EMPIAR-10673

Cryo-EM of GLP-1 receptor bound to GLP-1 and Gs protein

Entry authors:
Zhang X, Belousoff MJ , Zhao P, Kooistra AJ , Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE , Danev R , Sexton PM , Wootten D 
Publication:
Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists
Zhang X, Belousoff MJ , Zhao P, Kooistra AJ , Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE , Danev R , Sexton PM , Wootten D 
Mol Cell 80 485-500.e7 (2020)
PMID: 33027691
Experiment type:
EMDB
Related PDB entry:
Related EMDB entry:
.EMD-21992 (2.1Å)
Deposited:
2021-03-22
Released:
2021-06-04
Last modified:
2021-06-04
Dataset size:
1.9 TB
Experimental metadata:
Contains:
micrographs
Image not available

Image set

1. Non-gain-normalized LZW-TIFF compressed movies of GLP-1R-GLP-1 in a detergent micelle
Category:micrographs - multiframe
Image format:TIFF
No. of images or tilt series:5739
Frames per image:75
Image size:(5760, 4092)
Pixel type:UNSIGNED BYTE
Pixel spacing:(0.83 Å, 0.83 Å)
Details:
.The "Dataset_details_GLP-1R-GLP-1.txt" file contains details about the experiment and the dataset. The gain reference created from the dataset is "GLP-1_gain.mrc". The particles from the last 3D auto-refinement are in the file "GLP-1_data.star".
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