EMD-13605

Single-particle
3.03 Å
EMD-13605
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Deposition: 20/09/2021
Map released: 17/08/2022
Last modified: 17/07/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-13605
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7pqu summary report (pdf.gz) Map and 7pqu FULL report (pdf.gz)
EMICSS annotations (xml)

Ligand-bound human Kv3.1 cryo-EM structure (Lu AG00563)

EMD-13605

Single-particle
3.03 Å
EMD-13605
3D View Gallery
Deposition: 20/09/2021
Map released: 17/08/2022
Last modified: 17/07/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Detergent solubilized tetramer of human Kv3.1 potassium ion channel in complex with Lu AG00563
Fitted models: 7pqu

Deposition Authors: Botte M, Huber S, Bucher D , Klint JK, Rodriguez D , Tagmose L, Chami M , Cheng R, Hennig M , Abdul Rhaman W
Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators.
Botte M, Huber S, Bucher D , Klint JK, Rodriguez D , Tagmose L, Chami M , Cheng R, Hennig M , Abdul Rahman W
(2022) Pnas Nexus , 1 , pgac083 - pgac083
PUBMED: 36741467
DOI: doi:10.1093/pnasnexus/pgac083
ISSN: 2752-6542