Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"nonane" AND assembly_molecular_weight:{250000 TO 500000] AND resolution:[4 TO 5}

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EMD-22049

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Asymmetric reconstruction of CD4- and 17b-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52

Release date: Oct. 21, 2020
Resolution: 4.04 Å
EM Method: Single-particle
Fitted PDBs: 6x5c
Q-score: 0.341

Ozorowski G, Torres JL, Santos-Martins D, Forli S, Ward AB

Cell Rep (2020) 33 pp. 108428-108428 [ DOI: doi:10.1016/j.celrep.2020.108428 Pubmed: 33238117 ]

Sample:

B41 hiv-1 env sosip in complex with soluble cd4, 17b fab, and small molecule go52 (630 kDa, Complex from Human immunodeficiency virus 1)
2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
Envelope glycoprotein gp160 (58 kDa, Protein from Human immunodeficiency virus 1)
N-(4'-methyl[1,1'-biphenyl]-4-yl)-1-oxa-7-azaspiro[3.5]nonane-7-carboxamide (336 Da, Ligand)
T-cell surface glycoprotein cd4 (23 kDa, Protein from Homo sapiens)

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