Yeast VO in complex with Vma12-22p
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8eas
Q-score: 0.606
Wang H, Bueler SA, Rubinstein JL
PNAS (2023) 120 pp. e2217181120-e2217181120 [ DOI: doi:10.1073/pnas.2217181120 Pubmed: 36724250 ]
- V-type proton atpase subunit e (8 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase assembly factor vma12p (16 kDa, Protein from Saccharomyces cerevisiae)
- Yeast v-atpase subunit f (9 kDa, Protein from Saccharomyces cerevisiae)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae)
- Yeast vo in complex with vma12-22p (Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit a, vacuolar isoform (95 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar atpase assembly protein vma22 (21 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae)
Yeast VO missing subunits a, e, and f in complex with Vma12-22p
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8eat
Q-score: 0.529
Wang H, Bueler SA, Rubinstein JL
PNAS (2023) 120 pp. e2217181120-e2217181120 [ Pubmed: 36724250 DOI: doi:10.1073/pnas.2217181120 ]
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar atpase assembly protein vma22 (21 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar atpase assembly integral membrane protein vph2 (25 kDa, Protein from Saccharomyces cerevisiae)
- Yeast vo missing subunits a, e, and f in complex with vma12-22p (Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae)
Yeast VO in complex with Vma21p
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8eau
Q-score: 0.518
Wang H, Bueler SA, Rubinstein JL
PNAS (2023) 120 pp. e2217181120-e2217181120 [ DOI: doi:10.1073/pnas.2217181120 Pubmed: 36724250 ]
- V-type proton atpase subunit e (8 kDa, Protein from Saccharomyces cerevisiae)
- Yeast v-atpase subunit f (9 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar atpase assembly integral membrane protein vma21 (8 kDa, Protein from Saccharomyces cerevisiae)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit a, vacuolar isoform (95 kDa, Protein from Saccharomyces cerevisiae)
- Yeast vo in complex with vma21p (Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae)
V-ATPase from Saccharomyces cerevisiae, State 3
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7tmt
Q-score: 0.408
Vasanthakumar T, Keon KA, Bueler SA, Jaskolka MC, Rubinstein JL
Nat Struct Mol Biol (2022) 29 pp. 430-439 [ Pubmed: 35469063 DOI: doi:10.1038/s41594-022-00757-z ]
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit a, vacuolar isoform (95 kDa, Protein from Saccharomyces cerevisiae)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar proton pump subunit b (57 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit e (8 kDa, Protein from Saccharomyces cerevisiae)
- Yeast v-atpase subunit f (9 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae)
- H(+)-transporting two-sector atpase (67 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit g (12 kDa, Protein from Saccharomyces cerevisiae)
- V-atpase subunit e (26 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- V-type proton atpase subunit h (54 kDa, Protein from Saccharomyces cerevisiae)
- V-atpase, state 3 (990 kDa, Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (29 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (44 kDa, Protein from Saccharomyces cerevisiae)
V-ATPase from Saccharomyces cerevisiae, State 1
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7tmr
Q-score: 0.45
Vasanthakumar T, Keon KA, Bueler SA, Jaskolka MC, Rubinstein JL
Nat Struct Mol Biol (2022) 29 pp. 430-439 [ Pubmed: 35469063 DOI: doi:10.1038/s41594-022-00757-z ]
- V-atpase, state 1 (990 kDa, Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit e (26 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit a, vacuolar isoform (95 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar proton pump subunit b (57 kDa, Protein from Saccharomyces cerevisiae)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit e (8 kDa, Protein from Saccharomyces cerevisiae)
- Yeast v-atpase subunit f (9 kDa, Protein from Saccharomyces cerevisiae)
- H(+)-transporting two-sector atpase (67 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit g (12 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- V-type proton atpase subunit h (54 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (29 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (44 kDa, Protein from Saccharomyces cerevisiae)
V-ATPase from Saccharomyces cerevisiae, State 2
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7tms
Q-score: 0.431
Vasanthakumar T, Keon KA, Bueler SA, Jaskolka MC, Rubinstein JL
Nat Struct Mol Biol (2022) 29 pp. 430-439 [ Pubmed: 35469063 DOI: doi:10.1038/s41594-022-00757-z ]
- V-type proton atpase subunit h (54 kDa, Protein from Saccharomyces cerevisiae)
- V-atpase, state 2 (990 kDa, Complex from Saccharomyces cerevisiae)
- Vacuolar proton pump subunit b (57 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae)
- H(+)-transporting two-sector atpase (67 kDa, Protein from Saccharomyces cerevisiae)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit e (8 kDa, Protein from Saccharomyces cerevisiae)
- Yeast v-atpase subunit f (9 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit g (12 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae)
