Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-His(5,Ser)
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8cbk
Q-score: 0.452
Meynier V, Hardwick SW, Catala M, Roske JJ, Oerum S, Chirgadze DY, Barraud P, Yue WW, Luisi BF, Tisne C
Nat Commun (2024) 15 pp. 4683-4683 [ DOI: doi:10.1038/s41467-024-49132-0 Pubmed: 38824131 ]
- Human mitochondrial rnase p in complex with mitochondrial pre-trnahis-ser (269 kDa, Complex from Homo sapiens)
- Mitochondrial precursor trna-his(5,ser) (29 kDa, RNA from Homo sapiens)
- Trna methyltransferase 10 homolog c (48 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 3-hydroxyacyl-coa dehydrogenase type-2 (26 kDa, Protein from Homo sapiens)
- Mitochondrial ribonuclease p catalytic subunit (61 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
Structure of human mitochondrial RNase Z in complex with mitochondrial pre-tRNA-His(0,Ser)
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 8cbl
Q-score: 0.443
Meynier V, Hardwick SW, Catala M, Roske JJ, Oerum S, Chirgadze DY, Barraud P, Yue WW, Luisi BF, Tisne C
Nat Commun (2024) 15 pp. 4683-4683 [ DOI: doi:10.1038/s41467-024-49132-0 Pubmed: 38824131 ]
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
- Zinc phosphodiesterase elac protein 2 (92 kDa, Protein from Homo sapiens)
- Trna methyltransferase 10 homolog c (48 kDa, Protein from Homo sapiens)
- 3-hydroxyacyl-coa dehydrogenase type-2 (26 kDa, Protein from Homo sapiens)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Human mitochondrial rnase p in complex with mitochondrial pre-trna-his(0,ser) (300 kDa, Complex from Homo sapiens)
- Mitochondrial precursor trna-his(0,ser) (40 kDa, RNA from Homo sapiens)
E.coli RNaseP Holoenzyme with Mg2+
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7uo0
Q-score: 0.148
Zhu J, Huang W, Zhao J, Huynh L, Taylor DJ, Harris ME
Nat Commun (2022) 13 pp. 5120-5120 [ Pubmed: 36045135 DOI: doi:10.1038/s41467-022-32843-7 ]
- Precursor trna substrate g(-1) g(-2) (26 kDa, RNA from Escherichia coli)
- Ribonuclease p protein component (13 kDa, Protein from Escherichia coli)
- E.coli rnase p holoenzyme with mg2+ (Complex from Escherichia coli)
- Rnase p rna (121 kDa, RNA from Escherichia coli)
- Calcium ion (40 Da, Ligand)
E.coli RNaseP Holoenzyme with Mg2+
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7uo1
Q-score: 0.289
Zhu J, Huang W, Zhao J, Huynh L, Taylor DJ, Harris ME
Nat Commun (2022) 13 pp. 5120-5120 [ Pubmed: 36045135 DOI: doi:10.1038/s41467-022-32843-7 ]
- E.coli rnase p holoenzyme with pre-trna substrate au (Complex from Escherichia coli)
- Ribonuclease p protein component (13 kDa, Protein from Escherichia coli)
- E.coli rnase p rna (121 kDa, RNA from Escherichia coli)
- Precursor trna substrate u(-1) and a(-2) (26 kDa, RNA from Escherichia coli)
- Calcium ion (40 Da, Ligand)
E.coli RNaseP Holoenzyme with Mg2+
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uo2
Q-score: 0.345
Zhu J, Huang W, Zhao J, Huynh L, Taylor DJ, Harris ME
Nat Commun (2022) 13 pp. 5120-5120 [ Pubmed: 36045135 DOI: doi:10.1038/s41467-022-32843-7 ]
- Rnase p rna (122 kDa, RNA from Escherichia coli)
- Ribonuclease p protein component (13 kDa, Protein from Escherichia coli)
- E.coli rnase p holoenzyme with mg2+ (Complex from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
E.coli RNaseP Holoenzyme with Mg2+
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uo5
Q-score: 0.365
Zhu J, Huang W, Zhao J, Huynh L, Taylor DJ, Harris ME
Nat Commun (2022) 13 pp. 5120-5120 [ Pubmed: 36045135 DOI: doi:10.1038/s41467-022-32843-7 ]
- Ribonuclease p protein component (13 kDa, Protein from Escherichia coli)
- Rnase p rna (121 kDa, RNA from Escherichia coli)
- Calcium ion (40 Da, Ligand)
- E.coli rnase p holoenzyme with mg2+ (Complex from Escherichia coli)
Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-Tyr
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7onu
Q-score: 0.585
Bhatta A, Dienemann C, Cramer P, Hillen HS
