Nup93 in complex with 5-Nup93 inhibitory NB and 15-Nup93 tracking NB
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7zox
Q-score: 0.393
Sola Colom M, Fu Z, Gunkel P, Guttler T, Trakhanov S, Srinivasan V, Gregor K, Pleiner T, Gorlich D
EMBO J (2024) [ DOI: doi:10.1038/s44318-024-00081-w Pubmed: 38649536 ]
- Nup93 in complex with 5-nup93 inhibitory nb and 15-nup93 tracking nb (100 kDa, Complex from Xenopus laevis, Vicugna pacos)
- Nuclear pore complex protein nup93 (74 kDa, Protein from Xenopus laevis)
- Xhnup93-nb4i (13 kDa, Protein from Vicugna pacos)
- Xnup93-nb2t (12 kDa, Protein from Vicugna pacos)
Pom34-Pom152 membrane attachment site yeast NPC
Resolution: 7.0 Å
EM Method: Single-particle
Fitted PDBs: 8t9l
Q-score: 0.17
Akey CW, Echeverria I, Ouch C, Nudelman I, Shi Y, Wang J, Chait BT, Sali A, Fernandez-Martinez J, Rout MP
Mol Cell (2023) 83 pp. 3283-3302.e5 [ Pubmed: 37738963 DOI: doi:10.1016/j.molcel.2023.08.025 ]
- Nuclear pore complex (Complex from Saccharomyces cerevisiae)
- Nucleoporin pom34 (34 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin pom152 (151 kDa, Protein from Saccharomyces cerevisiae)
- Pom34-pom152 inner ring anchor complex (Complex from Saccharomyces cerevisiae)
Double nuclear outer ring of Nup84-complexes from the yeast NPC
Resolution: 8.1 Å
EM Method: Single-particle
Fitted PDBs: 8tie
Q-score: 0.08
Akey CW, Echeverria I, Ouch C, Nudelman I, Shi Y, Wang J, Chait BT, Sali A, Fernandez-Martinez J, Rout MP
Mol Cell (2023) 83 pp. 3283-3302.e5 [ Pubmed: 37738963 DOI: doi:10.1016/j.molcel.2023.08.025 ]
- Nup145 isoform 1 (145 kDa, Protein from Saccharomyces cerevisiae)
- Protein transport protein sec13 (33 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup120 (120 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup85 (84 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup84 (83 kDa, Protein from Saccharomyces cerevisiae)
- Double nup84 y-complex (Complex from Saccharomyces cerevisiae)
- Nuclear pore complex (Complex from Saccharomyces cerevisiae)
- Nup133 isoform 1 (133 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin seh1 (34 kDa, Protein from Saccharomyces cerevisiae)
Inner spoke ring of the yeast NPC
Resolution: 6.6 Å
EM Method: Single-particle
Fitted PDBs: 8tj5
Q-score: 0.113
Akey CW, Echeverria I, Ouch C, Nudelman I, Shi Y, Wang J, Chait BT, Sali A, Fernandez-Martinez J, Rout MP
Mol Cell (2023) 83 pp. 3283-3302.e5 [ Pubmed: 37738963 DOI: doi:10.1016/j.molcel.2023.08.025 ]
- Nuclear pore complex (18 MDa, Complex from Saccharomyces cerevisiae)
- Nucleoporin nup57 (57 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup192 (191 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup188 (188 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup53 (52 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nsp1 (86 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup170 (169 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nic96 (96 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup157 (156 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin 59 (58 kDa, Protein from Saccharomyces cerevisiae)
- Nucleoporin nup49/nsp49 (49 kDa, Protein from Saccharomyces cerevisiae)
- Spoke connector (3 kDa, Protein from Saccharomyces cerevisiae)
The cryo-EM map of the core region from the X. laevis NPC CR subunit
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7fik
Q-score: 0.346
Zhu X, Huang G, Zeng C, Zhan X, Liang K, Xu Q, Zhao Y, Wang P, Wang Q, Zhou Q, Tao Q, Liu M, Lei J, Yan C, Shi Y
Science (2022) 376 pp. eabl8280-eabl8280 [ Pubmed: 35679404 DOI: doi:10.1126/science.abl8280 ]
- Nucleoporin seh1-b (39 kDa, Protein from Xenopus laevis)
- Mgc83295 protein (227 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup85 (75 kDa, Protein from Xenopus laevis)
- Outer nup160 (162 kDa, Protein from Xenopus laevis)
- Mgc154553 protein (41 kDa, Protein from Xenopus laevis)
- Outer nup133 (127 kDa, Protein from Xenopus laevis)
- Mgc83926 protein (36 kDa, Protein from Xenopus laevis)
- Nup155-prov protein (154 kDa, Protein from Xenopus laevis)
- Xenopus laevis nuclear pore complex (npc) (Complex from Xenopus laevis)
- Nuclear pore complex protein nup93 (93 kDa, Protein from Xenopus laevis)
- Nucleoporin nup88a (82 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup133 (111 kDa, Protein from Xenopus laevis)
- Nup98 (13 kDa, Protein from Xenopus laevis)
