Study information
Reported trait
Schizophrenia
Genotyping technology
Genome-wide genotyping array
Discovery sample description
40,675 European ancestry cases, 64,643 European ancestry controls
PubMed ID
First author
Pardiñas AF 
Full Summary Statistics
Not available
GxE
Trait(s)
Background Trait(s)
-
Platform [SNPs passing QC]
Illumina [8000000] (imputed)
Replication sample description
1,651 European ancestry cases, 4,111 cases, 142,717 European ancestry controls, 11,507 controls
15618 NR (Georgia, Russian Federation, Denmark, Italy, Serbia, The former Yugoslav Republic of Macedonia), 144368 European (Norway, Iceland)
Journal
Nat Genet
Publication date
2018-02-26
Terms/Licence
Title
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
Authors
Pardiñas AF , Holmans P, Pocklington AJ, Escott-Price V, Ripke S , Carrera N, Legge SE... , Bishop S, Cameron D , Hamshere ML, Han J, Hubbard L, Lynham A , Mantripragada K, Rees E, MacCabe JH , McCarroll SA, Baune BT, Breen G , Byrne EM , Dannlowski U, Eley TC , Hayward C , Martin NG, McIntosh AM, Plomin R, Porteous DJ, Wray NR , Caballero A, Geschwind DH, Huckins LM , Ruderfer DM, Santiago E , Sklar P, Stahl EA, Won H , Agerbo E , Als TD , Andreassen OA, Bækvad-Hansen M, Mortensen PB, Pedersen CB, Børglum AD, Bybjerg-Grauholm J , Djurovic S, Durmishi N, Pedersen MG, Golimbet V, Grove J , Hougaard DM , Mattheisen M, Molden E , Mors O, Nordentoft M, Pejovic-Milovancevic M, Sigurdsson E , Silagadze T, Hansen CS , Stefansson K, Stefansson H, Steinberg S, Tosato S , Werge T, GERAD1 Consortium:, CRESTAR Consortium:, Collier DA , Rujescu D, Kirov G, Owen MJ , O'Donovan MC , Walters JTR , GERAD1 Consortium, CRESTAR Consortium, GERAD1 Consortium, CRESTAR Consortium Show more >
, Holmans P, Pocklington AJ, Escott-Price V, Ripke S , Carrera N, Legge SE... , Bishop S, Cameron D , Hamshere ML, Han J, Hubbard L, Lynham A , Mantripragada K, Rees E, MacCabe JH , McCarroll SA, Baune BT, Breen G , Byrne EM , Dannlowski U, Eley TC , Hayward C , Martin NG, McIntosh AM, Plomin R, Porteous DJ, Wray NR , Caballero A, Geschwind DH, Huckins LM , Ruderfer DM, Santiago E , Sklar P, Stahl EA, Won H , Agerbo E , Als TD , Andreassen OA, Bækvad-Hansen M, Mortensen PB, Pedersen CB, Børglum AD, Bybjerg-Grauholm J , Djurovic S, Durmishi N, Pedersen MG, Golimbet V, Grove J , Hougaard DM , Mattheisen M, Molden E , Mors O, Nordentoft M, Pejovic-Milovancevic M, Sigurdsson E , Silagadze T, Hansen CS , Stefansson K, Stefansson H, Steinberg S, Tosato S , Werge T, GERAD1 Consortium:, CRESTAR Consortium:, Collier DA , Rujescu D, Kirov G, Owen MJ , O'Donovan MC , Walters JTR , GERAD1 Consortium, CRESTAR Consortium, GERAD1 Consortium, CRESTAR Consortium Show more >
Available data: