) 33 pp. 2072-2091 [ DOI: doi:10.1093/plcell/koab092 Pubmed: 33768254 ]
Sample:
- Phosphatidylethanolamine (734 Da, Ligand)
- Unknown (2 kDa, Protein from Mouse-ear cress)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Gamma carbonic anhydrase 1, mitochondrial (30 kDa, Protein from Mouse-ear cress)
- Gamma carbonic anhydrase 2, mitochondrial (30 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8-b (11 kDa, Protein from Mouse-ear cress)
- Ubiquinone-9 (795 Da, Ligand)
- Excitatory amino acid transporter (9 kDa, Protein from Mouse-ear cress)
- (1s)-2-{[{[(2r)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (751 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (7 kDa, Protein from Mouse-ear cress)
- P1 (11 kDa, Protein from Mouse-ear cress)
- At3g07480.1 (17 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 5 (74 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 2 (55 kDa, Protein from Mouse-ear cress)
- Arabidopsis complex i - membrane core (Complex from Arabidopsis thaliana)
- Gamma carbonic anhydrase-like 2, mitochondrial (27 kDa, Protein from Mouse-ear cress)
- Nadh-ubiquinone oxidoreductase chain 4 (56 kDa, Protein from Mouse-ear cress)
- At4g16450 (11 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-a (16 kDa, Protein from Mouse-ear cress)
- Fe (iii) ion (55 Da, Ligand)
- Nadh dehydrogenase subunit 4l (11 kDa, Protein from Mouse-ear cress)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5-b (9 kDa, Protein from Mouse-ear cress)
- Zinc ion (65 Da, Ligand)
- Phosphatidylinositol (887 Da, Ligand)
- Uncharacterized protein at2g27730, mitochondrial (11 kDa, Protein from Mouse-ear cress)
- At2g46540/f11c10.23 (6 kDa, Protein from Mouse-ear cress)
- 1,2-dicaproyl-sn-phosphatidyl-l-serine (455 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (23 kDa, Protein from Mouse-ear cress)
- (7s)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide (763 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mouse-ear cress)
Cryo-EM structure of respiratory complex I under turnover
Release date: Nov. 10, 2021
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7o6y
Q-score: 0.468
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7o6y
Q-score: 0.468
Parey K, Lasham J, Mills DJ, Djurabekova A, Haapanen O, Yoga EG, Xie H, Kuhlbrandt W, Sharma V, Vonck J, Zickermann V
Sci Adv (2021) 7 pp. eabj3221-eabj3221 [ DOI: doi:10.1126/sciadv.abj3221 Pubmed: 34767441 ]
Sample:
- Subunit niam of nadh:ubiquinone oxidoreductase (complex i) (17 kDa, Protein from Yarrowia lipolytica)
- Flavin mononucleotide (456 Da, Ligand)
- Subunit nb6m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Cardiolipin (1 kDa, Ligand)
- Subunit nukm of nadh:ubiquinone oxidoreductase (complex i) (23 kDa, Protein from Candida lipolytica)
- Subunit numm of protein nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Candida lipolytica)
- Subunit nujm of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Subunit ni2m of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Candida lipolytica)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Subunit nunm of nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Candida lipolytica)
- Subunit ni9m of protein nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein acpm2 of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Subunit nuvm of nadh:ubiquinone oxidoreductase (complex i) (7 kDa, Protein from Yarrowia lipolytica)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (53 kDa, Protein from Candida lipolytica)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Ubiquinone-9 (795 Da, Ligand)
- Subunit nimm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Candida lipolytica)
- Subunit nb2m of nadh:ubiquinone oxidoreductase (complex i) (6 kDa, Protein from Yarrowia lipolytica)
- Subunit nufm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nesm of nadh:ubiquinone oxidoreductase (complex i) (28 kDa, Protein from Yarrowia lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit nu4m of nadh:ubiquinone oxidoreductase (complex i) (54 kDa, Protein from Yarrowia lipolytica)
- Subunit n7bm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nucm protein (52 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Subunit ni8m of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Candida lipolytica)
- Iron/sulfur cluster (351 Da, Ligand)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- Mitochondrial nadh:ubiquinone oxidoreductase (1 MDa, Complex from Yarrowia lipolytica)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Subunit nuim of nadh:ubiquinone oxidoreductase (complex i) (25 kDa, Protein from Candida lipolytica)
- Acyl carrier protein acpm1 of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Candida lipolytica)
- Subunit nb8m of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Candida lipolytica)
- Subunit nuam of nadh:ubiquinone oxidoreductase (complex i) (79 kDa, Protein from Candida lipolytica)
- Nadh dehydrogenase subunit 2 (53 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from Candida lipolytica)
- Subunit nidm of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Candida lipolytica)
- Subunit nuym of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Candida lipolytica)
- Subunit nuzm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Phosphatidylinositol (887 Da, Ligand)
- Subunit nb5m of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Candida lipolytica)
- Zinc ion (65 Da, Ligand)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Candida lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Subunit nb4m of protein nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Subunit nu5m of nadh:ubiquinone oxidoreductase (complex i) (73 kDa, Protein from Yarrowia lipolytica)
- Subunit nugm of nadh:ubiquinone oxidoreductase (complex i) (32 kDa, Protein from Candida lipolytica)
