PfRH5-PfCyRPA-PfRIPR complex from Plasmodium falciparum bound to antibody Cy.003
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8cdd
Q-score: 0.425
Farrell B, Alam N, Hart MN, Jamwal A, Ragotte RJ, Walters-Morgan H, Draper SJ, Knuepfer E, Higgins MK
Nature (2024) 625 pp. 578-584 [ DOI: doi:10.1038/s41586-023-06856-1 Pubmed: 38123677 ]
- Cy.003 light chain (22 kDa, Protein from Gallus gallus)
- Cysteine-rich protective antigen (40 kDa, Protein from Plasmodium falciparum 3D7)
- Cy.003 heavy chain (23 kDa, Protein from Gallus gallus)
- Rh5-interacting protein (124 kDa, Protein from Plasmodium falciparum 3D7)
- Reticulocyte-binding protein homolog 5 (60 kDa, Protein from Plasmodium falciparum 3D7)
- Pfrh5-pfcyrpa-pfripr complex bound to fab fragment from antibody cy.003 (Complex from Plasmodium falciparum 3D7)
PfCyRPA-PfRIPR complex from Plasmodium falciparum bound to antibody Cy.003
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8cde
Q-score: 0.409
Farrell B, Alam N, Hart MN, Jamwal A, Ragotte RJ, Walters-Morgan H, Draper SJ, Knuepfer E, Higgins MK
Nature (2024) 625 pp. 578-584 [ DOI: doi:10.1038/s41586-023-06856-1 Pubmed: 38123677 ]
- Rh5-interacting protein (124 kDa, Protein from Plasmodium falciparum 3D7)
- Cy.003 light chain (22 kDa, Protein from Gallus gallus)
- Cy.003 (23 kDa, Protein from Gallus gallus)
- Pfcyrpa-pfripr complex bound to fab fragment from antibody cy.003 (Complex from Plasmodium falciparum 3D7)
- Cysteine-rich protective antigen (40 kDa, Protein from Plasmodium falciparum 3D7)
Farrell B, Alam N, Hart MN, Jamwal A, Ragotte RJ, Walters-Morgan H, Draper SJ, Knuepfer E, Higgins MK
Nature (2024) 625 pp. 578-584 [ DOI: doi:10.1038/s41586-023-06856-1 Pubmed: 38123677 ]
PfCyRPA-PfRIPR complex from Plasmodium falciparum bound to antibody Cy.003 consensus maps
Farrell B, Alam N, Hart MN, Jamwal A, Ragotte RJ, Walters-Morgan H, Draper SJ, Knuepfer E, Higgins MK
Nature (2024) 625 pp. 578-584 [ DOI: doi:10.1038/s41586-023-06856-1 Pubmed: 38123677 ]
PfRH5-PfCyRPA-PfRIPR complex from Plasmodium falciparum bound to antibody Cy.003 - consensus map
Farrell B, Alam N, Hart MN, Jamwal A, Ragotte RJ, Walters-Morgan H, Draper SJ, Knuepfer E, Higgins MK
Nature (2024) 625 pp. 578-584 [ DOI: doi:10.1038/s41586-023-06856-1 Pubmed: 38123677 ]
Farrell B, Alam N, Hart MN, Jamwal A, Ragotte RJ, Walters-Morgan H, Draper SJ, Knuepfer E, Higgins MK
Nature (2024) 625 pp. 578-584 [ DOI: doi:10.1038/s41586-023-06856-1 Pubmed: 38123677 ]
Farrell B, Alam N, Hart MN, Jamwal A, Ragotte RJ, Walters-Morgan H, Draper SJ, Knuepfer E, Higgins MK
Nature (2024) 625 pp. 578-584 [ DOI: doi:10.1038/s41586-023-06856-1 Pubmed: 38123677 ]
Farrell B, Alam N, Hart MN, Jamwal A, Ragotte RJ, Walters-Morgan H, Draper SJ, Knuepfer E, Higgins MK
Nature (2024) 625 pp. 578-584 [ DOI: doi:10.1038/s41586-023-06856-1 Pubmed: 38123677 ]
Structure of Plasmodium falciparum CyRPA/Ripr invasion complex
Nature (2018) [ ]
- Cyrpr/pfripr complex (163 MDa, Complex from Plasmodium falciparum 3D7)
Cryo-electron microscopy structure of Plasmodium falciparum Rh5/CyRPA/Ripr invasion complex
Resolution: 7.17 Å
EM Method: Single-particle
Fitted PDBs: 6mpv
Q-score: 0.191
Wong W, Huang R, Menant S, Hong C, Sandow JJ, Birkinshaw RW, Healer J, Hodder AN, Kanjee U, Tonkin CJ, Heckmann D, Soroka V, Sogaard TMM, Jorgensen T, Duraisingh MT, Czabotar PE, de Jongh WA, Tham WH, Webb AI, Yu Z, Cowman AF
Nature (2019) 565 pp. 118-121 [ DOI: doi:10.1038/s41586-018-0779-6 Pubmed: 30542156 ]
- Pfripr (1 kDa, Protein from Plasmodium falciparum 3D7)
- Pfripr (443 Da, Protein from Plasmodium falciparum 3D7)
- Pfrh5/cyrpa/pfripr complex (Complex from Plasmodium falciparum 3D7)
- Cysteine-rich protective antigen (39 kDa, Protein from Plasmodium falciparum (isolate 3D7))
- Reticulocyte binding protein 5 (39 kDa, Protein from Plasmodium falciparum)