EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-150 Fab
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7nd5
Q-score: 0.309
Dejnirattisai W, Zhou D, Ginn HM, Duyvesteyn HME, Supasa P, Case JB, Zhao Y, Walter TS, Mentzer AJ, Liu C, Wang B, Paesen GC, Slon-Campos J, Lopez-Camacho C, Kafai NM, Bailey AL, Chen RE, Ying B, Thompson C, Bolton J, Fyfe A, Gupta S, Tan TK, Gilbert-Jaramillo J, James W, Knight M, Carroll MW, Skelly D, Dold C, Peng Y, Levin R, Dong T, Pollard AJ, Knight JC, Klenerman P, Temperton N, Hall DR, Williams MA, Paterson NG, Bertram FKR, Siebert CA, Clare DK, Howe A, Radecke J, Song Y, Townsend AR, Huang KA, Fry EE, Mongkolsapaya J, Diamond MS, Ren J, Stuart DI, Screaton GR
Cell (2021) 184 pp. 2183- [ DOI: doi:10.1016/j.cell.2021.02.032 Pubmed: 33756110 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike glycoprotein with covox-150 fab (487 kDa, Complex)
- Sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Covox-150 fab light chain (24 kDa, Protein from Homo sapiens)
- Covox-150 fab (Complex from Homo sapiens)
- Covox-150 fab heavy chain (24 kDa, Protein from Homo sapiens)
EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-40 Fab
Resolution: 7.3 Å
EM Method: Single-particle
Fitted PDBs: 7nd6
Q-score: 0.109
Dejnirattisai W, Zhou D, Ginn HM, Duyvesteyn HME, Supasa P, Case JB, Zhao Y, Walter TS, Mentzer AJ, Liu C, Wang B, Paesen GC, Slon-Campos J, Lopez-Camacho C, Kafai NM, Bailey AL, Chen RE, Ying B, Thompson C, Bolton J, Fyfe A, Gupta S, Tan TK, Gilbert-Jaramillo J, James W, Knight M, Carroll MW, Skelly D, Dold C, Peng Y, Levin R, Dong T, Pollard AJ, Knight JC, Klenerman P, Temperton N, Hall DR, Williams MA, Paterson NG, Bertram FKR, Siebert CA, Clare DK, Howe A, Radecke J, Song Y, Townsend AR, Huang KA, Fry EE, Mongkolsapaya J, Diamond MS, Ren J, Stuart DI, Screaton GR
Cell (2021) 184 pp. 2183- [ Pubmed: 33756110 DOI: doi:10.1016/j.cell.2021.02.032 ]
- Covox-158 fab (Complex from Homo sapiens)
- Covox-158 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike glycoprotein with covox-158 fab (485 kDa, Complex)
- Covox-158 fab light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
EM structure of SARS-CoV-2 Spike glycoprotein (one RBD up) in complex with COVOX-253H55L Fab
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7nd9
Q-score: 0.445
Dejnirattisai W, Zhou D, Ginn HM, Duyvesteyn HME, Supasa P, Case JB, Zhao Y, Walter TS, Mentzer AJ, Liu C, Wang B, Paesen GC, Slon-Campos J, Lopez-Camacho C, Kafai NM, Bailey AL, Chen RE, Ying B, Thompson C, Bolton J, Fyfe A, Gupta S, Tan TK, Gilbert-Jaramillo J, James W, Knight M, Carroll MW, Skelly D, Dold C, Peng Y, Levin R, Dong T, Pollard AJ, Knight JC, Klenerman P, Temperton N, Hall DR, Williams MA, Paterson NG, Bertram FKR, Siebert CA, Clare DK, Howe A, Radecke J, Song Y, Townsend AR, Huang KA, Fry EE, Mongkolsapaya J, Diamond MS, Ren J, Stuart DI, Screaton GR
Cell (2021) 184 pp. 2183- [ DOI: doi:10.1016/j.cell.2021.02.032 Pubmed: 33756110 ]
- Covox-253h55l fab heavy chain (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike glycoprotein with covox-253h55l fab (Complex)
- Sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Covox-253h55l fab (Complex from Homo sapiens)
- Covox-253h55l fab light chain (24 kDa, Protein from Homo sapiens)
EM structure of SARS-CoV-2 Spike glycoprotein (all RBD down) in complex with COVOX-253H55L Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7nda
Q-score: 0.35
Dejnirattisai W, Zhou D, Ginn HM, Duyvesteyn HME, Supasa P, Case JB, Zhao Y, Walter TS, Mentzer AJ, Liu C, Wang B, Paesen GC, Slon-Campos J, Lopez-Camacho C, Kafai NM, Bailey AL, Chen RE, Ying B, Thompson C, Bolton J, Fyfe A, Gupta S, Tan TK, Gilbert-Jaramillo J, James W, Knight M, Carroll MW, Skelly D, Dold C, Peng Y, Levin R, Dong T, Pollard AJ, Knight JC, Klenerman P, Temperton N, Hall DR, Williams MA, Paterson NG, Bertram FKR, Siebert CA, Clare DK, Howe A, Radecke J, Song Y, Townsend AR, Huang KA, Fry EE, Mongkolsapaya J, Diamond MS, Ren J, Stuart DI, Screaton GR
Cell (2021) 184 pp. 2183- [ Pubmed: 33756110 DOI: doi:10.1016/j.cell.2021.02.032 ]
- Covox-253h55l fab heavy chain (25 kDa, Protein from Homo sapiens)
- Covox-253h55l fab light chain (24 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Covox-253h55l fab (Complex from Homo sapiens)
- Complex of sars-cov-2 spike glycoprotein with covox-253h55l fab (491 kDa, Complex)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)