- Subunit nuem of nadh:ubiquinone oxidoreductase (complex i) (42 kDa, Protein from Yarrowia lipolytica)
- Subunit nuhm of nadh:ubiquinone oxidoreductase (complex i) (27 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 1 (38 kDa, Protein from Yarrowia lipolytica)
- Subunit nuum of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nuxm of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Yarrowia lipolytica)
Cryo-EM structure of a respiratory complex I
Release date: Nov. 10, 2021
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7o71
Q-score: 0.644
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7o71
Q-score: 0.644
Parey K, Lasham J, Mills DJ, Djurabekova A, Haapanen O, Yoga EG, Xie H, Kuhlbrandt W, Sharma V, Vonck J, Zickermann V
Sci Adv (2021) 7 pp. eabj3221-eabj3221 [ DOI: doi:10.1126/sciadv.abj3221 Pubmed: 34767441 ]
Sample:
- Subunit niam of nadh:ubiquinone oxidoreductase (complex i) (17 kDa, Protein from Yarrowia lipolytica)
- Flavin mononucleotide (456 Da, Ligand)
- Subunit nb6m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Cardiolipin (1 kDa, Ligand)
- Subunit nukm of nadh:ubiquinone oxidoreductase (complex i) (23 kDa, Protein from Candida lipolytica)
- Subunit numm of protein nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Candida lipolytica)
- Subunit nujm of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Subunit ni2m of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Candida lipolytica)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Subunit ni9m of protein nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein acpm2 of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Subunit nuvm of nadh:ubiquinone oxidoreductase (complex i) (7 kDa, Protein from Yarrowia lipolytica)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (53 kDa, Protein from Candida lipolytica)
- Subunit nimm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Candida lipolytica)
- Subunit nb2m of nadh:ubiquinone oxidoreductase (complex i) (6 kDa, Protein from Yarrowia lipolytica)
- Subunit nufm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nesm of nadh:ubiquinone oxidoreductase (complex i) (28 kDa, Protein from Yarrowia lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (54 kDa, Protein from Yarrowia lipolytica)
- Subunit n7bm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nucm protein (52 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Subunit ni8m of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Candida lipolytica)
- Iron/sulfur cluster (351 Da, Ligand)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- Mitochondrial nadh:ubiquinone oxidoreductase (1 MDa, Complex from Yarrowia lipolytica)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Subunit nuim of nadh:ubiquinone oxidoreductase (complex i) (25 kDa, Protein from Candida lipolytica)
- Acyl carrier protein acpm1 of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Candida lipolytica)
- Subunit nb8m of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Candida lipolytica)
- Nadh dehydrogenase subunit 2 (53 kDa, Protein from Yarrowia lipolytica)
- Subunit nidm of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from Candida lipolytica)
- Zinc ion (65 Da, Ligand)
- Subunit nuym of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Candida lipolytica)
- Subunit nuzm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Phosphatidylinositol (887 Da, Ligand)
- Subunit nb5m of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Candida lipolytica)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Candida lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase 78 kda subunit (79 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase 40 kda subunit (42 kDa, Protein from Candida lipolytica)
- Subunit nb4m of protein nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Subunit nugm of nadh:ubiquinone oxidoreductase (complex i) (32 kDa, Protein from Candida lipolytica)
- Water (18 Da, Ligand)
- Subunit nuhm of nadh:ubiquinone oxidoreductase (complex i) (27 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 1 (38 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 5 (73 kDa, Protein from Yarrowia lipolytica)
- Subunit nuum of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nuxm of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Candida lipolytica)
- Subunit nunm of nadh:ubiquinone oxidoreductase (complex i) (13 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Yarrowia lipolytica)
Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A
Release date: May 26, 2021
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 7b93
Q-score: 0.565
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 7b93
Q-score: 0.565
Chung I, Serreli R, Cross JB, Di Francesco ME, Marszalek JR, Hirst J
Sci Adv (2021) 7 [ Pubmed: 33990335 DOI: doi:10.1126/sciadv.abg4000 ]
Sample:
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mouse)
- Flavin mononucleotide (456 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mouse)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mouse)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mouse)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Mouse)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mouse)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mouse)
- Respiratory complex i (Complex from Mus musculus)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mouse)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mouse)
- Mcg5603 (15 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mouse)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mouse)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mouse)
- 1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-5-[3-[4-(trifluoromethyloxy)phenyl]-1,2,4-oxadiazol-5-yl]pyridin-2-one (574 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mouse)
A 3.7-angstrom structure of Yarrowia lipolytica complex I with an R121M mutation in NUCM.
