EMD-16189

Helical reconstruction
2.3 Å
EMD-16189
3D View Gallery
Deposition: 18/01/2023
Map released: 22/02/2023
Last modified: 24/07/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-16189
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8bqw summary report (pdf.gz) Map and 8bqw FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of alpha-synuclein filaments doublet from Juvenile-onset synucleinopathy

EMD-16189

Helical reconstruction
2.3 Å
EMD-16189
3D View Gallery
Deposition: 18/01/2023
Map released: 22/02/2023
Last modified: 24/07/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Alpha-synuclein doublet filament extracted from the human brain with JOS
Fitted models: 8bqw

Deposition Authors: Yang Y , Garringer JH, Shi Y, Zhang XJ, Kotecha A, Bacioglu M, Koto A, Takao M, Spillantini GM, Ghetti B, Vidal R , Murzin GA, Scheres HWS, Goedert M, Ghetti B, Hasegawa M, Lashley T, Scheres HWS, Goedert M
New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Yang Y , Garringer HJ , Shi Y, Lovestam S, Peak-Chew S, Zhang X, Kotecha A, Bacioglu M, Koto A, Takao M, Spillantini MG, Ghetti B, Vidal R , Murzin AG, Scheres SHW, Goedert M
(2023) Acta Neuropathol , 145 , 561 - 572
PUBMED: 36847833
DOI: doi:10.1007/s00401-023-02550-8
ISSN: 1432-0533