GWAS Catalog

Location

4:76480299

Cytogenetic region

Most severe consequence

Intron variant

Mapped gene(s)

Alleles

C/T(forward strand)

Minor allele

MAF

0.223116

GWAS Catalog data is currently mapped to Genome Assembly GRCh38.p14 and dbSNP Build156

Available data:

Show entries

Variant and risk allele	P-value	P-value annotation	RAF	OR	Beta	CI	Mapped gene	Reported trait	Trait(s)	Background trait(s)	Study accession	Location

rs28817415-T	3 x 10^-120	(discovery)	0.4037	-	0.0073 unit decrease	[0.0067-0.0079]	SHROOM3	Estimated glomerular filtration rate	glomerular filtration rate	-	GCST008058	4:76480299
rs28817415-T	2 x 10^-16	-	0.40	1.069	-	[1.0522-1.0861]	SHROOM3	Chronic kidney disease	chronic kidney disease	-	GCST008064	4:76480299
rs28817415-T	3 x 10^-22	-	0.3753	-	0.007 unit increase	[0.0056-0.0084]	SHROOM3	Blood urea nitrogen levels	blood urea nitrogen measurement	-	GCST008062	4:76480299
rs28817415-T	1 x 10^-103	(discovery)	0.44	-	0.0074 unit decrease	[0.0068-0.0080]	SHROOM3	Estimated glomerular filtration rate	glomerular filtration rate	-	GCST008059	4:76480299
rs28817415-T	2 x 10^-15	-	0.2172	-	0.0064 unit decrease	[0.0048-0.008]	SHROOM3	Estimated glomerular filtration rate	glomerular filtration rate	-	GCST008060	4:76480299

Showing 1 to 5 of 18 entries

Show entries

First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Replication sample number	Association count	Summary statistics

First author	Study accession	Pub. date	Journal	Title	Reported trait	Trait(s)	Background trait(s)	Discovery sample number	Association count	Summary statistics

Verma A	GCST90475744	2024-07-19	Science	Diversity and scale: Genetic architecture of…	Disorders of magnesium metabolism (PheCode 275.3)	metabolic disease	-	• 439149 European	3	FTP Download
Verma A	GCST90479680	2024-07-19	Science	Diversity and scale: Genetic architecture of…	magnesium (Mg, minimum, inv-norm transformed)	magnesium measurement	-	• 43617 African American or Afro-Caribbean • 18809 Hispanic or Latin American • 1638 East Asian • 145581 European	29	FTP Download
Wuttke M	GCST008060	2019-05-31	Nat Genet	A catalog of genetic loci associated with kidney…	Estimated glomerular filtration rate	glomerular filtration rate	-	• 165726 East Asian	45	Not available
Wuttke M	GCST008064	2019-05-31	Nat Genet	A catalog of genetic loci associated with kidney…	Chronic kidney disease	chronic kidney disease	-	• 625219 European, NR	47	FTP Download
Lee CJ	GCST90239628	2022-11-03	Commun Biol	Phenome-wide analysis of Taiwan Biobank reveals…	Creatinine levels	serum creatinine amount	-	• 76850 East Asian	58	Not available

Showing 1 to 5 of 18 entries

Variant: rs28817415