Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B.
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8b7y
Q-score: 0.556
Koller TO, Scheid U, Kosel T, Herrmann J, Krug D, Boshoff HIM, Beckert B, Evans JC, Schlemmer J, Sloan B, Weiner DM, Via LE, Moosa A, Ioerger TR, Graf M, Zinshteyn B, Abdelshahid M, Nguyen F, Arenz S, Gille F, Siebke M, Seedorf T, Plettenburg O, Green R, Warnke AL, Ullrich J, Warrass R, Barry 3rd CE, Warner DF, Mizrahi V, Kirschning A, Wilson DN, Muller R
J Am Chem Soc (2023) 145 pp. 851-863 [ DOI: doi:10.1021/jacs.2c08816 Pubmed: 36603206 ]
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s19 (10 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli K-12)
- 16s ribosomal rna (496 kDa, RNA from Escherichia coli K-12)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli K-12)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli K-12)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli K-12)
- N-formylmethionine (177 Da, Ligand)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli K-12)
- Cryo-em structure of the e.coli 70s ribosome in complex with the antibiotic myxovalargin b. (2 MDa, Complex from Escherichia coli BW25113)
- 30s ribosomal protein s3 (26 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli K-12)
- P-trna fmet (24 kDa, RNA from Escherichia coli K-12)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s6 (15 kDa, Protein from Escherichia coli K-12)
- Myxovalargin b (1 kDa, Protein from Myxococcus fulvus)
- Zinc ion (65 Da, Ligand)
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s11 (13 kDa, Protein from Escherichia coli K-12)
- Spermidine (145 Da, Ligand)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli K-12)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli K-12)
- 30s ribosomal protein s2 (26 kDa, Protein from Escherichia coli K-12)
- Water (18 Da, Ligand)
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli K-12)
- Magnesium ion (24 Da, Ligand)
- 30s ribosomal protein s18 (9 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s5 (17 kDa, Protein from Escherichia coli K-12)
- Messenger rna (935 Da, RNA from Escherichia coli K-12)
- 30s ribosomal protein s21 (8 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s13 (13 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli K-12)
Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7nsp
Q-score: 0.448
Beckert B, Leroy EC, Sothiselvam S, Bock LV, Svetlov MS, Graf M, Arenz S, Abdelshahid M, Seip B, Grubmuller H, Mankin AS, Innis CA, Vazquez-Laslop N, Wilson DN
Nat Commun (2021) 12 pp. 4466-4466 [ DOI: doi:10.1038/s41467-021-24674-9 Pubmed: 34294725 ]
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s3 (23 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- P-trna (leu) (28 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l17 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s7 (16 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- Ermdl (877 Da, Protein from Escherichia coli)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 16s rrna (499 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s19 (9 kDa, Protein from Escherichia coli)
- A-trna (arg) (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- Erythromycin a (733 Da, Ligand)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s21 (8 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (5 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s6 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s18 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (8 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s2 (24 kDa, Protein from Escherichia coli)
- Structure of ermdl-erythromycin-stalled 70s e. coli ribosomal complex with a and p-trna (Complex from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli)
- Mrna (1 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s13 (12 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s11 (12 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l28 (8 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s5 (16 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with P-tRNA
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7nso
Q-score: 0.551
Beckert B, Leroy EC, Sothiselvam S, Bock LV, Svetlov MS, Graf M, Arenz S, Abdelshahid M, Seip B, Grubmuller H, Mankin AS, Innis CA, Vazquez-Laslop N, Wilson DN
Nat Commun (2021) 12 pp. 4466-4466 [ DOI: doi:10.1038/s41467-021-24674-9 Pubmed: 34294725 ]
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s3 (23 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- Structure of ermdl-erythromycin-stalled 70s e. coli ribosomal complex with p-trna (Complex from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s7 (16 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- Ermdl (877 Da, Protein from Escherichia coli)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- Ptrna-leu (28 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s19 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 16s rrna (1540-mer) (499 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- Erythromycin a (733 Da, Ligand)
- 30s ribosomal protein s21 (8 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (5 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s6 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s18 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (8 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli)
- 23s rrna (2903-mer) (941 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s2 (24 kDa, Protein from Escherichia coli)
- Mrna (872 Da, RNA from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s13 (12 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s11 (12 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l28 (8 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s5 (16 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
Structure of ErmDL-Telithromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7nsq
Q-score: 0.52
Beckert B, Leroy EC, Sothiselvam S, Bock LV, Svetlov MS, Graf M, Arenz S, Abdelshahid M, Seip B, Grubmuller H, Mankin AS, Innis CA, Vazquez-Laslop N, Wilson DN
Nat Commun (2021) 12 pp. 4466-4466 [ DOI: doi:10.1038/s41467-021-24674-9 Pubmed: 34294725 ]
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli)
- Telithromycin (812 Da, Ligand)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s3 (23 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- Structure of ermdl-erythromycin-stalled 70s e. coli ribosomal complex with p-trna (Complex from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s7 (16 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- Ermdl (877 Da, Protein from Escherichia coli)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 16s rrna (499 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s19 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s21 (8 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (5 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s6 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s18 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (8 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli)
- Ptrna (leu) (28 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s2 (24 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli)
- Mrna (1 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s13 (12 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s11 (12 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l28 (8 kDa, Protein from Escherichia coli)
- Atrna (arg) (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s5 (16 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6ha1
Q-score: 0.48
Crowe-McAuliffe C, Graf M, Huter P, Takada H, Abdelshahid M, Novacek J, Murina V, Atkinson GC, Hauryliuk V, Wilson DN
