-3.1 | | ELL | 'micronodules adjacent to an hCG producing tumour' vs 'normal' in 'adult' | developmental stage, phenotype | Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents |
2.9 | | ELL | 'teratozoospermia' vs 'normospermic' | disease | Transcription profiling by array of human sperm from normospermic and teratozoospermic individuals |
2.7 | | ELL | 'human intestinal organoids derived from H9 stem cells' vs 'Undifferentiated H9 Stem Cells' | cell type | Transcriptional Profiling of human pluripotent stem cells and and derived tissues |
-2.7 | | ELL | 'colorectal carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-2.6 | | ELL | 'doxorubicin; 5 micomolar and T0901317; 5 micromolar' vs 'none' | compound | LXR mediated-signalling protects human hair follicles against doxorubicin-induced toxicity ex vivo |
-2.6 | | ELL | 'erythroleukemia; ZRSR2 shRNA' vs 'normal' | disease, genotype | RNA-seq of bone marrow from patients with myelodysplastic syndrome |
-2.5 | | ELL | 'non-triple-negative breast cancer; breast carcinoma' vs 'normal' | clinical information, disease | RNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples |
-2.5 | | ELL | 'West Nile Virus protein E domain DIII' at '6 hour' vs 'none' at '0 hour' | stimulus, time | Transcriptome analysis of human brain microvascular endothelial cells response to interactive DIII domain of protein E of WNV and interactive DIII domain of protein E of TBEV using RNA-seq |
2.4 | | ELL | 'sebaceous of Jadassohn nevus' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
-2.4 | | ELL | 'triple-negative breast cancer; breast carcinoma' vs 'normal' | clinical information, disease | RNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples |
2.3 | | ELL | 'induced into senescence; 5-aza-2-deoxycytidine' vs 'spontaneously immortal cells; control' | phenotype, treatment | Pathway Profiling of Replicative and Induced Senescence |
-2.3 | | ELL | 'HER2 Positive Breast Carcinoma; breast carcinoma' vs 'normal' | clinical information, disease | RNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples |
2.2 | | ELL | '24 hour' vs '0 hour' in 'MCF-10A' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
-2.2 | | ELL | 'ejaculatory azoospermia; Johnsen score count 3.2' vs 'normal; Johnsen score count 10' | disease, histology | Transcription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis |
-2.2 | | ELL | 'pancreatic adenocarcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
2 | | ELL | 'actinic keratosis' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
-2 | | ELL | '7 hour' vs '0 hour' in 'MDA-LM2' | cell line, time | Transcription profiling by high throughput sequencing in MDA-MB-231 and MDA-LM2 cell lines |
-2 | | ELL | 'ejaculatory azoospermia; Johnsen score count 2' vs 'normal; Johnsen score count 10' | disease, histology | Transcription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis |
1.9 | | ELL | 'squamous cell carcinoma' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
1.8 | | ELL | 'myeloid-related protein 8' vs 'control' on 'Affymetrix GeneChip Human Genome U133 Plus 2.0 [HG-U133_Plus_2]' | stimulus | Transcription profiling by array of human blood monocyte stimulated with various stimuli (control, MRP8, LPS, TNF, IL1) to study signalling pathways in phagocytic activation |
1.7 | | ELL | 'Digoxin; 400 nanomolar' vs 'DMSO' | compound | Expression profiling of Jurkat cells infected with HIV-1 and treated with digoxin or DMSO |
1.7 | | ELL | 'GLV-1h153' at '24 hour' vs 'control' | infect, time | Expression data from human pancreatic cells PANC-1 infected with oncolytic vaccinia virus GLV-1h153 |
1.7 | | ELL | 'Francisella tularensis novicida' vs 'uninfected' | infect | Transcription profiling by array of human peripheral blood mononuclear cells infected with Francisella tularensis |
-1.6 | | ELL | 'ejaculatory azoospermia; Johnsen score count 5' vs 'normal; Johnsen score count 10' | disease, histology | Transcription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis |
-1.6 | | ELL | 'breast carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-1.5 | | ELL | 'cisplatin; 100 micromolar' vs 'none' in 'TMEM45A knockdown by siRNA' | RNA interference, compound | RNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin |
-1.5 | | ELL | '7 hour' vs '0 hour' in 'MDA-MB-231' | cell line, time | Transcription profiling by high throughput sequencing in MDA-MB-231 and MDA-LM2 cell lines |
-1.5 | | ELL | 'blood alcohol content 0.02%declining' vs 'control' in 'time point 5' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
1.5 | | ELL | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '54 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
1.5 | | ELL | 'EGR2-E356K' vs 'wild type genotype' | genotype | RNA-sequencing of human B cells to investigate chronic lymphocytic leukemia mutations observed in hematopoietic multipotent progenitor fractions |
