GWAS Catalog

Gene: LCE3B

Gene information

Gene name

LCE3B

Description

late cornified envelope 3B

Location

1:152613811-152614098

Cytogenetic region

Biotype

protein_coding

Available data:

Associations 6

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Variant and risk allele	P-value	P-value annotation	RAF	OR	Beta	CI	Mapped gene	Reported trait	Trait(s)	Background trait(s)	Study accession	Location

rs6677595-T	2 x 10^-33	-	0.64	1.26	-	-	LCE3A, LCE3B	Psoriasis	psoriasis	-	GCST005527	1:152617711
rs4845454-T	4 x 10^-12	-	NR	1.164	-	NR	LCE3A, LCE3B	Psoriasis vulgaris	psoriasis vulgaris	-	GCST003268	1:152619708
rs11205044-C	2 x 10^-14	-	NR	1.09	-	-	LCE3A, LCE3B	Psoriasis or type 2 diabetes (trans-disease meta-analysis)(opposite effect)	psoriasis, type 2 diabetes mellitus	-	GCST011990	1:152620961
rs6677595-T	1 x 10^-13	-	NR	1.08	-	NR	LCE3A, LCE3B	Psoriasis or type 2 diabetes (trans-disease meta-analysis)	psoriasis, type 2 diabetes mellitus	-	GCST011991	1:152617711
rs1581803-?	2 x 10^-12	(Psoriasis)	NR	1.22	-	[1.15–1.30]	LCE3A, LCE3B	Inflammatory skin disease	psoriasis	-	GCST002740	1:152619805

Showing 1 to 5 of 6 entries

Studies6

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First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Replication sample number	Association count	Summary statistics

First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Replication sample number	Association count	Summary statistics

Tsoi LC	GCST005527	2012-12-01	Nat Genet	Identification of 15 new psoriasis…	Psoriasis	psoriasis	-	• 33394 European		41	FTP Download
Stuart PE	GCST003268	2015-11-28	Am J Hum Genet	Genome-wide Association Analysis of Psoriatic…	Psoriasis vulgaris	psoriasis vulgaris	-	• 8941 European	• 21801 European	39	Not available
Patrick MT	GCST011991	2020-12-29	J Invest Dermatol	Causal relationship and shared genetic loci…	Psoriasis or type 2 diabetes (trans-disease meta-analysis)	psoriasis, type 2 diabetes mellitus	-	• 925490 European		43	Not available
Patrick MT	GCST011990	2020-12-29	J Invest Dermatol	Causal relationship and shared genetic loci…	Psoriasis or type 2 diabetes (trans-disease meta-analysis)(opposite effect)	psoriasis, type 2 diabetes mellitus	-	• 925490 European		32	Not available
Baurecht H	GCST002740	2015-01-08	Am J Hum Genet	Genome-wide comparative analysis of atopic…	Inflammatory skin disease	inflammatory skin disease	-	• 18190 European		88	Not available

Showing 1 to 5 of 6 entries