Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"Prefusion SARS-CoV-2 spike glycoprotein in complex with 1-57 Fab"

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EMD-23506

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Cryo-EM structure of neutralizing antibody 1-57 in complex with prefusion SARS-CoV-2 spike glycoprotein

Release date: March 17, 2021
Resolution: 3.42 Å
EM Method: Single-particle
Fitted PDBs: 7ls9
Q-score: 0.429

Cerutti G, Rapp M, Guo Y, Bahna F, Bimela J, Reddem ER, Yu J, Wang P, Liu L, Huang Y, Ho DD, Kwong PD, Sheng Z, Shapiro L

Structure (2021) 29 pp. 655-663.e4 [ DOI: doi:10.1016/j.str.2021.05.014 Pubmed: 34111408 ]

Sample:

2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
1-57 fab heavy chain (26 kDa, Protein from Homo sapiens)
1-57 fab light chain (23 kDa, Protein from Homo sapiens)
Prefusion sars-cov-2 spike glycoprotein in complex with 1-57 fab (Complex from Severe acute respiratory syndrome coronavirus 2)

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