Heparin bound Tau fibril polymorph 3
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8zwl
Q-score: 0.541
To Be Published
Heparin bound Tau fibril polymorph 4
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8zwm
Q-score: 0.591
To Be Published
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 8zx6
Q-score: 0.545
To Be Published
AT8-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S202E, T205E, S208E)
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ttl
Q-score: 0.598
Mammeri NE, Dregni AJ, Duan P, Hong M
PNAS (2024) 121 pp. e2316175121-e2316175121 [ Pubmed: 38408247 DOI: doi:10.1073/pnas.2316175121 ]
- Microtubule-associated protein tau (40 kDa, Protein from Homo sapiens)
- At8-phosphomimetic 0n4r tau fibrils (Complex from Homo sapiens)
PHF1-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S396E, S400E, T403E, S404E)
Resolution: 2.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ttn
Q-score: 0.574
Mammeri NE, Dregni AJ, Duan P, Hong M
PNAS (2024) 121 pp. e2316175121-e2316175121 [ Pubmed: 38408247 DOI: doi:10.1073/pnas.2316175121 ]
- Microtubule-associated protein tau (40 kDa, Protein from Homo sapiens)
- Phf1-phosphomimetic 0n4r tau fibrils (Complex from Homo sapiens)
KIF1A[1-393] AMP-PNP bound two-heads-bound state in complex with a microtubule (class T23L1)
Benoit MPMH, Rao L, Asenjo AB, Gennerich A, Sosa H
To Be Published
- Kif1a - amp-pnp two-heads-bound state in complex with a microtubule (class t23ls) (Complex)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Taxol (853 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Kinesin-like protein kif1a (49 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
KIF1A[1-393] AMP-PNP bound two-heads-bound state in complex with a microtubule - class T2L1
Benoit MPMH, Rao L, Asenjo AB, Gennerich A, Sosa H
To Be Published
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Kif1a - amp-pnp two-heads-bound state in complex with a microtubule - class t2ls (Complex)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Kif1a - amp-pnp (Complex from Homo sapiens)
- Taxol (853 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Kinesin-like protein kif1a (49 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Microtubule (Complex from Sus scrofa)
KIF1A[1-393] - AMP-PNP two-heads-bound state in complex with a microtubule - class T3L1
Benoit MPMH, Rao L, Asenjo AB, Gennerich A, Sosa H
To Be Published
- Taxol (853 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Kinesin-like protein kif1a (49 kDa, Protein from Homo sapiens)
- Kif1a - amp-pnp two-heads-bound state in complex with a microtubule - class t3ls (Complex)
KIF1A[1-393] AMP-PNP bound one-head-bound state in complex with a microtubule - class T1L02*
Benoit MPMH, Rao L, Asenjo AB, Gennerich A, Sosa H
To Be Published
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Taxol (853 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Kinesin-like protein kif1a (49 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Kif1a - amp-pnp one-head-bound state in complex with a 15r microtubule - class t1l02* (Complex)
KIF1A[1-393] ADP bound in complex with a microtubule
Benoit MPMH, Rao L, Asenjo AB, Gennerich A, Sosa H
To Be Published
- Tubulin beta-2b chain (49 kDa, Protein from Sus scrofa)
- Taxol (853 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Kinesin-like protein kif1a (49 kDa, Protein from Homo sapiens)
- Kif1a[1-393] adp in complex with a 15r microtubule (Complex)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)