ENSG00000197157 (SND1)

homo sapiens

staphylococcal nuclease and tudor domain containing 1

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Homo sapiens
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Showing 8 experiments:
image/svg+xml human body features 2009-05-27 Sjef text : Kevin (tsaitgaist) REDON http://commons.wikimedia.org/wiki/File:Human_body_features.svg cerebral cortex pleura brain heart breast thyroid gland adrenal gland lymph node bone marrow adipose tissue skeletal muscle leukocyte frontal cortex temporal lobe prefrontal cortex pituitary gland atrial appendage aorta coronary artery gastroesophageal junction left ventricle hippocampus hippocampus caecum ileum rectum nose tongue left atrium pulmonary valve mitral valve penis vas deferens seminal vesicle testis epididymis eye nasal septum oral cavity tonsil nasal pharynx lung spinal cord amygdala trachea throat bronchus tricuspid valve diaphragm liver stomach spleen duodenum gall bladder pancreas colon small intestine appendix smooth muscle urinary bladder prostate gland nerve cerebellum cerebellar hemisphere kidney renal cortex bone cartilage esophagus salivary gland parotid gland submandibular gland skin
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.3894 × 10-3-3.3
SND1'lurbinectedin; 10 nanomolar' vs 'none'compoundWhole transcriptome profiling by microarray of monocytes stimulated with LPS and treated with trabectedin, lurbinectedin or doxorubicin
Adjusted p-valueLog2-fold change
2.0255 × 10-2-2.9
SND1'trabectedin; 10 nanomolar' vs 'none'compoundWhole transcriptome profiling by microarray of monocytes stimulated with LPS and treated with trabectedin, lurbinectedin or doxorubicin
Adjusted p-valueLog2-fold change
4.8257 × 10-1232.2
SND1'CD3/CD28 beads' vs 'none' in 'none'stimulus, xenograftRNA-Seq of T cells sorted from human PBMCs, or from T cells stimulated with CD3/CD28 beads for 4 days, or from the spleen of NSG or NSG-HLA-A2/HHD mice, 7 days after transplantation with human PBMCs
Adjusted p-valueLog2-fold change
9.0421 × 10-7-2.2
SND1'cisplatin' at '24 hour' vs 'none' at '0 hour'compound, timeTranscription profiling by array of human U87 cells treated with cytotoxic anticancer drug cisplatin or a ruthenium-based compound for 6 or 24 hours compared to untreated controls
Adjusted p-valueLog2-fold change
2.8795 × 10-13-1.9
SND1'P-bodies (cytosolic RNP granules)' vs 'pre-sorted fraction'fractionRNA-Seq of purified P-bodies from HEK293 cells
Adjusted p-valueLog2-fold change
1.1393 × 10-2051.5
SND1'injected in NSG mouse' vs 'none' in 'none'stimulus, xenograftRNA-Seq of T cells sorted from human PBMCs, or from T cells stimulated with CD3/CD28 beads for 4 days, or from the spleen of NSG or NSG-HLA-A2/HHD mice, 7 days after transplantation with human PBMCs
Adjusted p-valueLog2-fold change
5.4939 × 10-1731.5
SND1'injected in NSG-HLA-A2/HHD mouse' vs 'none' in 'none'stimulus, xenograftRNA-Seq of T cells sorted from human PBMCs, or from T cells stimulated with CD3/CD28 beads for 4 days, or from the spleen of NSG or NSG-HLA-A2/HHD mice, 7 days after transplantation with human PBMCs
Adjusted p-valueLog2-fold change
1.5803 × 10-41.5
SND1'pancreatic ductal adenocarcinoma, neoplasm' vs 'normal; normal tissue' in 'pancreas'disease, organism partTranscription profiling by array of normal pancreas, primary pancreatic ductal adenocarcinoma (PDAC), normal liver, and pancreatic liver metastases using the Affymetrix HG-U133A array
Adjusted p-valueLog2-fold change
5.1877 × 10-4-1.5
SND1'pancreatic cancer' vs 'normal' on 'Affymetrix GeneChip Human Genome HG-U133A [HG-U133A]' on 'Affymetrix GeneChip Human Genome HG-U133A [HG-U133A]'diseaseMolecular analysis of precursor lesions in familial pancreatic cancer
Adjusted p-valueLog2-fold change
8.6759 × 10-41.5
SND1'astrocytoma' vs 'normal'diseaseTranscription profiling of human grade II astrocytic tumor (astrocytomas) vs grade IV tumors (glioblastoma)