- V-atpase subunit e (26 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (44 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (29 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit a, vacuolar isoform (95 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae)
Cryo-EM structure of bafilomycin A1 bound to yeast VO V-ATPase
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7tao
Q-score: 0.491
Keon KA, Benlekbir S, Kirsch SH, Muller R, Rubinstein JL
ACS Chem Biol (2022) 17 pp. 619-628 [ Pubmed: 35148071 DOI: doi:10.1021/acschembio.1c00894 ]
- (5r)-2,4-dideoxy-1-c-{(2s,3r,4s)-3-hydroxy-4-[(2r,3s,4e,6e,9r,10s,11r,12e,14z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl]pentan-2-yl}-4-methyl-5-propan-2-yl-alpha-d-threo-pentopyranose (622 Da, Ligand)
- V-type proton atpase subunit d (39 kDa, Protein from baker's yeast)
- V-type proton atpase subunit c'' (22 kDa, Protein from baker's yeast)
- V-type proton atpase subunit c (16 kDa, Protein from baker's yeast)
- V-type proton atpase subunit c' (17 kDa, Protein from baker's yeast)
- V-type proton atpase subunit e (8 kDa, Protein from baker's yeast)
- Cryo-em structure of bafilomycin a1 bound to yeast vo v-atpase (Complex from Saccharomyces cerevisiae)
- V0 assembly protein 1 (29 kDa, Protein from baker's yeast)
- Yeast v-atpase subunit f (9 kDa, Protein from baker's yeast)
- V-type proton atpase subunit a, vacuolar isoform (95 kDa, Protein from baker's yeast)
Cryo-EM structure of archazolid A bound to yeast VO V-ATPase
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7tap
Q-score: 0.587
Keon KA, Benlekbir S, Kirsch SH, Muller R, Rubinstein JL
ACS Chem Biol (2022) 17 pp. 619-628 [ Pubmed: 35148071 DOI: doi:10.1021/acschembio.1c00894 ]
- V-type proton atpase subunit c' (17 kDa, Protein from baker's yeast)
- V-type proton atpase subunit d (39 kDa, Protein from baker's yeast)
- V-type proton atpase subunit c (16 kDa, Protein from baker's yeast)
- Yeast v-atpase subunit f (9 kDa, Protein from baker's yeast)
- V0 assembly protein 1 (29 kDa, Protein from baker's yeast)
- V-type proton atpase subunit c'' (22 kDa, Protein from baker's yeast)
- V-type proton atpase subunit e (8 kDa, Protein from baker's yeast)
- Cryo-em structure of archazolid a bound to yeast vo v-atpase (Complex from Saccharomyces cerevisiae)
- Archazolid a (739 Da, Ligand)
- V-type proton atpase subunit a, vacuolar isoform (95 kDa, Protein from baker's yeast)
CryoEM Structure of Reconstituted V-ATPase, state1
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7fda
Q-score: 0.205
Khan MM, Lee S, Oot RA, Couoh-Cardel S, Kim H, Wilkens S, Roh SH
EMBO J (2021) [ ]
- V-type proton atpase subunit c (44 kDa, Protein from Saccharomyces cerevisiae S288C)
- Yeast vacuolar atpase a subunit (67 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- Fusion of yeast v-type proton atpase subunit h(nt) and human v-type proton atpase subunit h(ct) (53 kDa, Protein from Homo sapiens)
- Yeast vacuolar atpase in rotary state 1 (1 MDa, Complex from Saccharomyces cerevisiae S288c)
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae S288C)
- Yeast vacuolar atpase a subunit (95 kDa, Protein from Saccharomyces cerevisiae S288C)
- Yeast vacuolar atpase f subunit (9 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit e (8 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit e (26 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit g (13 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunits (Complex)
- Yeast v-type proton atpase subunit c (Complex from Saccharomyces cerevisiae S288c)
- V-type proton atpase subunit d (29 kDa, Protein from Saccharomyces cerevisiae S288C)
- Chimeric subunit h (Complex from Saccharomyces cerevisiae S288c)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit b (57 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae S288C)
CryoEM Structures of Reconstituted V-ATPase,State2
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7fdb
Q-score: 0.043
Khan MM, Lee S, Oot RA, Couoh-Cardel S, Kim H, Wilkens S, Roh SH
EMBO J (2021) [ ]
- V-type proton atpase subunit c (44 kDa, Protein from Saccharomyces cerevisiae S288C)
- Yeast vacuolar atpase a subunit (67 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- Fusion of yeast v-type proton atpase subunit h(nt) and human v-type proton atpase subunit h(ct) (53 kDa, Protein from Homo sapiens)
- Yeast vacuolar atpase in rotary state 2 (1 MDa, Complex from Saccharomyces cerevisiae S288c)
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae S288C)
- Yeast vacuolar atpase a subunit (95 kDa, Protein from Saccharomyces cerevisiae S288C)
- Yeast vacuolar atpase f subunit (9 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit e (8 kDa, Protein from Saccharomyces cerevisiae S288C)
- Yeast vacuolar atpase c subunit (Complex from Saccharomyces cerevisiae S288c)
- V-type proton atpase subunit e (26 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit g (13 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunits (Complex)
- V-type proton atpase subunit d (29 kDa, Protein from Saccharomyces cerevisiae S288C)
- Chimeric subunit h (Complex from Saccharomyces cerevisiae S288c)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit b (57 kDa, Protein from Saccharomyces cerevisiae S288C)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae S288C)