Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"RNA (5'-R(*CP*UP*AP*UP*UP*AP*AP*AP*AP*UP*CP*AP*CP*C)-3')"

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EMD-24104

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Cryo-EM structure of the tetrameric form of SARS-CoV-2 nsp10-nsp14 (E191A)-RNA complex

Release date: July 28, 2021
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7n0d
Q-score: 0.542

Liu C, Shi W, Becker ST, Schatz DG, Liu B, Yang Y

Science (2021) 373 pp. 1142-1146 [ Pubmed: 34315827 DOI: doi:10.1126/science.abi9310 ]

Sample:

Proofreading exoribonuclease (59 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Rna (5'-r(*gp*gp*gp*gp*ap*up*gp*up*gp*ap*up*up*up*up*ap*ap*up*ap*g)-3') (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
Rna (5'-r(*cp*cp*cp*cp*c)-3') (1 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
Chapso (631 Da, Ligand)
Water (18 Da, Ligand)
Non-structural protein 10 (14 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Tetrameric form of sars-cov-2 nsp10-nsp14 (e191a)-rna complex (Complex from Severe acute respiratory syndrome coronavirus 2)
Magnesium ion (24 Da, Ligand)
Zinc ion (65 Da, Ligand)
Rna (5'-r(*cp*up*ap*up*up*ap*ap*ap*ap*up*cp*ap*cp*c)-3') (7 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)

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