-1.5 | | ELL | 'Zaire ebolavirus lacking the mucin domain of GP' vs 'mock' at '8 hour' | infect, time | Human U937 cell transcriptome response to Zaire Ebola virus wild-type in the delta-VP30 background and delta-mucin virus |
-1.5 | | ELL | 'metastatic melanoma; responder' vs 'normal; not applicable' | disease, response to treatment | Bulk RNA-seq validation experiment comparing blood from healthy donors and two groups of metastatic melanoma patients: responders and non-responders to anti-PD-1 immunotherapy |
-1.4 | | ELL | 'doxorubicin; 5 micromolar' vs 'none' | compound | LXR mediated-signalling protects human hair follicles against doxorubicin-induced toxicity ex vivo |
1.4 | | ELL | 'pBABE-puro-H-RasG12V; senescent' vs 'control; proliferative' | genotype, phenotype | Transcription profiling by high throughput sequencing of proliferative and Ras-induced senescent human primary fibroblasts |
1.4 | | ELL | 'EX00000246; stimulated with interferon gamma and lipopolysaccharide' vs 'none' at '24 hour' | compound, time, treatment | GPBAR1 agonism has a broad impact on blocking macrophage activation |
-1.4 | | ELL | 'non-small cell lung carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-1.3 | | ELL | 'SOX2 overexpression' vs 'wild type' in 'U-2982' | cell line, phenotype | RNA-seq of human glioblastoma cell lines with overexpression of SOX2, SFRP2 |
1.3 | | ELL | 'mucosal invariant T cell' vs peripheral blood mononuclear cell' in 'normal; blood' | cell type, disease, organism part | RNA-seq expression profiling of humain MAIT cells in blood and liver as compared to mainstream TCD4+ and TCD8+ cells. |
1.3 | | ELL | 'heat-killed Escherichia coli' vs 'none' in 'ulcerative colitis' | disease, stimulus | Transcription profiling by array of primary human macrophages cultured from patients with ulcerative colitis or healthy individuals with or without stimulation by heat-killed E. coli |
1.3 | | ELL | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '60 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
1.3 | | ELL | 'ulcerative colitis, inflammation' vs 'normal, normal tissue' in 'colon' | disease, organism part, sampling site | RNA-seq of biopsies, crypts and organoids of inflamed and non-inflamed biopsies of ulcerative colitis patients |
1.3 | | ELL | 'Human betacoronavirus 2c England-Qatar/2012; 24 hour' vs 'mock; 18 hour' | infect, time | Transcription profiling of human bronchial epithelial cell line Calu-3 2B4 infected with Human Coronavirus MERS-CoV-London |
1.3 | | ELL | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '72 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
-1.3 | | ELL | 'Ataxia-telangiectasia' vs 'normal' | disease | Ataxia-telangiectasia cerebellar cortex expression |
-1.3 | | ELL | 'ejaculatory azoospermia; Johnsen score count 8' vs 'normal; Johnsen score count 10' | disease, histology | Transcription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis |
-1.3 | | ELL | '6 hour' vs '0 hour' in 'cytomegalovirus infection' | time | Transcriptome modulation analysis of cytomegalovirus-infected immature monocyte-derived dendritic cells |
1.3 | | ELL | 'Mycobacterium tuberculosis' vs 'none' in 'infant' | developmental stage, infect | Multifaceted dysfunction of infant airway macrophages in response to Mycobacterium tuberculosis |
-1.3 | | ELL | 'trabectedin; 10 nanomolar' vs 'none' | compound | Whole transcriptome profiling by microarray of monocytes stimulated with LPS and treated with trabectedin, lurbinectedin or doxorubicin |
-1.2 | | ELL | 'expression of estrogen receptor beta fused to C terminus tandem affinity purification tag' vs 'expression of estrogen receptor alpha fused to C terminus tandem affinity purification tag' | genotype | The nuclear receptor ERbeta engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Part 4 |
-1.2 | | ELL | 'DMSO' in 'stimulated with interferon gamma and lipopolysaccharide' vs 'none' at '6 hour' | compound, time, treatment | GPBAR1 agonism has a broad impact on blocking macrophage activation |
1.2 | | ELL | 'malignant mesothelioma; wild type' vs 'normal; wild type' | disease, genotype | Expression profile of shERK1, shERK2, shERK5 and shControl HMESO cells |
1.2 | | ELL | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '48 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
-1.2 | | ELL | 'shRNA22' vs 'control shRNA' | RNA interference | Transcriptional effect of an off-target shRNA targeting nucleostemin in human glioblastoma-derived cancer stem cells |
-1.2 | | ELL | 'glioblastoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
1.2 | | ELL | "after autologous stem cell transplantation" vs "before autologous stem cell transplantation" | time | RNA-seq of human multiple myeloma patients myeloid-derived suppressor cells (M-MDSC) |
