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Project: PRJNA416055

We employ ChIP- seq methodology to study the effect of ionizing radiation on genome-wide localization of acetylated histone H4 Overall design: Antibody used for Acetylated histone H4 bound DNA in radiated and non-radiated LNCaP cells

Organism:

Homo sapiens (human)

Secondary Study Accession:

SRP122487

Study Title:

BRD4 promotes DNA repair and mediates the formation of TMPRSS2-ERG gene rearrangements in prostate cancer

Center Name:

Pathology, UT Southwestern Medical Center

Study Name:

BRD4 promotes DNA repair and mediates the formation of TMPRSS2-ERG gene rearrangements in prostate cancer

ENA-REFSEQ:

PROJECT-ID:

416055

ENA-FIRST-PUBLIC:

2018-03-01

ENA-LAST-UPDATE:

2025-03-01

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Study Accession	Sample Accession	Experiment Accession	Run Accession	Tax Id	Scientific Name	Download All Generated FASTQ files: FTP	Download All Submitted files: FTP	Download All SRA files: FTP	Download All Bam files: FTP
PRJNA416055	SAMN07840561	SRX3337260	SRR6228664	9606	Homo sapiens	SRR6228664.fastq.gz	N/ASubmitted files are only available for data submitted via ENA	SRR6228664	N/A
PRJNA416055	SAMN07840559	SRX3337262	SRR6228666	9606	Homo sapiens	SRR6228666.fastq.gz	N/ASubmitted files are only available for data submitted via ENA	SRR6228666	N/A
PRJNA416055	SAMN07840562	SRX3337259	SRR6228663	9606	Homo sapiens	SRR6228663.fastq.gz	N/ASubmitted files are only available for data submitted via ENA	SRR6228663	N/A
PRJNA416055	SAMN07840560	SRX3337261	SRR6228665	9606	Homo sapiens	SRR6228665.fastq.gz	N/ASubmitted files are only available for data submitted via ENA	SRR6228665	N/A

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PRJNA9558	Human genome projects have generated an unprecedented amount of knowledge about human genetics and h... See more Study of the human condition such as genetic and infectious disease, the intersection between geneti... See more

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Human genome projects have generated an unprecedented amount of knowledge about human genetics and health.

Study of the human condition such as genetic and infectious disease, the intersection between genetics and the environment, and population variation is supported by a wealth of genome-scale data. These data sets include: a) numerous sequenced genomes including several which have been assembled; b) studies that examine transcript and protein existence, abundance, and differential expression; c) epigenomic and functional studies to define regulatory and other sequence elements; and d) population studies to define small and large variations in the genome, transcriptome, proteome, epigenome, or the microbiome. The result is an unprecedented amount of data and knowledge concerning human genetics that will result in breakthroughs in understanding human biology as well as significant medical advances. <p>A challenge facing researchers today is that of analyzing and integrating the plethora of data available. The sequence and other molecular data available provides a critical foundation for continued advances in medicine, basic research, and clinical diagnostic technologies.

Project: PRJNA416055

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