Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"SARS-CoV-2 Spike in complex with 12-C9 Fab" AND xref_links:"chembl" AND author_name:"Cai Y" AND xref_links:"chebi"

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EMD-24192

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SARS-CoV-2 Spike (2P) in complex with C12C9 Fab (NTD local reconstruction)

Release date: Aug. 4, 2021
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7n62
Q-score: 0.428

Tong P, Gautam A, Windsor I, Travers M, Chen Y, Garcia N, Whiteman NB, McKay LGA, Lelis FJN, Habibi S, Cai Y, Rennick LJ, Duprex WP, McCarthy KR, Lavine CL, Zuo T, Lin J, Zuiani A, Feldman J, MacDonald EA, Hauser BM, Griffths A, Seaman MS, Schmidt AG, Chen B, Neuberg D, Bajic G, Harrison SC, Wesemann DR

bioRxiv (2021) [ Pubmed: 33758863 DOI: doi:10.1101/2021.03.10.434840 ]

Sample:

2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
C12c9 fab light chain (23 kDa, Protein from Homo sapiens)
Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Sars-cov-2 spike in complex with 12-c9 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
C12c9 fab heavy chain (24 kDa, Protein from Homo sapiens)

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