PNAS (2018) 115 pp. 8978-8983 [ Pubmed: 30126986 DOI: doi:10.1073/pnas.1808535115 ]
- 30s ribosomal protein s17 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s11 (13 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l27 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s9 (14 kDa, Protein from Bacillus subtilis (strain 168))
- Telithromycin (812 Da, Ligand)
- 50s ribosomal protein l6 (19 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s10 (11 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l31 (7 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l28 (6 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s14 (7 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s2 (28 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l33 1 (5 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s18 (8 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l24 (11 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s7 (17 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l15 (15 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l32 (6 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s6 (11 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l36 (4 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s19 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s15 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l4 (22 kDa, Protein from Bacillus subtilis (strain 168))
- 70s ribosome (Complex from Bacillus subtilis (strain 168))
- 30s ribosomal protein s13 (13 kDa, Protein from Bacillus subtilis (strain 168))
- 23s ribosomal rna (949 kDa, RNA from Bacillus subtilis (strain 168))
- 50s ribosomal protein l22 (12 kDa, Protein from Bacillus subtilis (strain 168))
- 16s ribosomal rna (503 kDa, RNA from Bacillus subtilis (strain 168))
- 50s ribosomal protein l14 (13 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l17 (13 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l23 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l19 (13 kDa, Protein from Bacillus subtilis (strain 168))
- Mrna (872 Da, RNA from Bacillus subtilis (strain 168))
- 50s ribosomal protein l5 (20 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l35 (7 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l30 (6 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s16 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 70s ribosome with p-trna translating the ermd stalling peptide and complexed with telithromycin (Complex)
- 50s ribosomal protein l20 (13 kDa, Protein from Bacillus subtilis (strain 168))
- Trna (Complex from Escherichia coli)
- 30s ribosomal protein s3 (24 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s8 (14 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l13 (16 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l21 (11 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l34 (5 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s4 (22 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l16 (16 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l29 (7 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s12 (15 kDa, Protein from Bacillus subtilis (strain 168))
- Ermd stalling peptide (Complex from Bacillus subtilis (strain 168))
- 50s ribosomal protein l3 (22 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s5 (17 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l2 (30 kDa, Protein from Bacillus subtilis (strain 168))
- 5s ribosomal rna (36 kDa, RNA from Bacillus subtilis (strain 168))
- 30s ribosomal protein s20 (9 kDa, Protein from Bacillus subtilis (strain 168))
- P-trna (28 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Bacillus subtilis (strain 168))
Cryo-EM structure of the ABCF protein VmlR bound to the Bacillus subtilis ribosome
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6ha8
Q-score: 0.389
Crowe-McAuliffe C, Graf M, Huter P, Takada H, Abdelshahid M, Novacek J, Murina V, Atkinson GC, Hauryliuk V, Wilson DN
PNAS (2018) 115 pp. 8978-8983 [ Pubmed: 30126986 DOI: doi:10.1073/pnas.1808535115 ]
- 30s ribosomal protein s17 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s11 (13 kDa, Protein from Bacillus subtilis (strain 168))
- 5s rrna (36 kDa, RNA from Bacillus subtilis (strain 168))
- 50s ribosomal protein l27 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s9 (14 kDa, Protein from Bacillus subtilis (strain 168))
- Telithromycin (812 Da, Ligand)
- Complex of translating 70s ribosome with abcf antibiotic resistance protein vmlr (Complex)
- 50s ribosomal protein l6 (19 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s10 (11 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l1 (25 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l28 (6 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s14 (7 kDa, Protein from Bacillus subtilis (strain 168))
- 23s rrna (949 kDa, RNA from Bacillus subtilis (strain 168))
- 30s ribosomal protein s2 (28 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l33 1 (5 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s18 (8 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l24 (11 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s7 (17 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l15 (15 kDa, Protein from Bacillus subtilis (strain 168))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 50s ribosomal protein l32 (6 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l36 (4 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s19 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s15 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l4 (22 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s13 (13 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l22 (12 kDa, Protein from Bacillus subtilis (strain 168))
- Nucleotide-binding protein expz (Complex from Bacillus subtilis subsp. subtilis str. 168)
- 50s ribosomal protein l31 (7 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l14 (13 kDa, Protein from Bacillus subtilis (strain 168))
- Mrna (872 Da, RNA from Bacillus subtilis subsp. subtilis str. 168)
- 50s ribosomal protein l17 (13 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l23 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l19 (13 kDa, Protein from Bacillus subtilis (strain 168))
- Ribosome (Complex from Bacillus subtilis subsp. subtilis str. 168)
- 50s ribosomal protein l5 (20 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l35 (7 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l30 (6 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s16 (10 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l20 (13 kDa, Protein from Bacillus subtilis (strain 168))
- Trna (Complex from Escherichia coli)
- 30s ribosomal protein s3 (24 kDa, Protein from Bacillus subtilis (strain 168))
- Nucleotide-binding protein expz (60 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l13 (16 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l21 (11 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l34 (5 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s4 (22 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l16 (16 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l29 (7 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s8 (14 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s12 (15 kDa, Protein from Bacillus subtilis (strain 168))
- P-trna(leu) (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s5 (17 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l2 (30 kDa, Protein from Bacillus subtilis (strain 168))
- 16s rrna (503 kDa, RNA from Bacillus subtilis (strain 168))
- 30s ribosomal protein s6 (11 kDa, Protein from Bacillus subtilis (strain 168))
- 30s ribosomal protein s20 (9 kDa, Protein from Bacillus subtilis (strain 168))
- 50s ribosomal protein l18 (12 kDa, Protein from Bacillus subtilis (strain 168))