Adjusted p-valueLog2-fold change
3.0185 × 10-41.4
SND1'tumor' vs 'paratumoral tissue'clinical informationTranscriptomic characterization of Hepatocellular Carcinoma with CTNNB1 mutation
Adjusted p-valueLog2-fold change
6.2899 × 10-4-1.4
SND1'Ataxia-telangiectasia' vs 'normal'diseaseAtaxia-telangiectasia cerebellar cortex expression
Adjusted p-valueLog2-fold change
8.5379 × 10-4-1.4
SND1"after autologous stem cell transplantation" vs "before autologous stem cell transplantation"timeRNA-seq of human multiple myeloma patients myeloid-derived suppressor cells (M-MDSC)
Adjusted p-valueLog2-fold change
1.7727 × 10-221.3
SND1'Human gammaherpesvirus 4' at '14 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
6.1122 × 10-41.3
SND1'T-helper 1 polarising' at '1 day' vs 'no stimulus'cell type, sampling time point, stimulusTranscription profiling by array of human CD4+T-cells, Th1/Th2 polarized time-series and primary memory subsets
Adjusted p-valueLog2-fold change
2.4963 × 10-391.2
SND1'Human gammaherpesvirus 4' at '2 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
1.1629 × 10-351.2
SND1'Human gammaherpesvirus 4' at '3 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
3.122 × 10-61.2
SND1'MOLT-4; acute lymphoblastic leukemia; P04' vs 'MOLT-4; acute lymphoblastic leukemia; P0'cell line, disease, passageMicroarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI)
Adjusted p-valueLog2-fold change
3.2759 × 10-61.2
SND1'plasmablast' vs 'memory B cell'cell typeTranscription profiling by array of human activated B cells, plasmablasts and plasma cells compared to memory B cells
Adjusted p-valueLog2-fold change
3.433 × 10-5-1.2
SND1'Zaire ebolavirus lacking the mucin domain of GP' vs 'mock' at '8 hour'infect, timeHuman U937 cell transcriptome response to Zaire Ebola virus wild-type in the delta-”VP30 background and delta-mucin virus
Adjusted p-valueLog2-fold change
8.145 × 10-51.2
ENSG00000197157'primary tumor' vs 'adjacent non-tumor colon' in 'colorectal cancer'disease, sampling siteRNA-seq of colorectal cancer primary tumor and adjacent colon tissue
Adjusted p-valueLog2-fold change
8.4739 × 10-3-1.2
SND1'Influenza A virus' vs 'mock' in 'PBS'compound, infectProfiling of human bronchial epithelial BEAS-2B infected with influenza A and treated with succinate to study the anti-influenza activity of succinate
Adjusted p-valueLog2-fold change
1.9201 × 10-2-1.2
SND1'PanIN lesion' vs 'normal' on 'Affymetrix GeneChip Human Genome HG-U133A [HG-U133A]' on 'Affymetrix GeneChip Human Genome HG-U133A [HG-U133A]'diseaseMolecular analysis of precursor lesions in familial pancreatic cancer
Adjusted p-valueLog2-fold change
3.4989 × 10-201.1
SND1'Human gammaherpesvirus 4' at '4 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
1.4667 × 10-8-1.1
SND1'tumor necrosis factor alpha' vs 'none' in 'brain microvascular endothelial cell; monoculture'cell type, growth condition, stimulusReactive astrocytes transduce blood-brain barrier inflammation through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin
Adjusted p-valueLog2-fold change
7.0716 × 10-8-1.1
SND1'CRISPR-Cas9 induced GNRH1 reporter; 27 day' vs 'wild type genotype; 20 day'genotype, stimulus, timeRNA-Seq of GNRH1 neurons differentiated from human pluripotent stem cells
Adjusted p-valueLog2-fold change
1.2353 × 10-41.1
SND1'medulloblastoma, large-cell' vs 'normal'diseasePediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes
Adjusted p-valueLog2-fold change
8.9755 × 10-41.1
SND1'T-helper 2 polarising' at '1 day' vs 'no stimulus'cell type, sampling time point, stimulusTranscription profiling by array of human CD4+T-cells, Th1/Th2 polarized time-series and primary memory subsets
Adjusted p-valueLog2-fold change
1.3339 × 10-31.1
SND1'psoriasis' vs 'normal' in 'Ovation RNA Amplification V2 kit'disease, protocolDominant Th1 and Minimal Th17 Skewing in Discoid Lupus Revealed by Transcriptomic Comparison with Psoriasis
