ENSMUSG00000009734 (Pou6f2)

mus musculus

POU domain, class 6, transcription factor 2

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Mus musculus
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Showing 25 experiments:
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Created with Highcharts 6.2.0arcuate nucleus of hypothalamusbronchuscaudal brain neural epitheliumcerebellumcortexdorsal control neural epitheliumfloor platehippocampal formationhypothalamuskidneylateral prominence neural epitheliumlungmaxillary archmedial prefrontal cortexmuscle tissueolfactory bulbolfactory pitskeletal muscle tissuestriatumtestistracheazone of skin
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9 in 3 strains - DBA/2J
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Mammalian Kaessmann
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Developing gut
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9 in 3 strains - CD1
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9 in 3 strains - C57BL/6
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6
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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Mernberger et al 2019 - Organism Part
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Vertebrates
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2
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - C57BL/6J
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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3 Soumillon et al
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14 - embryonic day 8.5
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14 - embryonic day 10.5
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4 Bonthuis et al - Idaho derived wild …
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Duda et al., 2018 - organism part - …
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Duda et al., 2018 - organism part - …
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Proteomics
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Transcriptomics
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-1
-6.6
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4.5
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.3283 × 10-4-6.6
Pou6f2'neural stem cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
7.3217 × 10-4-4.9
Pou6f2'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
4.1738 × 10-294.5
Pou6f2'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
2.7521 × 10-53.6
Pou6f2'oculomotor nucleus motor neurons' vs 'lumbar motor neurons'cell typeComparison of gene expression in motor pools with differential vulnerability in ALS
Adjusted p-valueLog2-fold change
5.8894 × 10-3-2.7
Pou6f2'H-Ras expression' vs 'wild type'phenotypeRNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.
Adjusted p-valueLog2-fold change
2.5615 × 10-22.6
Pou6f2'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.547 × 10-32.3
Pou6f2'neuron' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
8.7641 × 10-51.9
Pou6f2'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
2.2488 × 10-2-1.9
Pou6f2'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
9.667 × 10-51.7
Pou6f2'Sall4 -/-' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells in response to changes in Sall4
Adjusted p-valueLog2-fold change
1.042 × 10-8-1.6
Pou6f2'Nolz1-/-' vs 'wild type genotype'genotypeTranscriptomic (RNA-seq) analysis of wild-type and Nolz1-/- (Zfp503) mutant striatal tissue reveals altered expression of several genes involved in striatal projection neuron specification.
Adjusted p-valueLog2-fold change
4.6268 × 10-31.6
Pou6f2'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
6.9731 × 10-31.6
Pou6f2'Aire knockout' vs 'wild type' in 'cTEC'genotype, phenotypeTranscription profiling by high throughput sequencing of primary cTEC, mTEClo, and mTEChi harvested from wild type and Aire-deficient mice
Adjusted p-valueLog2-fold change
4.8115 × 10-41.4
Pou6f2'Dicer knock out' vs 'wild type'genotypeTranscription profiling by array of mouse Dicer-deficient ooctyes
Adjusted p-valueLog2-fold change
4.9655 × 10-31.4
Pou6f2'Ngn3-expressing cell' vs 'Ngn3-null cell'cell typeTranscriptional profiling of Ngn3-dependent pancreatic endocrine differentiation at E15.5
Adjusted p-valueLog2-fold change
1.4106 × 10-21.3
Pou6f2'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
5.3424 × 10-4-1.2
Pou6f2'pabpn1l -/-' vs 'wild type genotype' in 'zygote'genotype, organism partRNA-seq of oocytes and zygotes from pabpn1l ko and wt female mice
Adjusted p-valueLog2-fold change
3.7956 × 10-2-1.2
Pou6f2'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1'cell type, growth condition, phenotypeTranscription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture
Adjusted p-valueLog2-fold change
2.5955 × 10-81
Pou6f2'CAG driven deletion of miR.16b~25' vs 'wild type phenotype'phenotypeEffect of miR-106b~25 in mouse spermatogenesis and male fertility
Adjusted p-valueLog2-fold change
1.7182 × 10-6-1
Pou6f2'NrlGFP positive' vs 'NrlGFP negative'phenotypeTranscription profiling by array of photoreceptor precursor cells selected via cell surface antigen expression.