Nat Struct Mol Biol (2021) 28 pp. 713-723 [ DOI: doi:10.1038/s41594-021-00637-y Pubmed: 34489609 ]
- Magnesium ion (24 Da, Ligand)
- 3-hydroxyacyl-coa dehydrogenase type-2 (26 kDa, Protein from Homo sapiens)
- Mitochondrial precursor trna-tyr (41 kDa, RNA from Homo sapiens)
- Mitochondrial ribonuclease p catalytic subunit (62 kDa, Protein from Homo sapiens)
- Human mitochondrial rnase p complex with precursor trna-tyr substrate (254 kDa, Complex)
- Zinc ion (65 Da, Ligand)
- Human mitochondrial rnase p complex with precursor mitochondrial trna-tyr (Complex from Homo sapiens)
- Trna methyltransferase 10 homolog c (42 kDa, Protein from Homo sapiens)
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
Cryo-EM structure of human Ribonuclease P
Resolution: 3.92 Å
EM Method: Single-particle
Fitted PDBs: 6ahr
Q-score: 0.224
Wu J, Niu S, Tan M, Huang C, Li M, Song Y, Wang Q, Chen J, Shi S, Lan P, Lei M
Cell (2018) 175 pp. 1393-1404.e11 [ DOI: doi:10.1016/j.cell.2018.10.003 Pubmed: 30454648 ]
- Ribonuclease p protein subunit p20 (15 kDa, Protein from Homo sapiens)
- Ribonucleases p/mrp protein subunit pop1 (114 kDa, Protein from Homo sapiens)
- Rnase p (Complex from Homo sapiens)
- H1 rna (110 kDa, RNA from Homo sapiens)
- Ribonuclease p protein subunit p21 (17 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p29 (25 kDa, Protein from Homo sapiens)
- Ribonuclease p/mrp protein subunit pop5 (18 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p38 (31 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p30 (29 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p14 (13 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p40 (41 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Ribonuclease p protein subunit p25 (20 kDa, Protein from Homo sapiens)
Cryo-EM structure of human Ribonuclease P with mature tRNA
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 6ahu
Q-score: 0.288
Wu J, Niu S, Tan M, Huang C, Li M, Song Y, Wang Q, Chen J, Shi S, Lan P, Lei M
Cell (2018) 175 pp. 1393-1404.e11 [ DOI: doi:10.1016/j.cell.2018.10.003 Pubmed: 30454648 ]
- Ribonuclease p protein subunit p20 (15 kDa, Protein from Homo sapiens)
- Ribonucleases p/mrp protein subunit pop1 (114 kDa, Protein from Homo sapiens)
- Trna (23 kDa, RNA from Homo sapiens)
- Rnase p (Complex from Homo sapiens)
- Rna (Complex from Homo sapiens)
- H1 rna (110 kDa, RNA from Homo sapiens)
- Ribonuclease p protein subunit p21 (17 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p29 (25 kDa, Protein from Homo sapiens)
- Ribonuclease p/mrp protein subunit pop5 (18 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p38 (31 kDa, Protein from Homo sapiens)
- Rnase p with trna (Complex)
- Ribonuclease p protein subunit p30 (29 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p14 (13 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p40 (41 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Ribonuclease p protein subunit p25 (20 kDa, Protein from Homo sapiens)
Cryo-EM structure of yeast Ribonuclease P
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 6agb
Q-score: 0.311
Lan P, Tan M, Zhang Y, Niu S, Chen J, Shi S, Qiu S, Wang X, Peng X, Cai G, Cheng H, Wu J, Li G, Lei M
Science (2018) 362 [ DOI: doi:10.1126/science.aat6678 Pubmed: 30262633 ]
- Ribonuclease p protein subunit rpr2 (16 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Rnase p (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Zinc ion (65 Da, Ligand)
- Ribonuclease p/mrp protein subunit pop5 (19 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop8 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Rnases mrp/p 32.9 kda subunit (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease p rna (118 kDa, RNA from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop1 (100 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop7 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop6 (18 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease p/mrp protein subunit rpp1 (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))