EMD-16473

Single-particle
4.41 Å
EMD-16473
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Deposition: 19/01/2023
Map released: 10/01/2024
Last modified: 21/02/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-16473
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8c89 summary report (pdf.gz) Map and 8c89 FULL report (pdf.gz)
EMICSS annotations (xml)

SARS-CoV-2 spike in complex with the 17T2 neutralizing antibody Fab fragment (local refinement of RBD and Fab)

EMD-16473

Single-particle
4.41 Å
EMD-16473
3D View Gallery
Deposition: 19/01/2023
Map released: 10/01/2024
Last modified: 21/02/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Severe acute respiratory syndrome coronavirus
Sample: SARS-CoV-2 Omicron Variant Spike Trimer in complex with three 17T2 Fabs
Fitted models: 8c89

Deposition Authors: Modrego A , Carlero D , Bueno-Carrasco MT , Santiago C , Carolis C , Arranz R , Blanco J , Magri G
A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity.
de Campos-Mata L , Trinite B , Modrego A , Tejedor Vaquero S , Pradenas E , Pons-Grifols A , Rodrigo Melero N, Carlero D , Marfil S, Santiago C , Raich-Regue D , Bueno-Carrasco MT , Tarres-Freixas F, Abanco F, Urrea V , Izquierdo-Useros N , Riveira-Munoz E , Ballana E, Perez M, Vergara-Alert J, Segales J , Carolis C , Arranz R , Blanco J , Magri G
(2024) Nat Commun , 15 , 1051 - 1051
PUBMED: 38316751
DOI: doi:10.1038/s41467-024-45171-9
ISSN: 2041-1723