EMD-12286
Cryo-EM structure of the ternary complex between Netrin-1, Neogenin and Repulsive Guidance Molecule B
EMD-12286
Single-particle5.98 Å
Deposition: 01/02/2021Map released: 31/03/2021
Last modified: 28/04/2021
Sample Organism:
Homo sapiens,
Mus musculus
Sample: Cryo-EM structure of the ternary Netrin 1-Neogenin 1-Repulsive Guidance Molecule B complex
Fitted models: 7ndg
Deposition Authors: Robinson RA, Griffiths SC, van de Haar LL, Malinauskas T, van Battum EY, Zelina P, Schwab RA, Karia D, Malinauskaite L, Brignani S, van den Munkhof M, Dudukcu O, De Ruiter AA, Van den Heuvel DMA, Bishop B, Elegheert J, Aricescu AR, Pasterkamp RJ, Siebold C
Sample: Cryo-EM structure of the ternary Netrin 1-Neogenin 1-Repulsive Guidance Molecule B complex
Fitted models: 7ndg
Deposition Authors: Robinson RA, Griffiths SC, van de Haar LL, Malinauskas T, van Battum EY, Zelina P, Schwab RA, Karia D, Malinauskaite L, Brignani S, van den Munkhof M, Dudukcu O, De Ruiter AA, Van den Heuvel DMA, Bishop B, Elegheert J, Aricescu AR, Pasterkamp RJ, Siebold C
Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling.
Robinson RA 
,
Griffiths SC,
van de Haar LL ,
Malinauskas T,
van Battum EY,
Zelina P,
Schwab RA,
Karia D,
Malinauskaite L ,
Brignani S,
van den Munkhof MH,
Dudukcu O ,
De Ruiter AA,
Van den Heuvel DMA,
Bishop B,
Elegheert J ,
Aricescu AR ,
Pasterkamp RJ,
Siebold C
(2021) Cell , 184 , 2103
,
Griffiths SC,
van de Haar LL ,
Malinauskas T,
van Battum EY,
Zelina P,
Schwab RA,
Karia D,
Malinauskaite L ,
Brignani S,
van den Munkhof MH,
Dudukcu O ,
De Ruiter AA,
Van den Heuvel DMA,
Bishop B,
Elegheert J ,
Aricescu AR ,
Pasterkamp RJ,
Siebold C
(2021) Cell , 184 , 2103