Adjusted p-valueLog2-fold change
7.2126 × 10-31.1
SND1'24 hours with hMSC Adipogenic Differentiation Bullet Kit' vs 'none' in 'monosome'fraction, protocolRNA-seq of total RNA from human adipose tissue stem cells induced to adipogenesis and osteogenesis for 24 hours
Adjusted p-valueLog2-fold change
8.6537 × 10-87-1
SND1'doxycycline; 0.5 microgram per milliliter; Day 4 post Neurogenin induction' vs 'control'compound, treatmentRapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq)
Adjusted p-valueLog2-fold change
7.1118 × 10-121
SND1'JQ1 (1 micromolar) and THZ1 (35 nanomolar)' vs 'none'compoundRNA-seq of IMR-5/75 neuroblastoma cell line treated with JQ1, THZ1 or combination against untreated controls
Adjusted p-valueLog2-fold change
7.9166 × 10-111
SND1'Human gammaherpesvirus 4' at '5 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
2.1864 × 10-9-1
SND1'Digoxin; 400 nanomolar' vs 'DMSO'compoundExpression profiling of Jurkat cells infected with HIV-1 and treated with digoxin or DMSO
Adjusted p-valueLog2-fold change
2.8616 × 10-61
SND1'AQM' vs 'normal' on 'Affymetrix HG-U133A'diseaseTranscription profiling by array of 12 human muscle diseases
Adjusted p-valueLog2-fold change
1.6596 × 10-51
SND1'activated B cell' vs 'memory B cell'cell typeTranscription profiling by array of human activated B cells, plasmablasts and plasma cells compared to memory B cells
Adjusted p-valueLog2-fold change
2.3696 × 10-51
SND1'plasma cell' vs 'memory B cell'cell typeTranscription profiling by array of human activated B cells, plasmablasts and plasma cells compared to memory B cells
Adjusted p-valueLog2-fold change
4.0134 × 10-51
SND1'Human gammaherpesvirus 4' at '8 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
8.0989 × 10-5-1
SND1'differentiated; hAKPC-P' vs 'undifferentiated; hAKPC-P'cell type, phenotypeDifferentiation of human amniotic fluid kidney progenitor cells into podocytes and comparison with human conditionally immortalized podocytes
Adjusted p-valueLog2-fold change
8.7661 × 10-5-1
SND1'lymphangiogenic and very metastatic' vs 'parental pool'phenotypeExpression data from melanoma subpopulations
Adjusted p-valueLog2-fold change
8.2848 × 10-41
SND1'group 3 medulloblastoma' vs 'normal'diseaseGene expression profile of pediatric and adult brain tumor types and normal brain
Adjusted p-valueLog2-fold change
8.9545 × 10-41
SND1'lung cancer' vs 'normal' in 'lung; Formalin-fixed paraffin-embedded tissue'disease, organism part, protocolTranscription profiling by array of formalin-fixed paraffin-embedded or fresh frozen human tumor samples
Adjusted p-valueLog2-fold change
2.5686 × 10-3-1
SND1'type I diabetes mellitus' vs 'normal'disease stagingTranscription profiling human whole blood from children with pre-type1diabetes
Adjusted p-valueLog2-fold change
9.3111 × 10-3-1
SND1'diabetes mellitus' vs 'normal'diseaseAn integrative analysis of skeletal muscle insulin resistance
Adjusted p-valueLog2-fold change
1.0559 × 10-21
SND1'TGFbeta3' vs 'control' at '3 day'growth condition, timeTranscription profiling by array of human bone marrow mesenchymal stem cells after treatment with BMP2 or TGFbeta-3
Adjusted p-valueLog2-fold change
2.6768 × 10-21
SND1'PKA RI-alpha over expression' vs 'wild type'genotypeTranscription profiling by array of human ovarian cancer cells over-expressing PKA regulatory subunits
Adjusted p-valueLog2-fold change
3.252 × 10-21
SND1'liver tumor' vs 'adjacent non-tumor tissue'clinical informationTranscriptome sequencing of human hepatocellular carcinoma
Adjusted p-valueLog2-fold change
3.7248 × 10-30.6
ENSG00000197157'intravascular lymphoma' vs 'diffuse large B-cell lymphoma'disease113 DLBCL SWATH maps by PCT-SWATH
Adjusted p-valueLog2-fold change
1.1123 × 10-2-0.5
ENSG00000197157'tumor' vs 'normal tissue' in 'frozen specimen'sampling site, specimen with known storage stateComparison of FFPE and fresh frozen prostate tissues using PCT SWATH