EMD-11617
Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 2-up conformation
EMD-11617
Single-particle2.94 Å
Deposition: 16/08/2020Map released: 21/10/2020
Last modified: 18/11/2020
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
synthetic construct
Sample: SARS-CoV-2 spike glycoprotein in 1-up conformation bound by 3 neutralising Sybodies (Sb23)
Fitted models: 7a29
Deposition Authors: Hallberg BM, Das H
Sample: SARS-CoV-2 spike glycoprotein in 1-up conformation bound by 3 neutralising Sybodies (Sb23)
Fitted models: 7a29
Deposition Authors: Hallberg BM, Das H
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.
Custodio TF 
,
Das H ,
Sheward DJ ,
Hanke L ,
Pazicky S ,
Pieprzyk J,
Sorgenfrei M,
Schroer MA ,
Gruzinov AY ,
Jeffries CM ,
Graewert MA ,
Svergun DI,
Dobrev N ,
Remans K ,
Seeger MA ,
McInerney GM ,
Murrell B ,
Hallberg BM ,
Low C
(2020) Nat Commun , 11 , 5588 - 5588
,
Das H ,
Sheward DJ ,
Hanke L ,
Pazicky S ,
Pieprzyk J,
Sorgenfrei M,
Schroer MA ,
Gruzinov AY ,
Jeffries CM ,
Graewert MA ,
Svergun DI,
Dobrev N ,
Remans K ,
Seeger MA ,
McInerney GM ,
Murrell B ,
Hallberg BM ,
Low C
(2020) Nat Commun , 11 , 5588 - 5588