GWAS Catalog

Gene: PRDM8

Gene information

Gene name

PRDM8

Description

PR/SET domain 8

Location

4:80183879-80204329

Cytogenetic region

Biotype

protein_coding

Available data:

Associations 372

Show entries

Variant and risk allele	P-value	P-value annotation	RAF	OR	Beta	CI	Mapped gene	Reported trait	Trait(s)	Background trait(s)	Study accession	Location

rs1996455-A	5 x 10^-6	-	0.3	-	0.26 unit decrease	[0.14-0.38]	PRDM8-AS1, PRDM8	Response to cognitive-behavioural therapy in major depressive disorder	cognitive behavioural therapy	major depressive disorder	GCST008361	4:80185028
rs1458042-T	7 x 10^-6	-	0.3365	-	0.00497505 unit increase	[0.0028-0.0071]	PRDM8, PRDM8-AS1	Educational attainment	educational attainment	-	GCST90105038	4:80191733
rs13125101-A	2 x 10^-31	-	0.298049	-	-	-	PRDM8, FGF5	Hemoglobin concentration	hemoglobin measurement	-	GCST90002314	4:80253438
rs10857147-T	3 x 10^-20	-	0.290839	-	0.02255579 unit increase	[0.018-0.027]	PRDM8, FGF5	Hemoglobin	hemoglobin measurement	-	GCST90002384	4:80259918
rs11099098-T	2 x 10^-21	-	0.292735	-	0.023090918 unit increase	[0.018-0.028]	FGF5, PRDM8	Hematocrit	hematocrit	-	GCST90002383	4:80248758

Showing 1 to 5 of 372 entries

Studies306

Show entries

First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Replication sample number	Association count	Summary statistics

First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Replication sample number	Association count	Summary statistics

Sofer T	GCST004890	2017-09-04	Sci Rep	Genome-Wide Association Study of Blood Pressure…	Diastolic blood pressure	diastolic blood pressure	-	• 12278 Hispanic or Latin American	• 155786 European • 2764 Hispanic or Latin American • 22000 African American or Afro-Caribbean	1	Not available
Sofer T	GCST004891	2017-09-04	Sci Rep	Genome-Wide Association Study of Blood Pressure…	Mean arterial pressure	mean arterial pressure	-	• 12278 Hispanic or Latin American	• 155786 European • 22000 African American or Afro-Caribbean • 2764 Hispanic or Latin American	1	Not available
Sofer T	GCST004888	2017-09-04	Sci Rep	Genome-Wide Association Study of Blood Pressure…	Systolic blood pressure	systolic blood pressure	-	• 12278 Hispanic or Latin American	• 155786 European • 2764 Hispanic or Latin American • 22000 African American or Afro-Caribbean	1	Not available
Hillary RF	GCST90000469	2020-07-08	Genome Med	Multi-method genome- and epigenome-wide studies…	Fibroblast growth factor 5 levels	fibroblast growth factor 5 amount	-	• 982 European		1	FTP Download or API access
Kalnapenkis A	GCST90277792	2024-04-02	Sci Rep	Genetic determinants of plasma protein levels in…	FGF5 protein levels	fibroblast growth factor 5 amount	-	• 489 European		2	FTP Download

Showing 1 to 5 of 306 entries