Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7ldd
Q-score: 0.25
Yu J, Rao P, Clark S, Mitra J, Ha T, Gouaux E
Nature (2021) 594 pp. 448-453 [ Pubmed: 33981040 DOI: doi:10.1038/s41586-021-03540-0 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Protein cornichon homolog 2 (18 kDa, Protein from Mouse)
- Heptane (100 Da, Ligand)
- Nonane (128 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- Glutamate receptor 1 (101 kDa, Protein from Mouse)
- Dodecane (170 Da, Ligand)
- Glua1/a2-symmetric-conformation bound to antibody fragments (Complex)
- Voltage-dependent calcium channel gamma-8 subunit (43 kDa, Protein from Mouse)
- {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2h)-yl]methyl}phosphonic acid (409 Da, Ligand)
- 11b8 scfv (27 kDa, Protein from Mus musculus)
- Decane (142 Da, Ligand)
- 15f1 fab light chain (25 kDa, Protein from Mus musculus)
- N-octane (114 Da, Ligand)
- Glua1/a2-symmetric-conformation (Complex from Mus musculus)
- 15f1 fab heavy chain (27 kDa, Protein from Mus musculus)
- 15f1 fab (Complex from Mus musculus)
- 11b8 scfv (Complex from Mus musculus)
- Hexadecane (226 Da, Ligand)
- Glutamate receptor (98 kDa, Protein from Mouse)
- 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1h-benzimidazol-2-ol (328 Da, Ligand)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7lde
Q-score: 0.221
Yu J, Rao P, Clark S, Mitra J, Ha T, Gouaux E
Nature (2021) 594 pp. 448-453 [ DOI: doi:10.1038/s41586-021-03540-0 Pubmed: 33981040 ]
- Glua1/a2-asymmetric-conformation (Complex from Mus musculus)
- {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2h)-yl]methyl}phosphonic acid (409 Da, Ligand)
- Heptane (100 Da, Ligand)
- Dodecane (170 Da, Ligand)
- N-octane (114 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 11b8 scfv (Complex from Mus musculus)
- Glua1/a2-asymmetric-conformation bound to antibody fragments (Complex)
- Glutamate receptor 1 (101 kDa, Protein from Mouse)
- 15f1 fab heavy chain (27 kDa, Protein from Mus musculus)
- 15f1 fab (Complex from Mus musculus)
- Nonane (128 Da, Ligand)
- 15f1 fab light chain (25 kDa, Protein from Mus musculus)
- Glutamate receptor (98 kDa, Protein from Mouse)
- Tetradecane (198 Da, Ligand)
- 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1h-benzimidazol-2-ol (328 Da, Ligand)
- Hexadecane (226 Da, Ligand)
- Protein cornichon homolog 2 (18 kDa, Protein from Mouse)
- Voltage-dependent calcium channel gamma-8 subunit (43 kDa, Protein from Mouse)
- 11b8 scfv (27 kDa, Protein from Mus musculus)
- Decane (142 Da, Ligand)
Human alpha3beta4 nicotinic acetylcholine receptor in complex with nicotine
Resolution: 3.34 Å
EM Method: Single-particle
Fitted PDBs: 6pv7
Q-score: 0.501
Gharpure A, Teng J, Zhuang Y, Noviello CM, Walsh Jr RM, Cabuco R, Howard RJ, Zaveri NT, Lindahl E, Hibbs RE
Neuron (2019) 104 pp. 501- [ DOI: doi:10.1016/j.neuron.2019.07.030 Pubmed: 31488329 ]
- Kappa fab light chain (23 kDa, Protein from house mouse)
- Igg2b heavy chain (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human alpha3beta4 nicotinic acetylcholine receptor (Complex)
- Igg2b fab heavy chain (23 kDa, Protein from house mouse)
- Cholesterol hemisuccinate (486 Da, Ligand)
- (s)-3-(1-methylpyrrolidin-2-yl)pyridine (162 Da, Ligand)
- Neuronal acetylcholine receptor subunit beta-4 (Complex)
- Igg2b/kappa antibody (Complex)
- Nonane (128 Da, Ligand)
- Water (18 Da, Ligand)
- Fusion protein of neuronal acetylcholine receptor subunit alpha-3 and soluble cytochrome b562 (60 kDa, Protein from Homo sapiens)
- Human alpha3beta4 nicotinic receptor in complex with fab fragments and bound to nicotine (Complex from Homo sapiens)
- Neuronal acetylcholine receptor subunit alpha-3 (Complex)
- Kappa fab light chain (Complex)
- Fusion protein of neuronal acetylcholine receptor subunit beta-4 and soluble cytochrome b562 (61 kDa, Protein from Homo sapiens)
- Sodium ion (22 Da, Ligand)