structure of a membrane-bound glycosyltransferase
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7xe4
Q-score: 0.471
Hu X, Yang P, Chai C, Liu J, Sun H, Wu Y, Zhang M, Zhang M, Liu X, Yu H
Nature (2023) 616 pp. 190-198 [ Pubmed: 36949198 DOI: doi:10.1038/s41586-023-05856-5 ]
- 1,3-beta-glucan synthase component fks1 (215 kDa, Protein from baker's yeast)
- Heptane (100 Da, Ligand)
- Dodecane (170 Da, Ligand)
- (11r,14s)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate (495 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- Membrane-bound glycosyltransferase (215 kDa, Complex from Saccharomyces cerevisiae)
- Nonane (128 Da, Ligand)
- Decane (142 Da, Ligand)
Structure of a mutated membrane-bound glycosyltransferase
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7yuy
Q-score: 0.494
Hu X, Yang P, Chai C, Liu J, Sun H, Wu Y, Zhang M, Zhang M, Liu X, Yu H
Nature (2023) 616 pp. 190-198 [ Pubmed: 36949198 DOI: doi:10.1038/s41586-023-05856-5 ]
- Membrane-bound glycosyltransferase (215 kDa, Complex from Saccharomyces cerevisiae)
- Dodecane (170 Da, Ligand)
- Decane (142 Da, Ligand)
- Heptane (100 Da, Ligand)
- 1,3-beta-glucan synthase component fks1 (215 kDa, Protein from Saccharomyces cerevisiae)
- Nonane (128 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- (11r,14s)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate (495 Da, Ligand)
Cryo-EM reveals partially and fully assembled native glycine receptors,heteromeric pentamer
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7mly
Q-score: 0.49
Nature (2021) 599 pp. 513-517 [ DOI: doi:10.1038/s41586-021-04022-z Pubmed: 34555840 ]
- Pentane (72 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Native heteromeric glycine receptor bound with 3d1 fab (500 kDa, Complex)
- Hexane (86 Da, Ligand)
- Decane (142 Da, Ligand)
- Heptane (100 Da, Ligand)
- Glycine receptor beta (56 kDa, Protein from Pig)
- N-butane (58 Da, Ligand)
- N-octane (114 Da, Ligand)
- Glycine receptor alpha 1 (51 kDa, Protein from Pig)
- Pentadecane (212 Da, Ligand)
- Undecane (156 Da, Ligand)
- 3d1 fab (Complex from Rattus norvegicus)
- Nonane (128 Da, Ligand)
- Native heteromeric glycine receptor (Complex from Sus scrofa)
- Glycine (75 Da, Ligand)
- 3d1 fab light chain (11 kDa, Protein from Rattus norvegicus)
- 3d1 fab heavy chain (12 kDa, Protein from Rattus norvegicus)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7ldd
Q-score: 0.25
Yu J, Rao P, Clark S, Mitra J, Ha T, Gouaux E
Nature (2021) 594 pp. 448-453 [ Pubmed: 33981040 DOI: doi:10.1038/s41586-021-03540-0 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Protein cornichon homolog 2 (18 kDa, Protein from Mouse)
- Heptane (100 Da, Ligand)
- Nonane (128 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- Glutamate receptor 1 (101 kDa, Protein from Mouse)
- Dodecane (170 Da, Ligand)
- Glua1/a2-symmetric-conformation bound to antibody fragments (Complex)
- Voltage-dependent calcium channel gamma-8 subunit (43 kDa, Protein from Mouse)
- {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2h)-yl]methyl}phosphonic acid (409 Da, Ligand)
- 11b8 scfv (27 kDa, Protein from Mus musculus)
- Decane (142 Da, Ligand)
- 15f1 fab light chain (25 kDa, Protein from Mus musculus)
- N-octane (114 Da, Ligand)
- Glua1/a2-symmetric-conformation (Complex from Mus musculus)
- 15f1 fab heavy chain (27 kDa, Protein from Mus musculus)
- 15f1 fab (Complex from Mus musculus)
- 11b8 scfv (Complex from Mus musculus)
- Hexadecane (226 Da, Ligand)
- Glutamate receptor (98 kDa, Protein from Mouse)
- 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1h-benzimidazol-2-ol (328 Da, Ligand)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7lde
Q-score: 0.221
Yu J, Rao P, Clark S, Mitra J, Ha T, Gouaux E
Nature (2021) 594 pp. 448-453 [ DOI: doi:10.1038/s41586-021-03540-0 Pubmed: 33981040 ]
- Glua1/a2-asymmetric-conformation (Complex from Mus musculus)
- {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2h)-yl]methyl}phosphonic acid (409 Da, Ligand)
- Heptane (100 Da, Ligand)
- Dodecane (170 Da, Ligand)
- N-octane (114 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 11b8 scfv (Complex from Mus musculus)
- Glua1/a2-asymmetric-conformation bound to antibody fragments (Complex)
- Glutamate receptor 1 (101 kDa, Protein from Mouse)
- 15f1 fab heavy chain (27 kDa, Protein from Mus musculus)
- 15f1 fab (Complex from Mus musculus)
- Nonane (128 Da, Ligand)
- 15f1 fab light chain (25 kDa, Protein from Mus musculus)
- Glutamate receptor (98 kDa, Protein from Mouse)
- Tetradecane (198 Da, Ligand)
- 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1h-benzimidazol-2-ol (328 Da, Ligand)
- Hexadecane (226 Da, Ligand)
- Protein cornichon homolog 2 (18 kDa, Protein from Mouse)
- Voltage-dependent calcium channel gamma-8 subunit (43 kDa, Protein from Mouse)
- 11b8 scfv (27 kDa, Protein from Mus musculus)
- Decane (142 Da, Ligand)