Release date: March 10, 2021
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7b0n
Q-score: 0.467
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7b0n
Q-score: 0.467
Hameedi MA, Grba DN, Richardson KH, Jones AJY, Song W, Roessler MM, Wright JJ, Hirst J
J Biol Chem (2021) 296 pp. 100474-100474 [ Pubmed: 33640456 DOI: doi:10.1016/j.jbc.2021.100474 ]
Sample:
- Subunit niam of nadh:ubiquinone oxidoreductase (complex i) (17 kDa, Protein from Yarrowia lipolytica)
- Flavin mononucleotide (456 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Epimerase domain-containing protein (40 kDa, Protein from Yarrowia lipolytica)
- Subunit nidm of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Nucm protein (52 kDa, Protein from Yarrowia lipolytica)
- Subunit nunm of protein nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein (8 kDa, Protein from Yarrowia lipolytica)
- Complex i-b14.7 (18 kDa, Protein from Yarrowia lipolytica)
- Subunit ni9m of protein nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Subunit nuvm of nadh:ubiquinone oxidoreductase (complex i) (7 kDa, Protein from Yarrowia lipolytica)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Subunit nuym of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nuhm of nadh:ubiquinone oxidoreductase (complex i) (27 kDa, Protein from Yarrowia lipolytica)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Grim-19 (13 kDa, Protein from Yarrowia lipolytica)
- Subunit nuam of nadh:ubiquinone oxidoreductase (complex i) (79 kDa, Protein from Yarrowia lipolytica)
- Subunit nufm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nb2m of nadh:ubiquinone oxidoreductase (complex i) (6 kDa, Protein from Yarrowia lipolytica)
- Subunit nesm of nadh:ubiquinone oxidoreductase (complex i) (28 kDa, Protein from Yarrowia lipolytica)
- Zf-chcc domain-containing protein (13 kDa, Protein from Yarrowia lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit nubm of nadh:ubiquinone oxidoreductase (complex i) (53 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 4 (54 kDa, Protein from Yarrowia lipolytica)
- Subunit n7bm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nb5m of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Subunit nb4m of protein nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- Subunit ni2m of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Yarrowia lipolytica)
- Subunit nuxm of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Subunit nb8m of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Subunit nukm of nadh:ubiquinone oxidoreductase (complex i) (23 kDa, Protein from Yarrowia lipolytica)
- Nadh dehydrogenase subunit 2 (53 kDa, Protein from Yarrowia lipolytica)
- Zinc ion (65 Da, Ligand)
- Subunit nuzm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from Yarrowia lipolytica)
- Yarrowia lipolytica mitochondrial complex i (nadh:ubiquinone oxidoreductase) with nucm r121m mutation (Complex from Yarrowia lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Nugm protein (33 kDa, Protein from Yarrowia lipolytica)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (9 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 1 (38 kDa, Protein from Yarrowia lipolytica)
- Subunit nuum of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 5 (73 kDa, Protein from Yarrowia lipolytica)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Subunit nuim of protein nadh:ubiquinone oxidoreductase (complex i) (21 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of protein nadh:ubiquinone oxidoreductase (complex i) [yarrowia lipolytica] (7 kDa, Protein from Yarrowia lipolytica)
- Subunit ni8m of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Yarrowia lipolytica)
Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A
Release date: Feb. 3, 2021
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 7ak5
Q-score: 0.542
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 7ak5
Q-score: 0.542
Yin Z, Burger N, Kula-Alwar D, Aksentijevic D, Bridges HR, Prag HA, Grba DN, Viscomi C, James AM, Mottahedin A, Krieg T, Murphy MP, Hirst J
Nat Commun (2021) 12 pp. 707-707 [ DOI: doi:10.1038/s41467-021-20942-w Pubmed: 33514727 ]
Sample:
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mouse)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mouse)
- Mouse mitochondrial complex i (1 MDa, Complex from Mus musculus)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mouse)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mouse)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mouse)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mouse)
- Flavin mononucleotide (456 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mouse)
- Zinc ion (65 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mouse)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mouse)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (12 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (78 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (7 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mouse)
- Mcg5603 (15 kDa, Protein from Mouse)
Cryo-EM structure of ND6-P25L mutant respiratory complex I from Mus musculus at 3.8 A
Release date: Feb. 3, 2021
Resolution: 3.82 Å
EM Method: Single-particle
Fitted PDBs: 7ak6
Q-score: 0.447
Resolution: 3.82 Å
EM Method: Single-particle
Fitted PDBs: 7ak6
Q-score: 0.447
Yin Z, Burger N, Kula-Alwar D, Aksentijevic D, Bridges HR, Prag HA, Grba DN, Viscomi C, James AM, Mottahedin A, Krieg T, Murphy MP, Hirst J
Nat Commun (2021) 12 pp. 707-707 [ DOI: doi:10.1038/s41467-021-20942-w Pubmed: 33514727 ]
Sample:
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mouse)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Mouse mitochondrial complex i with nd6-p25l mutation (1 MDa, Complex from Mus musculus)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mouse)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (7 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mouse)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mouse)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mouse)
- Mcg5603 (15 kDa, Protein from Mouse)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mouse)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mouse)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mouse)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mouse)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mouse)