Wolfram syndrome
Wolfram syndrome (WS) also known as DIDMOAD, is a neurodegenerative disorder characterized by type I diabetes mellitus (DM), diabetes insipidus (DI), sensorineural deafness (D), bilateral optical atrophy (OA) and neurological signs. Other related problems are urinary tract atony, ataxia, peripheral neuropathy, psychiatric disorders and/or seizures. 2 types of WS may be distinguished: type 1 and type 2 (WS1 and WS2).
Exact Synonyms
diabetes insipidus, diabetes mellitus, optic atrophy, and deafness syndrome
diabetes insipidus-diabetes mellitus-optic atrophy-deafness syndrome
diabetes mellitus and insipidus with optic atrophy and deafness
DIDMOAD syndrome
DIDMOAD
WFS
Wolfram syndrome
class Information
curated content resource
https://search.clinicalgenome.org/kb/conditions/MONDO:0018105
has exact match
has_dbxref
- Wolfram syndromedoid
- GARD:7898
- icd11.foundation:151381747
- ICD9:250.80
- MEDGEN:21923
- MESH:D014929
- NANDO:1200757
- Wolfram Syndromencit
- Orphanet:3463
- SCTID:70694009
- UMLS:C0043207