- Nup358 complex, clamps (322 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein nup98-nup96 (191 kDa, Protein from Xenopus laevis)
- Nuclear pore complex protein (105 kDa, Protein from Xenopus laevis)
- Protein sec13 homolog (35 kDa, Protein from Xenopus laevis)
Human nuclear pore complex (dilated)
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
- Aladin (59 kDa, Protein from human)
- Nucleoporin p58/p45 (60 kDa, Protein from human)
- Nuclear pore complex protein nup133 (129 kDa, Protein from human)
- Nucleoporin nup188 homolog (196 kDa, Protein from human)
- Protein sec13 homolog (35 kDa, Protein from human)
- Nucleoporin nup43 (42 kDa, Protein from human)
- Nuclear pore complex protein nup160 (162 kDa, Protein from human)
- Human nuclear pore complex from hek cells (Cellular component from Homo sapiens)
- Nucleoporin nup37 (36 kDa, Protein from human)
- Nucleoporin nup35 (34 kDa, Protein from human)
- Nuclear pore complex protein nup205 (228 kDa, Protein from human)
- Nuclear pore complex protein nup98 (91 kDa, Protein from human)
- E3 sumo-protein ligase ranbp2 (358 kDa, Protein from human)
- Nuclear pore complex protein nup93 (93 kDa, Protein from human)
- Protein elys (252 kDa, Protein from human)
- Nuclear pore membrane glycoprotein 210 (205 kDa, Protein from human)
- Nucleoporin ndc1 (76 kDa, Protein from human)
- Nuclear pore complex protein nup155 (155 kDa, Protein from human)
- Nuclear pore complex protein nup214 (213 kDa, Protein from human)
- Nuclear pore complex protein nup96 (106 kDa, Protein from human)
- Nucleoporin seh1 (39 kDa, Protein from human)
- Nuclear pore complex protein nup107 (106 kDa, Protein from human)
- Nuclear pore complex protein nup88 (83 kDa, Protein from human)
- Nuclear pore complex protein nup85 (75 kDa, Protein from human)
- Nucleoporin p54 (55 kDa, Protein from human)
- Nuclear pore glycoprotein p62 (53 kDa, Protein from human)
Human nuclear pore complex (constricted)
Resolution: 12.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7r5k
Q-score: 0.034
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
- Aladin (59 kDa, Protein from human)
- Nuclear pore complex (120 MDa, Cellular component from Homo sapiens)
- Nucleoporin p58/p45 (60 kDa, Protein from human)
- Nuclear pore complex protein nup133 (129 kDa, Protein from human)
- Nucleoporin nup188 homolog (196 kDa, Protein from human)
- Protein sec13 homolog (35 kDa, Protein from human)
- Nucleoporin nup43 (42 kDa, Protein from human)
- Nuclear pore complex protein nup160 (162 kDa, Protein from human)
- Nucleoporin nup37 (36 kDa, Protein from human)
- Nucleoporin nup35 (34 kDa, Protein from human)
- Nuclear pore complex protein nup205 (228 kDa, Protein from human)
- Nuclear pore complex protein nup98 (91 kDa, Protein from human)
- E3 sumo-protein ligase ranbp2 (358 kDa, Protein from human)
- Nuclear pore complex protein nup93 (93 kDa, Protein from human)
- Protein elys (252 kDa, Protein from human)
- Nuclear pore membrane glycoprotein 210 (205 kDa, Protein from human)
- Nucleoporin ndc1 (76 kDa, Protein from human)
- Nuclear pore complex protein nup155 (155 kDa, Protein from human)
- Nuclear pore complex protein nup214 (213 kDa, Protein from human)
- Nuclear pore complex protein nup96 (106 kDa, Protein from human)
- Nucleoporin seh1 (39 kDa, Protein from human)
- Nuclear pore complex protein nup107 (106 kDa, Protein from human)
- Nuclear pore complex protein nup88 (83 kDa, Protein from human)
- Nuclear pore complex protein nup85 (75 kDa, Protein from human)
- Nucleoporin p54 (55 kDa, Protein from human)
- Nuclear pore glycoprotein p62 (53 kDa, Protein from human)
cryoEM structure of human Nup155 (residues 19-981)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7r1y
Q-score: 0.48
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
- Nup155 from homo sapiens (Cellular component from Homo sapiens)
- Nuclear pore complex protein nup155 (154 kDa, Protein from Homo sapiens)
Cryo-EM (SPA) structure of Nup155 N-terminus (19-863) at 5.1 Angstrom resolution
Resolution: 5.1 Å
EM Method: Single-particle
Fitted PDBs: 7eye
Q-score: 0.21
To Be Published
Cryo-EM (SPA) structure of human Nup155 C-terminus (864-1337) at 5.3 Angstroms resolution
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 7eyf
Q-score: 0.191
To Be Published
- Nuclear pore complex protein nup155 (60 kDa, Protein from Homo sapiens)
- Purified nup155 protein (58 MDa, Cellular component from Homo sapiens)