NorA double mutant - E222QD307N at pH 7.5
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 8ttf
Q-score: 0.427
Li JP, Li Y, Koide A, Kuang HH, Torres VJ, Koide S, Wang DN, Traaseth NJ
To Be Published
- Heavy chain of fabda1 variable domain (14 kDa, Protein from Homo sapiens)
- E222qd307n-nora:fabda1 (100 kDa, Complex from Staphylococcus aureus)
- Quinolone resistance protein nora (46 kDa, Protein from Staphylococcus aureus)
- Light chain of fabda1 variable domain (11 kDa, Protein from Homo sapiens)
NorA single mutant - D307N at pH 7.5
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8tth
Q-score: 0.413
Li JP, Li Y, Koide A, Kuang HH, Torres VJ, Koide S, Wang DN, Traaseth NJ
To Be Published
- D307n-nora:fabda1 (100 kDa, Complex from Staphylococcus aureus)
- Heavy chain of fabda1 variable domain (14 kDa, Protein from Homo sapiens)
- Light chain of fabda1 variable domain (11 kDa, Protein from Homo sapiens)
- Quinolone resistance protein nora (46 kDa, Protein from Staphylococcus aureus)
Cryo-EM structure of human NTCP-Bulevirtide complex
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8rqf
Q-score: 0.492
Liu H, Zakrzewicz D, Nosol K, Irobalieva RN, Mukherjee S, Bang-Sorensen R, Goldmann N, Kunz S, Rossi L, Kossiakoff AA, Urban S, Glebe D, Geyer J, Locher KP
To Be Published
- Polymerase (5 kDa, Protein from hepatitis B virus genotype C)
- Light chain of fab3 (23 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Sodium/bile acid cotransporter (38 kDa, Protein from Homo sapiens)
- N-tetradecanoylglycine (285 Da, Ligand)
- Heavy chain of fab3 (25 kDa, Protein from Homo sapiens)
- Structure of bulevirtide-bound human ntcp in complex with fab and nanobody (110 kDa, Complex from Homo sapiens)
- Fab-specific nanobody (13 kDa, Protein from Lama glama)
H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting 1-1-1F05
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8tp2
Q-score: 0.541
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB
bioRxiv (2023) [ Pubmed: 37781590 DOI: doi:10.1101/2023.08.23.554525 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of fab 1-1-1f05 (11 kDa, Protein from Homo sapiens)
- Heavy chain of fab 1-1-1f05 (13 kDa, Protein from Homo sapiens)
- H2 hemagglutinin (a/singapore/1/1957) in complex with rbs-targeting fab 1-1-1f05 (Complex from Influenza A virus (A/Singapore/1/1957(H2N2)))
- Hemagglutinin (57 kDa, Protein from Homo sapiens)
H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1F05
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8tp3
Q-score: 0.38
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB
bioRxiv (2023) [ Pubmed: 37781590 DOI: doi:10.1101/2023.08.23.554525 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin ha1 chain (38 kDa, Protein from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- H1 hemagglutinin (nc99) in complex with sa-targeting fab 1-1-1f05 (Complex from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- Heavy chain of fab 1-1-1f05 (13 kDa, Protein from Homo sapiens)
- Light chain of fab 1-1-1f05 (11 kDa, Protein from Homo sapiens)
H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting Fab 1-1-1E04
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8tp4
Q-score: 0.516
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB
bioRxiv (2023) [ Pubmed: 37781590 DOI: doi:10.1101/2023.08.23.554525 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin (57 kDa, Protein from Influenza A virus (A/Singapore/1/1957(H2N2)))
- Heavy chain of fab 1-1-1e04 (14 kDa, Protein from Homo sapiens)
- H2 hemagglutinin (a/singapore/1/1957) in complex with rbs-targeting fab 1-1-1e04 (Complex from Influenza A virus (A/Singapore/1/1957(H2N2)))
- Light chain of fab 1-1-1e04 (13 kDa, Protein from Homo sapiens)
H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1E04
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8tp5
Q-score: 0.505
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB
bioRxiv (2023) [ Pubmed: 37781590 DOI: doi:10.1101/2023.08.23.554525 ]
- H1 hemagglutinin (nc99) in complex with rbs-targeting fab 1-1-1e04 (Complex from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of fab 1-1-1e04 (14 kDa, Protein from Homo sapiens)
- Hemagglutinin ha1 chain (35 kDa, Protein from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- Hemagglutinin ha2 chain (19 kDa, Protein from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- Light chain of fab 1-1-1e04 (11 kDa, Protein from Homo sapiens)
H2 hemagglutinin (A/Singapore/1/1957) in complex with medial-junction-targeting Fab 2-2-1G06
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8tp9
Q-score: 0.476
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB
bioRxiv (2023) [ Pubmed: 37781590 DOI: doi:10.1101/2023.08.23.554525 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin (57 kDa, Protein from Influenza A virus (A/Singapore/1/1957(H2N2)))
- Light chain of fab 2-2-1g06 (11 kDa, Protein from Homo sapiens)
- Heavy chain of fab 2-2-1g06 (14 kDa, Protein from Homo sapiens)
- H2 hemagglutinin (a/singapore/1/1957) in complex with medial-junction-targeting fab 2-2-1g06 (Complex from Influenza A virus (A/Singapore/1/1957(H2N2)))
H1 hemagglutinin (NC99) in complex with medial-junction-targeting Fab 2-2-1G06
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8tpa
Q-score: 0.524
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB
bioRxiv (2023) [ Pubmed: 37781590 DOI: doi:10.1101/2023.08.23.554525 ]
- H1 hemagglutinin (nc99) in complex with medial-junction-targeting fab 2-2-1g06 (Complex from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- Light chain of fab 2-2-1g06 (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin ha1 chain (38 kDa, Protein from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- Heavy chain of fab 2-2-1g06 (14 kDa, Protein from Homo sapiens)
Local CryoEM structure of the SARS-CoV-2 S6P in complex with 14B1 Fab
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8i3u
Q-score: 0.462
Liu Q, Zhao H, Li Z, Zhang Z, Huang R, Gu M, Zhuang K, Xiong Q, Chen X, Yu W, Qian S, Zhang Y, Tan X, Zhang M, Yu F, Guo M, Huang Z, Wang X, Xiang W, Wu B, Mei F, Cai K, Zhou L, Zhou L, Wu Y, Yan H, Cao S, Lan K, Chen Y
Signal Transduct Target Ther (2023) 8 pp. 347-347 [ DOI: doi:10.1038/s41392-023-01615-0 Pubmed: 37704615 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of fab 14b1 (14 kDa, Protein from Homo sapiens)
- Heavy chain of fab 14b1 (16 kDa, Protein from Homo sapiens)
- Spike glycoprotein (137 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Spike-fab complex (Complex from Severe acute respiratory syndrome coronavirus 2)