EMD-19276
Cryo-EM of tetrameric collagenase-cleaved Xenopus ZP2-N2N3 (cleaved xZP2-N2N3) (C1)
EMD-19276
Single-particle4.6 Å
Deposition: 25/12/2023
Map released: 13/03/2024
Last modified: 27/03/2024
Sample Organism:
Xenopus laevis
Sample: Tetrameric collagenase-cleaved Xenopus ZP2-N2N3 (cleaved xZP2-N2N3)
Deposition Authors: Wiseman B , Nishio S , Jovine L
Sample: Tetrameric collagenase-cleaved Xenopus ZP2-N2N3 (cleaved xZP2-N2N3)
Deposition Authors: Wiseman B , Nishio S , Jovine L
ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat.
Nishio S ,
Emori C ,
Wiseman B ,
Fahrenkamp D ,
Dioguardi E ,
Zamora-Caballero S ,
Bokhove M ,
Han L ,
Stsiapanava A ,
Algarra B ,
Lu Y ,
Kodani M ,
Bainbridge RE ,
Komondor KM ,
Carlson AE ,
Landreh M ,
de Sanctis D ,
Yasumasu S ,
Ikawa M ,
Jovine L
(2024) Cell , 187 , 1440 - 1459.e24
(2024) Cell , 187 , 1440 - 1459.e24
Secondary citations:
- Gerton GL & Hedrick JL. (1986) The vitelline envelope to fertilization envelope conversion in eggs of Xenopus laevis. 116, 1 - 7
- Tian J, Gong H, Thomsen GH & Lennarz WJ. (1997) Gamete interactions in Xenopus laevis: identification of sperm binding glycoproteins in the egg vitelline envelope. J Cell Biol, 136, 1099 - 1108
- Tian J, Gong H, Thomsen GH & Lennarz WJ. (1997) Xenopus laevis sperm-egg adhesion is regulated by modifications in the sperm receptor and the egg vitelline envelope. 187, 143 - 153
- Tian J, Gong H & Lennarz WJ. (1999) Xenopus laevis sperm receptor gp69/64 glycoprotein is a homolog of the mammalian sperm receptor ZP2. PNAS, 96, 829 - 834
- Lindsay LL & Hedrick JL. (2004) Proteolysis of Xenopus laevis egg envelope ZPA triggers envelope hardening. 324, 648 - 654
- Scarpeci SL, Sanchez ML & Cabada MO. (2008) Cellular origin of the Bufo arenarum sperm receptor gp75, a ZP2 family member: its proteolysis after fertilization. 100, 219 - 230
- & Hedrick JL. (2008) Anuran and pig egg zona pellucida glycoproteins in fertilization and early development. 52, 683 - 701