1.2 | | ELL | 'arsenite' vs 'control' | compound | Transcription profiling by high throughput sequencing of 293S cells treated with arsenite |
1.1 | | ELL | 'inflammatory bowel disease' vs 'normal' in 'none; blood; normal tissue' at '0 week' | block, cohort, disease, organism part, sampling site, time | A functional genomics predictive network model identifies regulators of inflammatory bowel disease: Microarray Analysis of Human Blood and Intestinal Biopsy Samples from a Phase 2b, Double-blind, Placebo-controlled Study of Ustekinumab in Crohn's Disease |
-1.1 | | ELL | 'EX00000246; stimulated with interferon gamma and lipopolysaccharide' vs 'none' at '6 hour' | compound, time, treatment | GPBAR1 agonism has a broad impact on blocking macrophage activation |
-1.1 | | ELL | 'cisplatin; 100 micromolar' vs 'none' in 'scrambled siRNA' | RNA interference, compound | RNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin |
1.1 | | ELL | 'Candida albicans' vs 'none' at '24 hour' | infect, time | Gene expression microarray of oral epithelial cells infected with Candida albicans |
-1.1 | | ELL | 'ejaculatory azoospermia; Johnsen score count 7' vs 'normal; Johnsen score count 10' | disease, histology | Transcription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis |
1.1 | | ELL | 'Staphylococcus aureus strain SK2' vs 'none' | infect | Transcription profiling of human primary bone cells exposed to Staphylococcus aureus |
-1 | | ELL | 'progenitor cell of endocrine pancreas' vs 'definitive endoderm cell' in 'GATA6 R456C/+; Patient A" | cell line, cell type, genotype, individual | RNA-seq of definitive endoderm and pancreatic progenitor cells derived in vitro from human pluripotent stem cells in order to study the role of transcription factor GATA6 in human pancreas development |
1 | | ELL | 'POLR2D knock-down' vs 'mock' | RNA interference | RNA-seq analysis of vorinostat-resistant HCT116 cells following gene knockdown of potential vorinostat-resistance candidate genes |
1 | | ELL | 'Listeria monocytogenes EGD-e' vs 'none' | infect | Transcription profiling by high throughput sequencing of LoVo cells infected with Listeria for 24 hr compared to uninfected cells |
1 | | ELL | 'systemic-onset juvenile idiopathic arthritis; placebo, Prednisone, non-steroidal anti-inflammatory drug, methotrexate' vs 'normal; none' | disease, treatment | Gene expression data of whole blood of systemic juvenile idiopathic arthritis (SJIA) patients treated with canakinumab or placebo and age matched healthy controls |
-1 | | ELL | 'heat shock' vs 'untreated' | growth condition | RNA-seq analysis of U2OS cells exposed to heat stress |
1 | | ELL | 'HFF1; cocultured with epithelial MDAMB231 cells' vs 'HFF1; normal' | cell line, growth condition | System-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity |
1 | | ELL | 'lipid A; 200 nanogram per milliliter' vs 'none' in 'none' | compound, stimulus | RNA-seq of PBMC derived macrophages derived from healthy donors in response to lipid A or TNF alpha (Dataset_170630_SysmedIBD_RNA_HEngland) |
-1 | | ELL | '6 hour' vs '0 hour' in 'MCF-10A-H1047R' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
1 | | ELL | 'JQ1 (1 micromolar) and THZ1 (35 nanomolar)' vs 'none' | compound | RNA-seq of IMR-5/75 neuroblastoma cell line treated with JQ1, THZ1 or combination against untreated controls |
-1 | | ELL | 'estrogen receptor alpha shRNA' vs 'scrambled shRNA' | RNA interference | RNA-seq of the human breast cancer ERα-suppressed MCF-7(MCF-7/SP10+) cells and of their internal control MCF-7 (MCF-7/C) cells |
1 | | ELL | 'induced into senescence; adriamycin' vs 'spontaneously immortal cells; control' | phenotype, treatment | Pathway Profiling of Replicative and Induced Senescence |
1 | | ELL | '154; 1 micromolar' vs 'DMSO' | compound | Development of a small molecule for treatment of castration resistant prostate cancer via androgen receptor and IL6/STAT3 pathways |
1 | | ELL | 'sepsis' vs 'normal' in 'whole blood' | cell type, disease, treatment | Next generation sequencing of human immune cell subsets across diseases |
1 | | ELL | 'herpes simplex virus G207' vs 'none' | infect | Transcription profiling by array of human malignant peripheral nerve sheath tumor cells after infection with herpes simplex virus G207 |
1 | | ELL | 'heat-killed Escherichia coli' vs 'none' in 'normal' | disease, stimulus | Transcription profiling by array of primary human macrophages cultured from patients with ulcerative colitis or healthy individuals with or without stimulation by heat-killed E. coli |
-1 | | ELL | 'differentiated macrophage' at '168 hour' vs '0 hour' | time | Transcription profiling of human monocytes to macrophage differentiation |
-1 | | ELL | 'small cell lung carcinoma' vs 'normal' | disease | RNA-seq of primary tumors from 79 small cell lung cancer patients and 7 normal lung tissue |
