GWAS Catalog

Gene: ERBB3

Gene information

Gene name

ERBB3

Description

erb-b2 receptor tyrosine kinase 3

Location

12:56076799-56103505

Cytogenetic region

Biotype

protein_coding

Available data:

Associations 129

Show entries

Variant and risk allele	P-value	P-value annotation	RAF	OR	Beta	CI	Mapped gene	Reported trait	Trait(s)	Background trait(s)	Study accession	Location

rs877636-?	3 x 10^-7	-	NR	-	0.0313 unit decrease	[0.019-0.043]	ERBB3	Cognitive function	intelligence	-	GCST002774	12:56086799
rs2292239-?	2 x 10^-25	-	NR	-	-	-	ERBB3	Type 1 diabetes	type 1 diabetes mellitus	-	GCST000392	12:56088396
rs11171739-C	1 x 10^-11		0.42	1.34	-	[1.17-1.54]	ERBB3	Type 1 diabetes	type 1 diabetes mellitus	-	GCST000043	12:56076841
rs2292239-A	3 x 10^-16	-	NR	-	-	-	ERBB3	Type 1 diabetes	type 1 diabetes mellitus	-	GCST000258	12:56088396
rs2292239-A	2 x 10^-20		0.34	1.28	-	[1.21-1.35]	ERBB3	Type 1 diabetes	type 1 diabetes mellitus	-	GCST000038	12:56088396

Showing 1 to 5 of 129 entries

Studies127

Show entries

First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Replication sample number	Association count	Summary statistics

First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Replication sample number	Association count	Summary statistics

Salinas YD	GCST011156	2020-07-23	Am J Epidemiol	Discovery and Mediation Analysis of…	Body mass index	body mass index	-	• 305945 European		1	Not available
Katz DH	GCST90137598	2021-11-24	Circulation	Whole Genome Sequence Analysis of the Plasma…	Receptor tyrosine-protein kinase erbB-3 levels	receptor tyrosine-protein kinase erbb-3 measurement	-	• 1852 African American or Afro-Caribbean	• 1688 African American or Afro-Caribbean, Hispanic or Latin American, Asian unspecified, European	1	Not available
Western D	GCST90425389	2024-11-11	Nat Genet	Proteogenomic analysis of human cerebrospinal…	Receptor tyrosine-protein kinase erbB-3 levels	protein measurement	-	• 3506 European		2	FTP Download
Pietzner M	GCST90247488	2021-11-12	Science	Mapping the proteo-genomic convergence of human…	Receptor tyrosine-protein kinase erbB-3 levels	receptor tyrosine-protein kinase erbb-3 measurement	-	• 10708 European		3	Not available
Duncan L	GCST004367	2017-05-12	Am J Psychiatry	Significant Locus and Metabolic Genetic…	Anorexia nervosa	anorexia nervosa	-	• 14477 European		6	Not available

Showing 1 to 5 of 127 entries