GWAS Catalog

Gene: PRKACB

Gene information

Gene name

PRKACB

Description

protein kinase cAMP-activated catalytic subunit beta

Location

1:84078062-84238498

Cytogenetic region

Biotype

protein_coding

Available data:

Associations 8

Show entries

Variant and risk allele	P-value	P-value annotation	RAF	OR	Beta	CI	Mapped gene	Reported trait	Trait(s)	Background trait(s)	Study accession	Location

rs903263-?	1 x 10^-6	-	NR	1.27	-	[1.10-1.34]	PRKACB	Breast cancer (male)	male breast carcinoma	-	GCST001690	1:84156830
rs2811999-T	5 x 10^-6	-	NR	1.172	-	-	PRKACB	Dry eye disease	dry eye syndrome	-	GCST90444405	1:84153907
rs60726924-G	3 x 10^-6	-	NR	1.176	-	-	PRKACB	Dry eye disease	dry eye syndrome	-	GCST90444405	1:84200140
rs7524898-?	4 x 10^-9	-	NR	-	2.11067 unit decrease	[NR]	PRKACB	Femur bone mineral density x serum urate levels interaction	urate measurement	-	GCST012490	1:84167162
rs7524898-?	2 x 10^-8	(male)	NR	-	3.29753 unit decrease	[NR]	PRKACB	Femur bone mineral density x serum urate levels interaction	urate measurement	-	GCST012490	1:84167162

Showing 1 to 5 of 8 entries

Studies6

Show entries

First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Replication sample number	Association count	Summary statistics

First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Replication sample number	Association count	Summary statistics

Orr N	GCST001690	2012-09-23	Nat Genet	Genome-wide association study identifies a…	Breast cancer (male)	male breast carcinoma	-	• 3618 European	• 912 European	3	Not available
Hsu CC	GCST90444405	2024-05-01	Transl Vis Sci Technol	Predicting Risks of Dry Eye Disease Development…	Dry eye disease	dry eye syndrome	-	• 19725 East Asian		15	Not available
Sakaue S	GCST90018749	2021-09-30	Nat Genet	A cross-population atlas of genetic associations…	Platelet count	platelet count	-	• 148623 East Asian		136	FTP Download
Yao Y	GCST012490	2021-05-27	Endocrine	Evaluate the effects of serum urate level on…	Femur bone mineral density x serum urate levels interaction	urate measurement	-	• 4575 NR		653	Not available
Verma A	GCST90480651	2024-07-19	Science	Diversity and scale: Genetic architecture of…	platelet count (mean, inv-norm transformed)	platelet count	-	• 114731 African American or Afro-Caribbean • 55759 Hispanic or Latin American • 5948 East Asian • 407021 European		329	Not available

Showing 1 to 5 of 6 entries