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Gene:
ARL5B
GWAS
Genes
ARL5B
ARL5B
Gene information
Gene name
ARL5B
Description
ADP ribosylation factor like GTPase 5B
Location
10:18659431-18681639
Cytogenetic region
10p12.31
Biotype
protein_coding
Gene in
NCBI
Gene in
Ensembl
Phenotype information
Pathway information
Regulation
Expression
Gene in
Open Targets
Gene in
OMIM
Mouse ortholog in
IMPC
Available data:
Associations
6
Studies
6
Traits
6
Download Associations
Associations
6
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Variant and
risk allele
P-value
P-value
annotation
RAF
OR
Beta
CI
Mapped gene
Reported trait
Trait(s)
Background
trait(s)
Study accession
Location
Variant and
risk allele
P-value
P-value
annotation
RAF
OR
Beta
CI
Mapped gene
Reported trait
Trait(s)
Background
trait(s)
Study accession
Location
rs45593736-A
3 x 10
-8
-
0.02
2.38
-
[1.75-3.23]
ARL5B
Suicide attempts in major depressive disorder
attempted suicide
major depressive disorder
GCST008118
10:18666008
rs10829156-?
4 x 10
-7
(Recessive)
0.20
1.28
-
[1.16-1.41]
ARL5B
Sudden cardiac arrest
sudden cardiac arrest
-
GCST001099
10:18661626
rs11015915-A
9 x 10
-6
-
NR
2.2
-
[1.56-3.12]
ARL5B
,
AIFM1P1
Immunoglobulin A vasculitis
Henoch-Schoenlein purpura
-
GCST004745
10:18724467
rs11015781-A
7 x 10
-6
-
0.3
1.2
-
[0.76-1.91]
AIFM1P1
,
ARL5B
Postoperative atrial fibrillation in coronary artery bypass grafting surgery
atrial fibrillation
coronary artery bypass
GCST002975
10:18705654
rs7922005-?
8 x 10
-8
-
NR
-
-
-
AIFM1P1
,
ARL5B
Height
body height
-
GCST007841
10:18683545
Showing 1 to 5 of 6 entries
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Studies
6
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First author
Study accession
Pub. date
Journal
Title
Reported trait
Trait(s)
Background trait(s)
Discovery sample number
Replication sample number
Association count
Summary statistics
First author
Study accession
Pub. date
Journal
Title
Reported trait
Trait(s)
Background trait(s)
Discovery sample number
Replication sample number
Association count
Summary statistics
Kertai MD
GCST002975
2015-06-17
Am Heart J
Genome-wide association study of new-onset…
Postoperative atrial fibrillation in coronary artery bypass grafting surgery
atrial fibrillation
coronary artery bypass
• 877 European
• 304 NR
3
Not available
López-Mejías R
GCST004745
2017-07-11
Sci Rep
A genome-wide association study suggests the HLA…
Immunoglobulin A vasculitis
Henoch-Schoenlein purpura
-
• 1291 European
7
Not available
Mullins N
GCST008118
2019-06-05
Am J Psychiatry
GWAS of Suicide Attempt in Psychiatric Disorders…
Suicide attempts in major depressive disorder
attempted suicide
major depressive disorder
• 10408 European
20
Not available
Temprano-Sagrera G
GCST90129538
2022-03-14
J Thromb Haemost
Multi-phenotype analyses of hemostatic traits…
Venous thromboembolism or factor XI levels (pleiotropy)
factor XI measurement
,
venous thromboembolism
-
• 16169 European
• 202356 European, African American or Afro-Caribbean
23
Not available
Aouizerat BE
GCST001099
2011-06-10
BMC Cardiovasc Disord
GWAS for discovery and replication of genetic…
Sudden cardiac arrest
sudden cardiac arrest
-
• 605 European
36
Not available
Showing 1 to 5 of 6 entries
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Traits
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Trait label(s)
Reported trait(s)
Association count with ARL5B
Trait label(s)
Reported trait(s)
Association count with ARL5B
Henoch-Schoenlein purpura
Immunoglobulin A vasculitis
1
sudden cardiac arrest
Sudden cardiac arrest
1
attempted suicide
Suicide attempts in major depressive disorder
1
atrial fibrillation
Postoperative atrial fibrillation in coronary artery bypass grafting surgery
1
factor XI measurement
,
venous thromboembolism
Venous thromboembolism or factor XI levels (pleiotropy)
1
Showing 1 to 5 of 6 entries
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1
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